Outputs (12)

Development and Characterization of Polymeric-based Biomaterial from Agro-Food Waste: A Sustainable and Eco-friendly Approach Towards Plastic Pollution. (2024)
Journal Article
Hussain, R., Aziz, A., Amin, R., & Khurshid, A. (2024). Development and Characterization of Polymeric-based Biomaterial from Agro-Food Waste: A Sustainable and Eco-friendly Approach Towards Plastic Pollution. Current Pharmaceutical Biotechnology, 26(4), 550-563. https://doi.org/10.2174/0113892010304507240528064315

Commercial plastics are potentially hazardous and can be carcinogenic due to the incorporation of chemical additives along with other additional components utilized as brominated flame retardants and phthalate plasticizers during production that exce... Read More about Development and Characterization of Polymeric-based Biomaterial from Agro-Food Waste: A Sustainable and Eco-friendly Approach Towards Plastic Pollution..

Circular and linear : a tale of aptamer selection for the activation of SIRT1 to induce death in cancer cells (2020)
Journal Article
Al-Sudani, B., Ragazzon-Smith, A., Aziz, A., Alansari, R., Ferry, N., Krstic- Demonacos, M., & Ragazzon, P. (2020). Circular and linear : a tale of aptamer selection for the activation of SIRT1 to induce death in cancer cells. RSC Advances, 10(73), 45008-45018. https://doi.org/10.1039/D0RA07857C

It is a challenge to select the right target to treat conditions without affecting non-diseased cells. Cancer belongs to the top 10 causes of death in the world and it remains difficult to treat. Amongst cancer emerging targets, silent information re... Read More about Circular and linear : a tale of aptamer selection for the activation of SIRT1 to induce death in cancer cells.

Living with Coronavirus (COVID-19) : a brief report (2020)
Journal Article

The world will never be same after the current COVID-19 pandemic. We may have to live with the coronavirus for a long time. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has resulted in a major burden on the global health... Read More about Living with Coronavirus (COVID-19) : a brief report.

Development of polymeric nanocomposite (Xyloglucan-co-Methacrylic acid/Hydroxyapatite/SiO 2 ) scaffold for bone tissue engineering applications—In-vitro antibacterial, cytotoxicity and cell culture evaluation (2020)
Journal Article

Advancement and innovation in bone regeneration, specifically polymeric composite scaffolds, are of high significance for the treatment of bone defects. Xyloglucan (XG) is a polysaccharide biopolymer having a wide variety of regenerative tissue thera... Read More about Development of polymeric nanocomposite (Xyloglucan-co-Methacrylic acid/Hydroxyapatite/SiO 2 ) scaffold for bone tissue engineering applications—In-vitro antibacterial, cytotoxicity and cell culture evaluation.

Dibenzoyl-methane derivatives as potential and exciting new therapy for the treatment of childhood bone cancer (2016)
Journal Article

Abstract. Childhood bone cancer though rare, has very limited treatment choices, with poor survival rates and often involving amputation. We have developed a novel molecule, 2', 4'-dihydroxy-dithion-dibenzoyl-methane and tested it on hepatic, colon,... Read More about Dibenzoyl-methane derivatives as potential and exciting new therapy for the treatment of childhood bone cancer.

Proceedings of the 12th international postgraduate research conference in the built environment (2015)
Book

JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease (2014)
Journal Article

Genomic regions of acquired uniparental disomy (UPD) are common in malignancy and frequently harbor mutated oncogenes. Homozygosity for such gain-of-function mutations is thought to modulate tumor phenotype, but direct evidence has been elusive. Poly... Read More about JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease.

Somatic CALR Mutations in myeloproliferative neoplasms with nonmutated JAK2 (2013)
Journal Article

BACKGROUND:
Somatic mutations in the Janus kinase 2 gene (JAK2) occur in many myeloproliferative neoplasms, but the molecular pathogenesis of myeloproliferative neoplasms with nonmutated JAK2 is obscure, and the diagnosis of these neoplasms remains... Read More about Somatic CALR Mutations in myeloproliferative neoplasms with nonmutated JAK2.

MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages (2009)
Journal Article
Aziz, A., Soucie, E., Sarrazin, S., & Sieweke, M. (2009). MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages. Science, 326(5954), 867-871. https://doi.org/10.1126/science.1176056

In metazoan organisms, terminal differentiation is generally tightly linked to cell cycle exit, whereas the undifferentiated state of pluripotent stem cells is associated with unlimited self-renewal. Here, we report that combined deficiency for the t... Read More about MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages.

MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages (2009)
Journal Article
Aziz, A., Soucie, E., Sarrazin, S., & Sieweke, M. (2009). MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages. Science, 326(5954), 867-871. https://doi.org/10.1126/science.1176056

In metazoan organisms, terminal differentiation is generally tightly linked to cell cycle exit, whereas the undifferentiated state of pluripotent stem cells is associated with unlimited self-renewal. Here, we report that combined deficiency for the t... Read More about MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages.