All Outputs (2)

Bio-inspired artemether loaded human serum albumin nanoparticles for effective control of malaria-infected erythrocytes (2016)
Journal Article
Sidhaye, A., Bhuran, K., Zambare, S., Abubaker, M., Nirmalan, N., & Singh, K. (2016). Bio-inspired artemether loaded human serum albumin nanoparticles for effective control of malaria-infected erythrocytes. Nanomedicine, 11(21), 2809-2828. https://doi.org/10.2217/nnm-2016-0235

Background: The intra-erythrocytic development of the malarial parasite is dependent on active uptake of nutrients, including human serum albumin(HSA), into parasitized erythrocytes(pRBCs). We have designed HSA-based nanoparticles as a potential drug... Read More about Bio-inspired artemether loaded human serum albumin nanoparticles for effective control of malaria-infected erythrocytes.

“Omics”-Informed drug and biomarker discovery : opportunities, challenges and future perspectives (2016)
Journal Article
Matthews, H., Hanison, J., & Nirmalan, N. (2016). “Omics”-Informed drug and biomarker discovery : opportunities, challenges and future perspectives. Proteomes, 4(3), 28. https://doi.org/10.3390/proteomes4030028

The pharmaceutical industry faces unsustainable program failure despite significant increases in investment. Dwindling discovery pipelines, rapidly expanding R&D budgets and increasing regulatory control, predict significant gaps in the future drug m... Read More about “Omics”-Informed drug and biomarker discovery : opportunities, challenges and future perspectives.