Antimicrobial activity against hospital-related pathogens of
dual layer CuO/TiO2 coatings prepared by CVD

Foster, HA; Sheel, DW; Evans, P; Sheel, P; Varghese, S; Elfakhri, SO; Hodgkinson, JL; Yates, HM

Abstract

Photocatalytically active films of TiO2/CuO grown by atmospheric pressure thermal (APT)CVD are investigated for activity against multiple antibiotic-resistant pathogens namely, Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae, vancomycin-resistant enterococci (VRE), and a recent isolate of methicillin-resistant Staphylococcus aureus (MRSA), that have been shown to persist in the hospital environment. The bacteria are killed by UVA irradiation of the photocatalyst with a>5 log kill within 4–6 h except for the MRSA where a 2–3 log kill is obtained after 6 h increasing to >5 log after 24 h. There is antimicrobial activity in the dark which is enhanced by irradiation with fluorescent light. There is also activity at 5 8C under UVA, but activity is lower when fluorescent light is used for illumination.

Citation

dual layer CuO/TiO2 coatings prepared by CVD. Chemical Vapor Deposition, 18(4-6), 140-146. https://doi.org/10.1002/cvde.201106978

• Journal Article Type: Article
• Publication Date: Jun 1, 2012
• Deposit Date: Jun 8, 2015
• Journal: Chemical Vapor Deposition
• Print ISSN: 0948-1907
• Electronic ISSN: 1521-3862
• Publisher: Wiley-VCH Verlag
• Peer Reviewed: Peer Reviewed
• Volume: 18
• Issue: 4-6
• Pages: 140-146
• DOI: https://doi.org/10.1002/cvde.201106978
• Publisher URL: http://dx.doi.org/10.1002/cvde.201106978
• Related Public URLs: http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1521-3862