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Outputs (15273)

pH plays a role in the mode of action of trimethoprim on Escherichia coli (2018)
Journal Article
AlRabiah, H., Allwood, J., Correa, E., Xu, Y., & Goodacre, R. (2018). pH plays a role in the mode of action of trimethoprim on Escherichia coli. PLoS ONE, 13(7), e0200272. https://doi.org/10.1371/journal.pone.0200272

Metabolomics-based approaches were applied to understand interactions of trimethoprim with Escherichia coli K-12 at sub-minimum inhibitory concentrations (MIC≈0.2, 0.03 and 0.003 mg L-1). Trimethoprim inhibits dihydrofolate reductase and thereby is a... Read More about pH plays a role in the mode of action of trimethoprim on Escherichia coli.

Active bacterioplankton community response to dissolved ‘free’ deoxyribonucleic acid (dDNA) in surface coastal marine waters (2018)
Journal Article
Taylor, J., Bird, K., Widdicome, C., & Cunliffe, M. (2018). Active bacterioplankton community response to dissolved ‘free’ deoxyribonucleic acid (dDNA) in surface coastal marine waters. FEMS Microbiology Ecology, 94(10), https://doi.org/10.1093/femsec/fiy132

Seawater contains dissolved ‘free’ DNA (dDNA) that is part of a larger <0.2 μm pool of DNA (D-DNA) including viruses and uncharacterised bound DNA. Previous studies have shown that bacterioplankton readily degrade dDNA and culture-based approaches... Read More about Active bacterioplankton community response to dissolved ‘free’ deoxyribonucleic acid (dDNA) in surface coastal marine waters.

Radiocaesium transfer and radiation exposure of frogs in Fukushima Prefecture (2018)
Journal Article
Tagami, K., Uchida, S., Wood, M., & Beresford, N. (2018). Radiocaesium transfer and radiation exposure of frogs in Fukushima Prefecture. Scientific reports, 8(1), 10662. https://doi.org/10.1038/s41598-018-28866-0

The International Commission on Radiological Protection has proposed an environmental assessment framework. This includes ionising radiation exposure assessment for different frog life-stages, but radiocaesium transfer parameters are unavailable. We... Read More about Radiocaesium transfer and radiation exposure of frogs in Fukushima Prefecture.

Titi monkey biogeography : parallel Pleistocene spread by Plecturocebus and Cheracebus into a post-Pebas Western Amazon (2018)
Journal Article
Byrne, H., Lynch Alfaro, J., Sampaio, I., Farias, I., Schneider, H., Hrbek, T., & Boubli, J. (2018). Titi monkey biogeography : parallel Pleistocene spread by Plecturocebus and Cheracebus into a post-Pebas Western Amazon. Zoologica Scripta, 47(5), 499-517. https://doi.org/10.1111/zsc.12300

Titi monkeys, subfamily Callicebinae, are a diverse, species‐rich group of Neotropical primates with an extensive range across South America. Their distribution in space and time makes them an interesting primate model for addressing questions of Neo... Read More about Titi monkey biogeography : parallel Pleistocene spread by Plecturocebus and Cheracebus into a post-Pebas Western Amazon.

Design factors for a successful shared space street (SSS) design (2018)
Journal Article
Jayakody, R., Keraminiyage, K., Alston, M., & Dias, N. (2018). Design factors for a successful shared space street (SSS) design. International Journal of Strategic Property Management, 22(4), 278-289. https://doi.org/10.3846/ijspm.2018.3685

The concept of Shared Space Street (SSS) has the potential to bring many benefits to a city. Those include promotion of social interaction, the connectivity within the city for both vehicles and pedestrians, active engagement of the people with the s... Read More about Design factors for a successful shared space street (SSS) design.

Critical success factors of a bottom up urban design process to deliver sustainable urban designs (2018)
Journal Article
Dias, N., Keraminiyage, K., Amaratunga, R., & Curwell, S. (2018). Critical success factors of a bottom up urban design process to deliver sustainable urban designs. International Journal of Strategic Property Management, 22(4), 265-277. https://doi.org/10.3846/ijspm.2018.3683

A sustainable urban environment caters for peoples’ need. When the needs of the people are addressed, it increases the property values and attracts investors. The current urban design process is top-down, i.e., Designers and planners play the key rol... Read More about Critical success factors of a bottom up urban design process to deliver sustainable urban designs.

Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays (2018)
Journal Article
Berry, S., Hameed, H., Thomason, A., Maciej-Hulme, M., Saif Abou-Akkada, S., Horrocks, P., & Price, H. (2018). Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays. PLoS Neglected Tropical Diseases, 12(7), e0006639. https://doi.org/10.1371/journal.pntd.0006639

The protozoan parasite Leishmania causes leishmaniasis; a spectrum of diseases of which there are an estimated 1 million new cases each year. Current treatments are toxic, expensive, difficult to administer, and resistance to them is emerging. New th... Read More about Development of NanoLuc-PEST expressing Leishmania mexicana as a new drug discovery tool for axenic- and intramacrophage-based assays.

Optimal spaces for those living with dementia : principles and evidence (2018)
Journal Article
Barrett, P., Sharma, M., & Zeisel, J. (2018). Optimal spaces for those living with dementia : principles and evidence. Building Research and Information, 47(6), 734-746. https://doi.org/10.1080/09613218.2018.1489473

This paper represents a synthesis of diverse and disparate evidence in the research literature that provide insights into the impacts of aspects of the built environment on the wellbeing of those living with dementia. The individually focused findin... Read More about Optimal spaces for those living with dementia : principles and evidence.