Role of epigenetic modifications in inhibitory immune checkpoints in cancer development and progression
(2020)
Journal Article
Saleh, R., Toor, S., Sasidharan Nair, V., & Elkord, E. (2020). Role of epigenetic modifications in inhibitory immune checkpoints in cancer development and progression. Frontiers in Immunology, 11, 1469. https://doi.org/10.3389/fimmu.2020.01469
A balance between co-inhibitory and co-stimulatory signals in the tumor microenvironment (TME) is critical to suppress tumor development and progression, primarily via maintaining effective immunosurveillance. Aberrant expression of immune checkpoint... Read More about Role of epigenetic modifications in inhibitory immune checkpoints in cancer development and progression.