Outputs (5)

Selected derivatives of erythromycin B- in silico and anti-malarial studies (2021)
Journal Article
Bhadra, P., Magwaza, R., Nirmalan, N., Freeman, S., Barber, J., & Arsic, B. (2021). Selected derivatives of erythromycin B- in silico and anti-malarial studies. Materials, 14(22), e6980. https://doi.org/10.3390/ma14226980

Erythromycin A is an established anti-bacterial agent against Gram-positive bacteria, but it is unstable to acid. This led to an evaluation of erythromycin B and its derivatives because these have improved acid stability. These compounds were investi... Read More about Selected derivatives of erythromycin B- in silico and anti-malarial studies.

Co-creation and empowerment: pathways to better student engagement (2021)
Other
Namvar, S., Greensmith, D., & Nirmalan, N. (2021). Co-creation and empowerment: pathways to better student engagement. THE Campus

Progression and employability are at the forefront of current conversations in higher education, with much effort invested in developing complex interventions to improve graduate outcomes. Pedagogy research indicates that factors such as a sense of b... Read More about Co-creation and empowerment: pathways to better student engagement.

Improved biopharmaceutical attributes of lumefantrine using choline mimicking drug delivery system : preclinical investigation on NK-65 P.berghei murine model (2021)
Journal Article
Kaur, R., Gorki, V., Katare, O., Dhingra, N., Chauhan, M., Kaur, R., …Singh, B. (2021). Improved biopharmaceutical attributes of lumefantrine using choline mimicking drug delivery system : preclinical investigation on NK-65 P.berghei murine model. Expert Opinion on Drug Delivery, 18(10), 1533-1552. https://doi.org/10.1080/17425247.2021.1946512

Background Lumefantrine (LMF) is first-line antimalarial drug, possesses activity against almost all human malarial parasites, but the in vivo activity of this molecule gets thwarted due to its low and inconsistent oral bioavailability (i.e. 4–12%)... Read More about Improved biopharmaceutical attributes of lumefantrine using choline mimicking drug delivery system : preclinical investigation on NK-65 P.berghei murine model.

Major traumatic injury : serum cytokine biomarkers as predictors of poor clinical outcome (2021)
Thesis
Ramaswamy, D. Major traumatic injury : serum cytokine biomarkers as predictors of poor clinical outcome. (Dissertation). University of Salford

Trauma is a leading cause of mortality and morbidity worldwide, accounting for about 5.8 million deaths annually. England alone sees approximately 25,000 cases of major trauma each year and over a fourth of these result in loss of life. Death due t... Read More about Major traumatic injury : serum cytokine biomarkers as predictors of poor clinical outcome.

Investigating Interleukin – 8 and TGF Beta as early biomarkers predicting poor clinical outcome in major trauma (2021)
Thesis
Abbood, L. Investigating Interleukin – 8 and TGF Beta as early biomarkers predicting poor clinical outcome in major trauma. (Dissertation). University of Salford

Trauma is a leading cause of death and disability. Globally, traumatic injury is the main cause of death under the age of 45. Recent studies from the UK report a demographic change in major trauma. The most common mechanism of traumatic injury is fal... Read More about Investigating Interleukin – 8 and TGF Beta as early biomarkers predicting poor clinical outcome in major trauma.