All Outputs (2)

Anticancer phototherapy using activation of E-combretastatins by two-photon–induced isomerization (2014)
Journal Article
Hadfield, J., Bisby, R., Scherer, K., Botchway, S., & Parker, A. (2014). Anticancer phototherapy using activation of E-combretastatins by two-photon–induced isomerization. Journal of Biomedical Optics, 20(5), 1004-1. https://doi.org/10.1117/1.JBO.20.5.051004

The photoisomerization of relatively nontoxic E-combretastatins to clinically active Z-isomers is
shown to occur in solution through both one- and two-photon excitations at 340 and 625 nm, respectively.
The photoisomerization is also demonstrated t... Read More about Anticancer phototherapy using activation of E-combretastatins by two-photon–induced isomerization.

Spectroscopy and fluorescence lifetime imaging in live cells of a cyano-substituted combretastatin (2014)
Journal Article
combretastatin. Biomedical Spectroscopy and Imaging, 3, 211-218. https://doi.org/10.3233/BSI-140067

Fluorescence lifetime imaging has been used to observe the real-time uptake in live mammalian cells of a
combretastatin-type drug analogue that is a substituted stilbene with a cyano group at the bridging olefinic bond. Fluorescence spectra in a ran... Read More about Spectroscopy and fluorescence lifetime imaging in live cells of a cyano-substituted combretastatin.