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Electrochemical detection of asparaginase antibodies using bifunctionalized carbon interfaces (2023)
Journal Article
Marshall, D., & Lehr, J. (in press). Electrochemical detection of asparaginase antibodies using bifunctionalized carbon interfaces. Electroanalysis, https://doi.org/10.1002/elan.202200456

The early detection of anti-asparaginase biomarker can facilitate timely modification of asparaginase chemotherapy, thereby avoiding serious complications. Herein we describe the preparation of a novel electrochemical biosensing interface for rapid d... Read More about Electrochemical detection of asparaginase antibodies using bifunctionalized carbon interfaces.

Label‐free Selective Detection of Protein Markers in the Picomolar Range via a Convenient Voltammetric Sensing Strategy (2021)
Journal Article
Chen, C., Chen, C., & Lehr, J. (2021). Label‐free Selective Detection of Protein Markers in the Picomolar Range via a Convenient Voltammetric Sensing Strategy. Electroanalysis, 33(3), 563-567. https://doi.org/10.1002/elan.202060308

AbstractA convenient strategy for the preparation of label‐free selective protein biomarker sensors is presented. After formation of a ferrocene terminated monolayer on a gold electrode using thiol chemistry, grafting of an antifouling phenylalanine... Read More about Label‐free Selective Detection of Protein Markers in the Picomolar Range via a Convenient Voltammetric Sensing Strategy.

Mapping the ionic fingerprints of molecular monolayers (2017)
Journal Article
Lehr, J., Weeks, J., Santos, A., Feliciano, G., Nicholson, M., Davis, J., & Bueno, P. (2017). Mapping the ionic fingerprints of molecular monolayers. Physical Chemistry Chemical Physics, 19(23), 15098-15109. https://doi.org/10.1039/c7cp01500c

We have previously proposed, and experimentally resolved, an ionic charge relaxation model for redox inactive self-assembled monolayers (SAMs) on metallic electrodes in contact with a liquid electrolyte. Here we analyse, by capacitance spectroscopy,... Read More about Mapping the ionic fingerprints of molecular monolayers.

Ratiometric oxygen sensing using lanthanide luminescent emitting interfaces (2015)
Journal Article
Lehr, J., Tropiano, M., Beer, P., Faulkner, S., & Davis, J. (2015). Ratiometric oxygen sensing using lanthanide luminescent emitting interfaces. Chemical Communications, 51(88), 15944-15947. https://doi.org/10.1039/c5cc05738h

Herein we describe the first example of a ratiometric lanthanide luminescent oxygen sensing interface. Immobilisation of terbium and europium cyclen complexes on glass substrates was achieved by a novel aryl nitrene photografting approach. The result... Read More about Ratiometric oxygen sensing using lanthanide luminescent emitting interfaces.

Reversible redox modulation of a lanthanide emissive molecular film (2015)
Journal Article
Lehr, J., Tropiano, M., Beer, P., Faulkner, S., & Davis, J. (2015). Reversible redox modulation of a lanthanide emissive molecular film. Chemical Communications, 51(30), 6515-6517. https://doi.org/10.1039/c5cc01097g

Herein we demonstrate redox switchable emission from a sensitised, europium–ferrocene containing, molecular film assembled by a novel nitrene-based strategy. Electrochemical modulation of europium emission upon switching the ferrocene moiety's redox... Read More about Reversible redox modulation of a lanthanide emissive molecular film.

Graphene oxide interfaces in serum based autoantibody quantification (2014)
Journal Article
Xu, Q., Cheng, H., Lehr, J., Patil, A., & Davis, J. (2015). Graphene oxide interfaces in serum based autoantibody quantification. Analytical Chemistry, 87(1), 346-350. https://doi.org/10.1021/ac503890e

A reliable quantification of protein markers will undoubtedly underpin profound developments in disease surveillance, diagnostics, and improved therapy. Although there potentially exist numerous means of achieving this, electrochemical impedimetric t... Read More about Graphene oxide interfaces in serum based autoantibody quantification.

Formation of thick aminophenyl films from aminobenzenediazonium ion in the absence of a reduction source (2014)
Journal Article
Simons, B., Lehr, J., Garrett, D., & Downard, A. (2014). Formation of thick aminophenyl films from aminobenzenediazonium ion in the absence of a reduction source. Langmuir, 30(17), 4989-4996. https://doi.org/10.1021/la501217n

Aminophenyl films, electrografted to conducting substrates from a solution of the corresponding diazonium ion, are a useful platform for building up functional surfaces. In our hands, reproducible preparation of aminophenyl films via electrografting... Read More about Formation of thick aminophenyl films from aminobenzenediazonium ion in the absence of a reduction source.

Exploiting lanthanide luminescence in supramolecular assemblies (2014)
Journal Article
Lehr, J., Beer, P., Faulkner, S., & Davis, J. (2014). Exploiting lanthanide luminescence in supramolecular assemblies. Chemical Communications, 50(43), 5678-5687. https://doi.org/10.1039/c4cc01138d

Lanthanide ions, due to their unique photo-physical characteristics, have attracted considerable attention in recent years. Their long lifetimes, sharp, well-defined emission bands, and designable environmental sensitivity make them ideal for integra... Read More about Exploiting lanthanide luminescence in supramolecular assemblies.

Label-free capacitive diagnostics : exploiting local redox probe state occupancy (2014)
Journal Article
Lehr, J., Fernandes, F., Bueno, P., & Davis, J. (2014). Label-free capacitive diagnostics : exploiting local redox probe state occupancy. Analytical Chemistry, 86(5), 2559-2564. https://doi.org/10.1021/ac403727h

An electrode surface confined redox group contributes to a substantial potential-dependent interfacial charging that can be sensitively probed and frequency-resolved by impedance-derived capacitance spectroscopy. In utilizing the sensitivity of this... Read More about Label-free capacitive diagnostics : exploiting local redox probe state occupancy.

Anion sensing by solution- and surface-assembled osmium(II) bipyridyl rotaxanes (2013)
Journal Article
Lehr, J., Lang, T., Blackburn, O., Barendt, T., Faulkner, S., Davis, J., & Beer, P. (2013). Anion sensing by solution- and surface-assembled osmium(II) bipyridyl rotaxanes. Chemistry - A European Journal, 19(47), 15898-15906. https://doi.org/10.1002/chem.201302886

We report the preparation of [2]rotaxanes containing an electrochemically and optically active osmium(II) bipyridyl macrocyclic component mechanically bonded with cationic pyridinium axles. Such interlocked host systems are demonstrated to recognise... Read More about Anion sensing by solution- and surface-assembled osmium(II) bipyridyl rotaxanes.