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Plasma interleukin responses as predictors of outcome stratification in patients after major trauma: a prospective observational two centre study (2023)
Journal Article
Jones, M. A., Hanison, J., Apreutesei, R., Allarakia, B., Namvar, S., Ramaswamy, D. S., …Nirmalan, N. (2023). Plasma interleukin responses as predictors of outcome stratification in patients after major trauma: a prospective observational two centre study. Frontiers in Immunology, 14, 1276171. https://doi.org/10.3389/fimmu.2023.1276171

Background and objectives: There is a need to develop objective risk stratification tools to define efficient care pathways for trauma patients. Biomarker-based point of care testing may strengthen existing clinical tools currently available for this... Read More about Plasma interleukin responses as predictors of outcome stratification in patients after major trauma: a prospective observational two centre study.

Evaluation of 4-Aminoquinoline Hydrazone Analogues as Potential Leads for Drug-Resistant Malaria (2023)
Journal Article
Magwaza, R. N., Abubaker, M., Hussain, B., Haley, M., Couper, K., Freeman, S., & Nirmalan, N. J. (in press). Evaluation of 4-Aminoquinoline Hydrazone Analogues as Potential Leads for Drug-Resistant Malaria. Molecules, 28(18), 6471. https://doi.org/10.3390/molecules28186471

The emergence of resistance to first-line antimalarial drugs calls for the development of new therapies for drug-resistant malaria. The efficacy of quinoline-based antimalarial drugs has prompted the development of novel quinolines. A panel of 4-amin... Read More about Evaluation of 4-Aminoquinoline Hydrazone Analogues as Potential Leads for Drug-Resistant Malaria.