Novel diarylamides and diarylureas with N-substitution dependent activity against medulloblastoma
(2021)
Journal Article
Lawson, C., Ahmed Alta, T., Moschou, G., Skamnaki, V., Solovou, T., Topham, C., …Snape, T. (2021). Novel diarylamides and diarylureas with N-substitution dependent activity against medulloblastoma. European Journal of Medicinal Chemistry, 225, 113751. https://doi.org/10.1016/j.ejmech.2021.113751
Medulloblastoma - highly aggressive and heterogeneous tumours of the cerebellum - account for 15-20% of all childhood brain tumours, and are the most common high-grade childhood embryonal tumour of the central nervous system. Herein, potent in vitro... Read More about Novel diarylamides and diarylureas with N-substitution dependent activity against medulloblastoma.