Interleukin-6 and Interleukin-10 concentrations as predictors of patient outcome following major traumatic injury (2017)
Thesis
Jones, M. Interleukin-6 and Interleukin-10 concentrations as predictors of patient outcome following major traumatic injury. (Dissertation). University of Salford

Trauma is one of the main causes of death worldwide, accounting for 4.8 million deaths per year. This death rate has led to trauma being classed as the top cause of death for males, aged between fifteen and twenty-nine. More recently, however, the... Read More about Interleukin-6 and Interleukin-10 concentrations as predictors of patient outcome following major traumatic injury.

Characterisation of a novel bioactive complex polysaccharide from a marine invertebrate with potent anticancer and antimalarial activities (2017)
Thesis
Khurshid, C. A. Characterisation of a novel bioactive complex polysaccharide from a marine invertebrate with potent anticancer and antimalarial activities. (Thesis). ELS

Considerable excitement has been generated by the discovery of active compounds from marine organisms. These compounds have a remarkable role in cancer treatment, with fewer side effects on general health. Sulphated glycosaminoglycan (GAGs) are prese... Read More about Characterisation of a novel bioactive complex polysaccharide from a marine invertebrate with potent anticancer and antimalarial activities.

The effect of environmental stress and selective glucocorticoid receptor modulators on chicken and human leukaemia cells (2017)
Thesis
Al-ibadi, I. The effect of environmental stress and selective glucocorticoid receptor modulators on chicken and human leukaemia cells. (Thesis). University of Salford

Glucocorticoids (GCs) play important functions in human physiology, and are commonly prescribed anti-inflammatory and immunosuppressive drugs. GCs are used in treatment of childhood acute lymphocytic leukemia (ALL), however resistance to therapy and... Read More about The effect of environmental stress and selective glucocorticoid receptor modulators on chicken and human leukaemia cells.

Assessment of the efficacy of BTI Larvicide, VectoBac 12AS® (BTI AM65-52) against “nuisance” flies at water treatment plants in North West England (2017)
Thesis
Wenjere, S. Assessment of the efficacy of BTI Larvicide, VectoBac 12AS® (BTI AM65-52) against “nuisance” flies at water treatment plants in North West England. (Dissertation). University of Salford

In treating wastewater using percolating filters, nature employs diverse biota, which includes nematoceran larvae, to sustain filter function. This study sought to generate evidence on the efficacy of a Bacillus thuringiensis var. israelensis-deriv... Read More about Assessment of the efficacy of BTI Larvicide, VectoBac 12AS® (BTI AM65-52) against “nuisance” flies at water treatment plants in North West England.

Novel therapies for cancer treatment : designing high affinity selective ligands against SIRT1 enzyme (2017)
Thesis
Al-Sudani, B. Novel therapies for cancer treatment : designing high affinity selective ligands against SIRT1 enzyme. (Thesis). University of Salford

The word ‘Sirtuin’ or Sir2 proteins are a class of proteins that possess either mono-ADP-ribosyltransferase, or deacylase activity, including deacetylase. SIRT1 is the most studied mammalian Sirtuins and predominantly localised in the nucleus and cyt... Read More about Novel therapies for cancer treatment : designing high affinity selective ligands against SIRT1 enzyme.