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All Outputs (26)

Characterization of a trypanosome from large yellow croaker (Larimichthys crocea), cage-cultured in seawater, in China (2025)
Journal Article

A significant outbreak of trypanosomosis occurred in farmed large yellow croaker (Larimichthys crocea) in Southeast China resulting in daily mortality rates, over 70 days, of up to 1 % with cumulative losses nearing 60 %. Despite the severity of the... Read More about Characterization of a trypanosome from large yellow croaker (Larimichthys crocea), cage-cultured in seawater, in China.

Revealing the progression and pathologic features of intraperitoneal infection of Trichomonas vaginalis in mice via parasite α-actinin-based immunological detection (2024)
Journal Article

Background: Trichomoniasis caused by Trichomonas vaginalis is the most prevalent nonviral sexually transmitted disease in women and has frequently damaged public health. To better use the animal model and take a step forward fully elucidating this pa... Read More about Revealing the progression and pathologic features of intraperitoneal infection of Trichomonas vaginalis in mice via parasite α-actinin-based immunological detection.

Multiomics of parkinsonism cynomolgus monkeys highlights significance of metabolites in interaction between host and microbiota (2024)
Journal Article

The gut microbiota has been demonstrated to play a significant role in the pathogenesis of Parkinson’s disease (PD). However, conflicting findings regarding specific microbial species have been reported, possibly due to confounding factors within hum... Read More about Multiomics of parkinsonism cynomolgus monkeys highlights significance of metabolites in interaction between host and microbiota.

First outbreak of trypanosomiasis in farmed blood parrot cichlids (Vieja melanura♀ × Amphilophus citrinellus♂) from southern China (2024)
Journal Article

Outbreaks of fish trypanosomiasis are regularly reported in cultured groupers (Epinephelus spp.), largemouth bass (Micropterus salmoides), and many other species of Cyprinidae, but only rarely reported in ornamental fish. This study reports a trypano... Read More about First outbreak of trypanosomiasis in farmed blood parrot cichlids (Vieja melanura♀ × Amphilophus citrinellus♂) from southern China.

The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival (2024)
Journal Article

The apicoplast is a four-membrane plastid found in the apicomplexans, which harbors biosynthesis and organelle housekeeping activities in the matrix. However, the mechanism driving the flux of metabolites, in and out, remains unknown. Here, we used T... Read More about The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival.

Prevalence of Eimeria Species, Detected by ITS1-PCR Immobilized on FTA Cards, in Future Laying Hens and Breeding Hens in Six Provinces in Northeastern Algeria (2024)
Journal Article

Purpose
Avian coccidiosis is an important and widely distributed disease that affects global agricultural economies through losses. In Algeria, there is limited epidemiological and ecological knowledge about this disease and this hinders implementat... Read More about Prevalence of Eimeria Species, Detected by ITS1-PCR Immobilized on FTA Cards, in Future Laying Hens and Breeding Hens in Six Provinces in Northeastern Algeria.

Functional screening reveals Toxoplasma prenylated proteins required for endocytic trafficking and rhoptry protein sorting (2023)
Journal Article

In the apicomplexans, endocytosed cargos (e.g., hemoglobin) are trafficked to a specialized organelle for digestion. This follows a unique endocytotic process at the micropore/cytostome in these parasites. However, the mechanism underlying endocytic... Read More about Functional screening reveals Toxoplasma prenylated proteins required for endocytic trafficking and rhoptry protein sorting.

PAG3 promotes the differentiation of bloodstream forms in Trypanosoma brucei and reveals the evolutionary relationship among the Trypanozoon trypanosomes (2022)
Journal Article

Introduction: Trypanosoma brucei, T. evansi and T. equiperdum are members of the subgenus Trypanozoon and are highly similar morphologically and genetically. The main differences between these three species are their differentiation patterns in the h... Read More about PAG3 promotes the differentiation of bloodstream forms in Trypanosoma brucei and reveals the evolutionary relationship among the Trypanozoon trypanosomes.

Prevalence of Eimeria species, detected by ITS1-PCR, in broiler poultry farms located in seven provinces of northeastern Algeria. (2022)
Journal Article

Coccidiosis is an important global chickens' disease which can cause serious economic losses in the poultry industry worldwide. Little is known about the extent of infection or diversity, of the causative agent Eimeria spp., in Algeria. A priority, t... Read More about Prevalence of Eimeria species, detected by ITS1-PCR, in broiler poultry farms located in seven provinces of northeastern Algeria..

Nile tilapia (Oreochromis niloticus) can be experimentally infected with both marine and freshwater fish trypanosomes. (2022)
Journal Article

Trypanosomes are haemoflagellates found in vertebrate species and many of them can cause death in infected hosts including fish and humans. With the development of high-density farming in marine and freshwater fish aquaculture systems, severe disease... Read More about Nile tilapia (Oreochromis niloticus) can be experimentally infected with both marine and freshwater fish trypanosomes..

iNOS is essential to maintain a protective Th1/Th2 response and the production of cytokines/chemokines against Schistosoma japonicum infection in rats (2022)
Journal Article

Humans and a wide range of mammals are generally susceptible to Schistosoma infection, while some rodents such as Rattus rats and Microtus spp are not. We previously demonstrated that inherent high expression levels of nitric oxide (NO), produced by... Read More about iNOS is essential to maintain a protective Th1/Th2 response and the production of cytokines/chemokines against Schistosoma japonicum infection in rats.

Transplantation of Gut Microbiota From High-Fat-Diet-Tolerant Cynomolgus Monkeys Alleviates Hyperlipidemia and Hepatic Steatosis in Rats. (2022)
Journal Article

Emerging evidence has been reported to support the involvement of the gut microbiota in the host's blood lipid and hyperlipidemia (HLP). However, there remains unexplained variation in the host's blood lipid phenotype. Herein a nonhuman primate HLP m... Read More about Transplantation of Gut Microbiota From High-Fat-Diet-Tolerant Cynomolgus Monkeys Alleviates Hyperlipidemia and Hepatic Steatosis in Rats..

Species identification and phylogenetic analysis of Leishmania isolated from patients, vectors and hares in the Xinjiang Autonomous Region, The People's Republic of China (2021)
Journal Article

Visceral leishmaniasis (VL) has been declared as one of the six major tropical diseases by the World Health Organization. This disease has been successfully controlled in China, except for some areas in the western region, such as the Xinjiang Autono... Read More about Species identification and phylogenetic analysis of Leishmania isolated from patients, vectors and hares in the Xinjiang Autonomous Region, The People's Republic of China.

A new species of mammalian trypanosome, Trypanosoma (Megatrypanum) bubalisi sp. nov., found in the freshwater leech Hirudinaria manillensis (2021)
Journal Article

Leeches have long been considered potential vectors for the aquatic lineage of trypanosomes, while bloodsucking insects are generally considered as the vectors for the terrestrial lineage of trypanosomes. The freshwater leech, Hirudinaria manillensis... Read More about A new species of mammalian trypanosome, Trypanosoma (Megatrypanum) bubalisi sp. nov., found in the freshwater leech Hirudinaria manillensis.