Effects of obesity on cholesterol metabolism and its implications for healthy ageing

Mc Auley, Mark Tomás

Abstract

The last few decades have witnessed a global rise in the number of older individuals. Despite this demographic shift, morbidity within this population group is high. Many factors influence healthspan; however, an obesity pandemic is emerging as a significant determinant of older people’s health. It is well established that obesity adversely affects several metabolic systems. However, due to its close association with overall cardiometabolic health, the impact that obesity has on cholesterol metabolism needs to be recognised. The aim of the present review is to critically discuss the effects that obesity has on cholesterol metabolism and to reveal its significance for healthy ageing.

• Journal Article Type: Article
• Online Publication Date: Jan 27, 2020
• Publication Date: 2020-06
• Deposit Date: Feb 19, 2025
• Journal: Nutrition Research Reviews
• Print ISSN: 0954-4224
• Electronic ISSN: 1475-2700
• Publisher: Cambridge University Press (CUP)
• Peer Reviewed: Peer Reviewed
• Volume: 33
• Issue: 1
• Pages: 121-133
• DOI: https://doi.org/10.1017/s0954422419000258