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Accurate localization of incidental findings on the computed tomography attenuation correction image

Thompson, JD; Hogg, P; Higham, S; Manning, D

Authors

JD Thompson

S Higham

D Manning



Abstract

This observer performance study assessed lesion
detection in the computed tomography attenuation
correction image, as would be produced for myocardial
perfusion imaging over a tube current (mA) range. A static
anthropomorphic chest phantom containing simulated
pulmonary lesions was scanned using the four available
mA values (1, 1.5, 2 and 2.5) on a GE Infinia Hawkeye 4.
All other computed tomography acquisition parameters
remained constant throughout. Twenty-seven cases
showing zero to four lesions were produced for a
free-response receiver-operating characteristic method.
Image observations were completed using our novel
web-based ROCView software under controlled conditions.
The Jackknife alternative free-response receiver-operating
characteristic (JAFROC) figure of merit was used for
significance testing, wherein a difference in lesion
detection performance was considered significant
at P values less than 0.05. Twenty readers with varying
computed tomography experience (0–24 years) evaluated
108 images using an ordinal scale to score confidence.
The JAFROC analysis showed that there was no
statistically significant difference in performance between
mA values (P= 0.439) for this sample of observers.
In conclusion, no significant difference in lesion detection
performance was seen between the mA values. This
suggests that there is no value in using anything other
than the lowest mA value for the investigation of incidental
extracardiac findings

Citation

Thompson, J., Hogg, P., Higham, S., & Manning, D. (2013). Accurate localization of incidental findings on the computed tomography attenuation correction image. Nuclear Medicine Communications, 34(2), 180-184. https://doi.org/10.1097/MNM.0b013e32835c0984

Journal Article Type Article
Publication Date Jan 1, 2013
Deposit Date Sep 12, 2014
Journal Nuclear Medicine Communications
Print ISSN 0143-3636
Publisher Lippincott, Williams & Wilkins
Volume 34
Issue 2
Pages 180-184
DOI https://doi.org/10.1097/MNM.0b013e32835c0984
Publisher URL http://dx.doi.org/10.1097/MNM.0b013e32835c0984