Targeting cancer stem cell propagation with palbociclib, a CDK4/6 inhibitor: Telomerase drives tumor cell heterogeneity
(2016)
Journal Article
Bonuccelli, G., Peires-Pages, M., Ozsvari, B., Martinez- Outschoorn, U., Sotgia, F., & Lisanti, M. (2017). Targeting cancer stem cell propagation with palbociclib, a CDK4/6 inhibitor: Telomerase drives tumor cell heterogeneity. Oncotarget, 8(6), 9868-9884. https://doi.org/10.18632/oncotarget.14196
In this report, we systematically examined the role of telomerase activity in
lung and ovarian cancer stem cell (CSC) propagation. For this purpose, we indirectly
gauged telomerase activity, by linking the hTERT-promoter to eGFP. Using lung
(A549)...
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