All Outputs (2)

Investigation of P53 and TTC5 function in lung cancer (2024)
Thesis
Menendez Creamer, D. P. (2024). Investigation of P53 and TTC5 function in lung cancer. (Thesis). University of Salford

Lung cancer represents 11.6% of the total cases with patients destined for a poor outcome due to late-stage detection, therefore it is important to find new approaches to detect and treat this disease. Current evidence suggests a role of p53 gene and... Read More about Investigation of P53 and TTC5 function in lung cancer.

Evaluation of the role of p53 tumour suppressor posttranslational modifications and TTC5 cofactor in lung cancer (2021)
Journal Article
Alhebshi, H., Tian, K., Patnaik, L., Taylor, R., Bezecny, P., Hall, C., …Krstic- Demonacos, M. (2021). Evaluation of the role of p53 tumour suppressor posttranslational modifications and TTC5 cofactor in lung cancer. International Journal of Molecular Sciences, 22(24), e13198. https://doi.org/10.3390/ijms222413198

Mutations in the p53 tumor suppressor are found in over 50% of cancers. p53 function is controlled through posttranslational modifications and cofactor interactions. In this study, we investigated the posttranslationally modified p53, including p53 a... Read More about Evaluation of the role of p53 tumour suppressor posttranslational modifications and TTC5 cofactor in lung cancer.