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Outputs (524)

A 2-step synthesis of Combretastatin A-4 and derivatives as potent tubulin assembly inhibitors (2020)
Journal Article
Barnes, N., Parker, A., Mal Ullah, A., Ragazzon, P., & Hadfield, J. (2020). A 2-step synthesis of Combretastatin A-4 and derivatives as potent tubulin assembly inhibitors. Bioorganic and Medicinal Chemistry, 28(19), 115684. https://doi.org/10.1016/j.bmc.2020.115684

A series of combretastatin derivatives were designed and synthesised by a two-step stereoselective synthesis by use of Wittig olefination followed by Suzuki cross-coupling. Interestingly, all new compounds (2a-2i) showed potent cell-based antiprolife... Read More about A 2-step synthesis of Combretastatin A-4 and derivatives as potent tubulin assembly inhibitors.

Unsteady nonlinear magnetohydrodynamic micropolar transport phenomena with hall and ion-slip current effects : numerical study (2020)
Journal Article
Beg, O., Beg, T., Ferdows, M., Vasu, B., Kadir, A., Leonard, H., & Kuharat, S. (2021). Unsteady nonlinear magnetohydrodynamic micropolar transport phenomena with hall and ion-slip current effects : numerical study. International Journal of Applied Electromagnetics and Mechanics, 65(2), 371-403. https://doi.org/10.3233/JAE-201508

Unsteady viscous two-dimensional magnetohydrodynamic micropolar flow, heat and mass transfer from an infinite vertical surface with Hall and Ion-slip currents is investigated theoretically and numerically. The simulation presented is motivated by el... Read More about Unsteady nonlinear magnetohydrodynamic micropolar transport phenomena with hall and ion-slip current effects : numerical study.

An integration of train timetabling, platforming and routing-based cooperative adjustment methodology for dealing with train delay (2020)
Journal Article
Zhang, Y., Chen, Z., An, M., & Umar, A. (2020). An integration of train timetabling, platforming and routing-based cooperative adjustment methodology for dealing with train delay. International Journal of Software Engineering and Knowledge Engineering, 30(07), 901-919. https://doi.org/10.1142/S0218194020400112

Train delay is a serious issue that can spread rapidly in the railway network leading to further delay of other trains and detention of passengers in stations. However, the current practice in the event of the trail delay usually depends on train dis... Read More about An integration of train timetabling, platforming and routing-based cooperative adjustment methodology for dealing with train delay.

Consideration of possible futures for peri-urban sites based on restabilising ecosystem processes : rewilding nature and people (2020)
Thesis
Bradley, T. Consideration of possible futures for peri-urban sites based on restabilising ecosystem processes : rewilding nature and people. (Dissertation). University of Salford

Inadequate funding, the shifting baseline syndrome phenomena, and the prescribe and protect approach to conservation collectively hinders ecosystem function. Rewilding offers an alternative solution without the same limitations. While it is documente... Read More about Consideration of possible futures for peri-urban sites based on restabilising ecosystem processes : rewilding nature and people.

Applying the core microbiome to understand host–microbe systems (2020)
Journal Article
Risely, A. (2020). Applying the core microbiome to understand host–microbe systems. Journal of Animal Ecology, 89(7), 1549-1558. https://doi.org/10.1111/1365-2656.13229

The host-associated core microbiome was originally coined to refer to common groups of microbes or genes that were likely to be particularly important for host biological function. However, the term has evolved to encompass variable definitions acros... Read More about Applying the core microbiome to understand host–microbe systems.

Cholesterol and mevalonate : two metabolites involved in breast cancer progression and drug resistance through the ERRα pathway (2020)
Journal Article
Brindisi, M., Fiorillo, M., Frattaruolo, L., Sotgia, F., Lisanti, M., & Cappello, A. (2020). Cholesterol and mevalonate : two metabolites involved in breast cancer progression and drug resistance through the ERRα pathway. Cells, 9(8), e1819. https://doi.org/10.3390/cells9081819

Breast cancer is the second greatest cause of cancer-related death in women. Resistance to endocrine treatments or chemotherapy is a limiting drawback. In this context, this work aims to evaluate the effects of cholesterol and mevalonate during tumor... Read More about Cholesterol and mevalonate : two metabolites involved in breast cancer progression and drug resistance through the ERRα pathway.

Critical success factors for implementing ISO 9001 in UK construction projects (2020)
Thesis
Aburas, M. Critical success factors for implementing ISO 9001 in UK construction projects. (Thesis). University of Salford

Numerous challenges face construction companies in today's competitive market, including the complex and contractually varied relationships of those involved; the nature of construction projects producing unique, non-repetitive outcomes; the lack of... Read More about Critical success factors for implementing ISO 9001 in UK construction projects.

Commentary : the effects of inflammation, aging, and oxidative stress on the pathogenesis of Type II Diabetes (2020)
Journal Article
on the pathogenesis of Type II Diabetes. https://doi.org/10.36502/2020/hcr.6169

Type II Diabetes Mellitus (T2DM) is a high-risk metabolic condition associated with high mortality due to hyperglycemia. Many studies have focused on how inflammation, aging, or oxidative stress influences the pathogenesis of T2DM. The functional ano... Read More about Commentary : the effects of inflammation, aging, and oxidative stress on the pathogenesis of Type II Diabetes.

Collaborative multidisciplinary learning : quantity surveying students’ perspectives (2020)
Journal Article
Ekundayo, D., Shelbourn, M., & Babatunde, S. (2021). Collaborative multidisciplinary learning : quantity surveying students’ perspectives. Industry and Higher Education, 35(3), 211-222. https://doi.org/10.1177/0950422220944127

The construction industry is highly fragmented and is known for its adversarial culture, culminating in poor quality projects not completed on time or within budget. The aim of this study is thus to guide the design of QS programme curricula in ord... Read More about Collaborative multidisciplinary learning : quantity surveying students’ perspectives.