All Outputs (2)

Fluorescent probe for detection of bacteria : conformational trigger upon bacterial reduction of an azo bridge (2012)
Journal Article
Rattray, N., Zalloum, W., Mansell, D., Latimer, J., Schwalbe, C., Blake, A., …Freeman, S. (2012). Fluorescent probe for detection of bacteria : conformational trigger upon bacterial reduction of an azo bridge. Chemical Communications, 48, 6393-6395. https://doi.org/10.1039/C2CC32521G

Using biomimetic chemical reduction or Clostridium perfringens cell extract containing azoreductase, the dimer-fluorescent probe 2,4-O-bisdansyl-6,7-diazabicyclooct-6-ene, which possesses a conformationally constrained cis-azo bridge, is reduced to t... Read More about Fluorescent probe for detection of bacteria : conformational trigger upon bacterial reduction of an azo bridge.

Attenuated Virulence and Biofilm Formation in Staphylococcus aureus following Sublethal Exposure to Triclosan (2012)
Journal Article
Latimer, J., Forbes, S., & McBain, A. (2012). Attenuated Virulence and Biofilm Formation in Staphylococcus aureus following Sublethal Exposure to Triclosan. Antimicrobial Agents and Chemotherapy, 56(6), 3092-3100. https://doi.org/10.1128/AAC.05904-11

Subeffective exposure of Staphylococcus aureus to the biocide triclosan can reportedly induce a small-colony variant (SCV) phenotype. S. aureus SCVs are characterized by low growth rates, reduced pigmentation, and lowered antimicrobial susceptibility... Read More about Attenuated Virulence and Biofilm Formation in Staphylococcus aureus following Sublethal Exposure to Triclosan.