Outputs (154)

Revealing the progression and pathologic features of intraperitoneal infection of Trichomonas vaginalis in mice via parasite α-actinin-based immunological detection (2024)
Journal Article
Xie, Y., Zhang, C., Tang, P., Hide, G., Lai, D., & Lun, Z.-R. (in press). Revealing the progression and pathologic features of intraperitoneal infection of Trichomonas vaginalis in mice via parasite α-actinin-based immunological detection. BMC Infectious Diseases, 24, Article 1173. https://doi.org/10.1186/s12879-024-10041-8

Background: Trichomoniasis caused by Trichomonas vaginalis is the most prevalent nonviral sexually transmitted disease in women and has frequently damaged public health. To better use the animal model and take a step forward fully elucidating this pa... Read More about Revealing the progression and pathologic features of intraperitoneal infection of Trichomonas vaginalis in mice via parasite α-actinin-based immunological detection.

Toxoplasma gondii (2024)
Other
Hide, G. (2024). Toxoplasma gondii. [Video presentation of Lecture]

Multiomics of parkinsonism cynomolgus monkeys highlights significance of metabolites in interaction between host and microbiota (2024)
Journal Article

The gut microbiota has been demonstrated to play a significant role in the pathogenesis of Parkinson’s disease (PD). However, conflicting findings regarding specific microbial species have been reported, possibly due to confounding factors within hum... Read More about Multiomics of parkinsonism cynomolgus monkeys highlights significance of metabolites in interaction between host and microbiota.

Apicomplexa micropore: history, function, and formation (2024)
Journal Article
Yang, J., Long, S., Hide, G., Lun, Z.-R., & Lai, D.-H. (2024). Apicomplexa micropore: history, function, and formation. Trends in Parasitology, 40(5), S1471-4922(24)00079-5. https://doi.org/10.1016/j.pt.2024.03.008

The micropore, a mysterious structure found in apicomplexan species, was recently shown to be essential for nutrient acquisition in Plasmodium falciparum and Toxoplasma gondii. However, the differences between the micropores of these two parasites qu... Read More about Apicomplexa micropore: history, function, and formation.

First outbreak of trypanosomiasis in farmed blood parrot cichlids (Vieja melanura♀ × Amphilophus citrinellus♂) from southern China (2024)
Journal Article
Zhou (周), J.-Y. (., Xu (徐), L. (., Bi (毕), Y.-X. (., Zhang (章), J. (., Hide, G., Lai (赖), D.-H. (., & Lun (伦), Z.-R. (. (2024). First outbreak of trypanosomiasis in farmed blood parrot cichlids (Vieja melanura♀ × Amphilophus citrinellus♂) from southern China. Aquaculture, 588, 740944. https://doi.org/10.1016/j.aquaculture.2024.740944

Outbreaks of fish trypanosomiasis are regularly reported in cultured groupers (Epinephelus spp.), largemouth bass (Micropterus salmoides), and many other species of Cyprinidae, but only rarely reported in ornamental fish. This study reports a trypano... Read More about First outbreak of trypanosomiasis in farmed blood parrot cichlids (Vieja melanura♀ × Amphilophus citrinellus♂) from southern China.

The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival (2024)
Journal Article

The apicoplast is a four-membrane plastid found in the apicomplexans, which harbors biosynthesis and organelle housekeeping activities in the matrix. However, the mechanism driving the flux of metabolites, in and out, remains unknown. Here, we used T... Read More about The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival.

The transplant rejection response involves neutrophil and macrophage adhesion-mediated trogocytosis and is regulated by NFATc3 (2024)
Journal Article

The anti-foreign tissue (transplant rejection) response, mediated by the immune system, has been the biggest obstacle to successful organ transplantation. There are still many enigmas regarding this process and some aspects of the underlying mechanis... Read More about The transplant rejection response involves neutrophil and macrophage adhesion-mediated trogocytosis and is regulated by NFATc3.

Prevalence of Eimeria Species, Detected by ITS1-PCR Immobilized on FTA Cards, in Future Laying Hens and Breeding Hens in Six Provinces in Northeastern Algeria (2024)
Journal Article
Ayadi, O., Djemai, S., & Hide, G. (2024). Prevalence of Eimeria Species, Detected by ITS1-PCR Immobilized on FTA Cards, in Future Laying Hens and Breeding Hens in Six Provinces in Northeastern Algeria. Acta parasitologica / Witold Stefański Institute of Parasitology, https://doi.org/10.1007/s11686-023-00773-z

Purpose
Avian coccidiosis is an important and widely distributed disease that affects global agricultural economies through losses. In Algeria, there is limited epidemiological and ecological knowledge about this disease and this hinders implementat... Read More about Prevalence of Eimeria Species, Detected by ITS1-PCR Immobilized on FTA Cards, in Future Laying Hens and Breeding Hens in Six Provinces in Northeastern Algeria.

Macrophage-mediated trogocytosis contributes to destroying human schistosomes in a non-susceptible rodent host, Microtus fortis (2023)
Journal Article

Schistosoma parasites, causing schistosomiasis, exhibit typical host specificity in host preference. Many mammals, including humans, are susceptible to infection, while the widely distributed rodent, Microtus fortis, exhibits natural anti-schistosome... Read More about Macrophage-mediated trogocytosis contributes to destroying human schistosomes in a non-susceptible rodent host, Microtus fortis.

Functional screening reveals Toxoplasma prenylated proteins required for endocytic trafficking and rhoptry protein sorting (2023)
Journal Article

In the apicomplexans, endocytosed cargos (e.g., hemoglobin) are trafficked to a specialized organelle for digestion. This follows a unique endocytotic process at the micropore/cytostome in these parasites. However, the mechanism underlying endocytic... Read More about Functional screening reveals Toxoplasma prenylated proteins required for endocytic trafficking and rhoptry protein sorting.