All Outputs (3)

p53 modeling as a route to mesothelioma patients' stratification and novel therapeutic identification (2018)
Journal Article
Tian, K., Bakker, E., Hussain, M., Guazzelli, A., Alhebshi, H., Meysami, P., …Krstic-Demonacos, M. (2018). p53 modeling as a route to mesothelioma patients' stratification and novel therapeutic identification. Journal of Translational Medicine, 16(282), https://doi.org/10.1186/s12967-018-1650-0

Background: Malignant pleural mesothelioma (MPM) is an orphan disease that is difficult to treat using traditional chemotherapy, an approach which has been effective in other types of cancer. Most chemotherapeutics cause DNA damage leading to cell de... Read More about p53 modeling as a route to mesothelioma patients' stratification and novel therapeutic identification.

State of the art : concise review scientific advances and new frontiers in mesothelioma therapeutics (2018)
Journal Article
Mutti, L., Peikert, T., Robinson, B., Scherpereel, A., Tsao, A., de Perrot, M., …Hassan, R. (2018). State of the art : concise review scientific advances and new frontiers in mesothelioma therapeutics. Journal of Thoracic Oncology, 13(9), 1269-1283. https://doi.org/10.1016/j.jtho.2018.06.011

Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer that arises from the mesothelial surface of the pleural and peritoneal cavities, the pericardium, and rarely, the tunica vaginalis. The incidence of MPM is expected to increase worl... Read More about State of the art : concise review scientific advances and new frontiers in mesothelioma therapeutics.

Surgery for malignant pleural mesothelioma : an international guidelines review (2018)
Journal Article
Ricciardi, S., Cardillo, G., Zirafa, C., Carleo, F., Facciolo, F., Fontanini, G., …Melfi, F. (2018). Surgery for malignant pleural mesothelioma : an international guidelines review. Journal of thoracic disease, 10(Supp.2), S285-S292. https://doi.org/10.21037/jtd.2017.10.16

Currently there is no universally accepted surgical therapy for malignant pleural mesothelioma (MPM). The goal of surgery in this dismal disease is a macroscopic complete resection (MCR) and there are two types of intervention with a curative intent.... Read More about Surgery for malignant pleural mesothelioma : an international guidelines review.