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Outputs (348)

Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer (2012)
Journal Article
Tucci, P., Agostini, M., Grespi, F., Merkert, E., Terrinoni, A., Vousden, K., …Sayan, B. (2012). Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer. Proceedings of the National Academy of Sciences, 109(38), https://doi.org/10.1073/pnas.1110977109

p63 inhibits metastasis. Here, we show that p63 (both TAp63 and ΔNp63 isoforms) regulates expression of miR-205 in prostate cancer (PCa) cells, and miR-205 is essential for the inhibitory effects of p63 on markers of epithelial–mesenchymal transition... Read More about Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer.

Investment appraisal tools and sustainability evaluation in social housing (2012)
Presentation / Conference
Higham, A., & Fortune, C. (2012, September). Investment appraisal tools and sustainability evaluation in social housing. Presented at Association of Researchers in Construction Management (ARCOM) 28th Annual Conference, Edinburgh

Conventional decision making in all aspects of the asset management sector has largely been based around the key concepts of risk reduction and maximization of returns. Yet the RICS (2009) has called for surveying professionals to significantly modif... Read More about Investment appraisal tools and sustainability evaluation in social housing.

Attaining zero defects within Building Schools for the Future : A realistic target or a Sisyphean task? (2012)
Presentation / Conference
Higham, A., Boothman, J., & Horsfall, B. (2012, September). Attaining zero defects within Building Schools for the Future : A realistic target or a Sisyphean task?. Presented at 27th Annual Association of Researchers in Construction Management (ARCOM) Conference, Edinburgh, UK

Until its demise in July 2010 The Building Schools for the Future (BSF) programme represented the biggest single UK government investment in school buildings for more than 50 years. One of the key goals of the investment programme was the desire to e... Read More about Attaining zero defects within Building Schools for the Future : A realistic target or a Sisyphean task?.

Engaging life in two Irish nursing home units for people with dementia : quantitative comparisons before and after implementing household environments (2012)
Journal Article
Morgan_Brown, M., Ormerod, M., & Newton, R. (2012). Engaging life in two Irish nursing home units for people with dementia : quantitative comparisons before and after implementing household environments. Aging & mental health, 17(1), 57-65. https://doi.org/10.1080/13607863.2012.717250

This study compares the Social Engagement and Interactive Occupation of residents with dementia in two Irish nursing homes, before and after conversion to a household model environment. The changes were an open plan design and a functioning unit kitc... Read More about Engaging life in two Irish nursing home units for people with dementia : quantitative comparisons before and after implementing household environments.

Impacts of flooding on SMEs and their relevance to chartered surveyors : final report of the developing flood expert knowledge in chartered surveyors - DEFENCES project (2012)
Report
Wedawatta, H., Ingirige, B., & Proverbs, D. (2012). Impacts of flooding on SMEs and their relevance to chartered surveyors : final report of the developing flood expert knowledge in chartered surveyors - DEFENCES project

The UK has endured a number of major flood events in recent years, and the UK Environment Agency (2009a) identified that about 5.2million properties in England, amounting to one in six, are at risk of flooding. The impacts of flooding include d... Read More about Impacts of flooding on SMEs and their relevance to chartered surveyors : final report of the developing flood expert knowledge in chartered surveyors - DEFENCES project.

Time domain analysis of Helmholtz soliton propagation using the TLM method (2012)
Journal Article
Chamorro-Posada, P., & McDonald, G. (2012). Time domain analysis of Helmholtz soliton propagation using the TLM method. Journal of Nonlinear Optical Physics and Materials, 21(03), https://doi.org/10.1142/S0218863512500312

The transmission line matrix method is used to study Helmholtz solitons as solutions of the two-dimensional time-domain Maxwell equations in nonlinear media. This approach permits to address, in particular, the propagation and intrinsic stability pr... Read More about Time domain analysis of Helmholtz soliton propagation using the TLM method.

Modelling stress-strain and volume change behaviour of unsaturated soils using an evolutionary based data mining technique, an incremental approach (2012)
Journal Article
Javadi, A., Ahangar-Asr, A., Johari, A., Faramarzi, A., & Toll, D. (2012). Modelling stress-strain and volume change behaviour of unsaturated soils using an evolutionary based data mining technique, an incremental approach. Engineering Applications of Artificial Intelligence, 25(5), 926-933. https://doi.org/10.1016/j.engappai.2012.03.006

Modelling of unsaturated soils has been the subject of many research works in the past few decades. A number of constitutive models have been developed to describe the complex behaviour of unsaturated soils. However, many have proven to be unable to... Read More about Modelling stress-strain and volume change behaviour of unsaturated soils using an evolutionary based data mining technique, an incremental approach.

Determination of the most probable slip surface in 3D slopes considering the effect of earthquake force direction (2012)
Journal Article
Ahangar-Asr, A., Toufigh, M., & Salajegheh, A. (2012). Determination of the most probable slip surface in 3D slopes considering the effect of earthquake force direction. Computers and Geosciences, 45, 119-130. https://doi.org/10.1016/j.cageo.2011.10.024

Considering the effect of earthquake forces on stability of slopes has always been of crucial importance in seismic analysis of geotechnical structures like dams, roads and embankments and there has been much concern about stability of cuts, fills an... Read More about Determination of the most probable slip surface in 3D slopes considering the effect of earthquake force direction.