Dyspnoea-12 is a valid and reliable measure of breathlessness in patients with ILD

Yorke, J; Swigris, J; Russell, AM; Moosavi, SH; Man Ng Kwong, G; Longshaw, M; Jines, PW

Abstract

Objective: To determine the validity and reliability of the Dyspnoea-12 (D-12) for the assessment of breathlessness in patients with interstitial lung disease (ILD).

Methods: 101 patients with ILD completed the D-12 (scaling range 0-36, high score indicates worse dyspnea), MRC dyspnea scale, St George’s Respiratory Questionnaire (SGRQ), and Hospital anxiety and depression scale (HADS) at baseline, and 84 patients completed the D-12 and a global health transition score at follow-up 2-weeks later. D-12 psychometric properties, including floor and ceiling effects, internal consistency, test-retest reliability and construct validity of the D-12 were examined.

Results: The D-12 showed good internal consistency (Cronbach’s α =0.93) and repeatability (Intra-class correlation coefficient = 0.94). Its scores were significantly associated with MRC grade (r = 0.56, p<0.001), SGRQ (symptoms r = 0.57; activities r = 0.78; impacts r = 0.75; total r = 0.79, p<0.001). Confirmatory factor analysis confirmed the previously determined structure of the D-12 in this patient group.

Conclusion: In patients with ILD, the patient reported D-12 - a patient reported measure of dyspnoea severity that requires no reference to activity, is a reliable and valid instrument. It is short, simple to complete, and easy to score.

Copyright © 2010 American College of Chest Physicians

Citation

Yorke, J., Swigris, J., Russell, A., Moosavi, S., Man Ng Kwong, G., Longshaw, M., & Jines, P. (2011). Dyspnoea-12 is a valid and reliable measure of breathlessness in patients with ILD. Chest, 139(1), 159-164. https://doi.org/10.1378/chest.10-0693

• Journal Article Type: Article
• Publication Date: Jan 1, 2011
• Deposit Date: Jul 9, 2010
• Journal: Chest
• Print ISSN: 0012-3692
• Publisher: Elsevier
• Peer Reviewed: Peer Reviewed
• Volume: 139
• Issue: 1
• Pages: 159-164
• DOI: https://doi.org/10.1378/chest.10-0693
• Publisher URL: http://dx.doi.org/10.1378/chest.10-0693