Schistosoma mansoni: egg-induced downregulation of hepatic stellate cell activation and fibrogenesis
(2010)
Journal Article
Anthony, B., Mathieson, W., de Castro-Borges, W., & Allen, J. (2010). Schistosoma mansoni: egg-induced downregulation of hepatic stellate cell activation and fibrogenesis. Experimental Parasitology, 124(4), 409-420. https://doi.org/10.1016/j.exppara.2009.12.009
Eggs of Schistosoma mansoni trapped in human liver can lead to fibrosis. Since liver fibrosis requires activation of hepatic stellate cells (HSC) from a quiescent to a myofibroblastic phenotype, we investigated the effects of S. mansoni eggs on this... Read More about Schistosoma mansoni: egg-induced downregulation of hepatic stellate cell activation and fibrogenesis.