Using the common cold virus as a naturally occurring vaccine to prevent COVID-19 : lessons from Edward Jenner

Sotgia, F; Lisanti, MP

Abstract

Three recent papers published in Nature, Science and Cell, all present clear evidence that there is cross-reactive T-cell immunity between human coronaviruses (229E, NL63, OC43, and HKU1), linked with the common cold, and SARS-CoV-2, the causative agent of COVID-19. Can we use this information to design and build a new vaccine based on the less pathogenic, common cold coronaviruses, for the prevention of COVID-19? If we look at the history of medicine and vaccine development, from the point of view of Edward Jenner, the answer just might be yes.

Citation

Sotgia, F., & Lisanti, M. (2020). Using the common cold virus as a naturally occurring vaccine to prevent COVID-19 : lessons from Edward Jenner. Aging, 12(19), 18797-18803. https://doi.org/10.18632/aging.104166

• Journal Article Type: Article
• Acceptance Date: Sep 30, 2020
• Publication Date: Oct 13, 2020
• Deposit Date: Nov 16, 2020
• Publicly Available Date: Nov 16, 2020
• Journal: Aging
• Publisher: Impact Journals
• Volume: 12
• Issue: 19
• Pages: 18797-18803
• DOI: https://doi.org/10.18632/aging.104166
• Publisher URL: https://doi.org/10.18632/aging.104166
• Related Public URLs: http://www.impactaging.com/
• Additional Information: Additional Information : ** From PubMed via Jisc Publications Router **Journal IDs: eissn 1945-4589 **Article IDs: pubmed: 33049711; pii: 104166 **History: accepted 30-09-2020; submitted 18-09-2020