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Outputs (8)

Harnessing the Power of MicroRNA Cargoes in Small Extracellular Vesicles Released from Fresh-Frozen Human Brain Sections (2024)
Journal Article

Small extracellular vesicles (sEVs) are crucial mediators of cell-cell communication, transporting diverse cargoes like proteins, lipids, and nucleic acids (microRNA, mRNA, DNA). The microRNA sEV cargo has potential utility as a powerful non-invasive... Read More about Harnessing the Power of MicroRNA Cargoes in Small Extracellular Vesicles Released from Fresh-Frozen Human Brain Sections.

Alterations in Autophagy Marker Distribution in Different Genetic Subtypes of Frontotemporal Lobar Degeneration (2023)
Thesis

Frontotemporal dementia (FTD) is the second most common type of early-onset dementia and is characterised by impairments in language and behavioural changes whilst memory is normally well preserved; it can be clinically subdivided into behavioural va... Read More about Alterations in Autophagy Marker Distribution in Different Genetic Subtypes of Frontotemporal Lobar Degeneration.

Exploring the influence of adipokines on neuronal function in Alzheimer’s disease (2021)
Thesis
Tomar, N. Exploring the influence of adipokines on neuronal function in Alzheimer’s disease. (Thesis). University of Salford

Alzheimer’s disease (AD) is one of the major causes of dementia. Alzheimer’s disease is an irreversible, slow neurodegenerative disease leading to memory and language impairment and amyloid-β plaques and intraneuronal neurofibrillary tangles are the... Read More about Exploring the influence of adipokines on neuronal function in Alzheimer’s disease.

Investigation into Toxoplasma gondii infection in relation to expression of neurodegenerative disease markers in natural mice populations (2020)
Thesis

Toxoplasma gondii is a highly prevalent opportunistic protozoan parasite that has a remarkable capacity to infect humans and a range of warm-blooded animals. This research had two broad aims. Firstly, to investigating whether detection of T. gondii i... Read More about Investigation into Toxoplasma gondii infection in relation to expression of neurodegenerative disease markers in natural mice populations.

Perceptions of play : using Play-Doh to enhance the student experience in bioscience higher education (2017)
Journal Article
Lace-Costigan, G. (2017). Perceptions of play : using Play-Doh to enhance the student experience in bioscience higher education. International Journal of Game-Based Learning, 7(3), 26-37. https://doi.org/10.4018/IJGBL.2017070103

Playful and kinaesthetic learning approaches are used in numerous early years (birth to 5 years old) learning environments, however studies in HE STEM disciplines are uncommon. This study aimed to explore the use of Play-Doh in an undergraduate anato... Read More about Perceptions of play : using Play-Doh to enhance the student experience in bioscience higher education.

Investigating alterations in autophagy in Alzheimer’s disease using human brain tissue and skin-derived fibroblasts
Thesis

Alzheimer’s disease (AD) is the main cause of dementia, affecting 500,000 people in the UK. Pathology of AD is characterised by the accumulation of abnormally phosphorylated tau protein within neurofibrillary tangles and plaques containing amyloid-β... Read More about Investigating alterations in autophagy in Alzheimer’s disease using human brain tissue and skin-derived fibroblasts.