The effect of resistance training on functional capacity in middle-aged to elderly individuals with peripheral artery disease: a meta-analysis

Pearson, S; Sindall, PA; Caldow, EJ; Taberner, P

Abstract

Peripheral artery disease (PAD) is an ischemic disease of the lower limbs, caused by atherosclerotic plaques, leading to impairments in functional capacity and reduced quality of life. This meta-analysis aimed to assess the effect of 12-week and 24-week resistance training (RT) interventions on 6-minute walking distance (6WMD) and initial claudication distance (ICD) measured during a 6-minute walk test (6MWT). A meta-analysis was conducted in accordance with PRISMA guidelines, with an electronic search conducted using the online database of PUBMED. Methodological quality of all included studies was completed using a modified version of the Newcastle Ottawa Scale (NOS). The effect sizes (ES) of 6MWD and ICD were calculated, with the 12-week and 24-week interventions analysed separately. An initial literature search yielded 1973 results that were consequently reduced to 7 studies to be included in the final meta-analysis. The pooled effect size for 6MWD for 12-week and 24-week interventions was ES = 0.189 [95% CI= -0.074 to 0.451] P = 0.159 and ES = 0.298 [95% CI = -0.036 to 0.631] P = 0.080 respectively. For ICD, ES = 0.498 [95% CI = 0.000 to 0.995] P = 0.050 and ES = 1.106 [95% CI = 0.120 to 0.428] P = 0.001 respectively. Short-term RT interventions have a positive effect on functional capacity in middle-aged to elderly individuals with PAD. There was a greater effect on ICD compared to 6MWD, with 24-week interventions showing larger effects for both measures. Improvements in functional capacity in such populations confers significant potential for positive health outcomes.

Citation

Pearson, S., Sindall, P., Caldow, E., & Taberner, P. (2022). The effect of resistance training on functional capacity in middle-aged to elderly individuals with peripheral artery disease: a meta-analysis. International angiology : a journal of the International Union of Angiology, https://doi.org/10.23736/S0392-9590.22.04922-7

• Journal Article Type: Article
• Publication Date: Oct 4, 2022
• Deposit Date: Dec 8, 2022
• Journal: International angiology : a journal of the International Union of Angiology
• Print ISSN: 0392-9590
• Electronic ISSN: 1827-1839
• Publisher: Edizioni Minerva Medica
• DOI: https://doi.org/10.23736/S0392-9590.22.04922-7
• Publisher URL: https://doi.org/10.23736/S0392-9590.22.04922-7