All Outputs (22)

Obesity-related perivascular adipose tissue damage is reversed by sustained weight loss in the rat (2016)
Journal Article
Bussey, C., Withers, S., Aldous, R., Edwards, G., & Heagerty, A. (2016). Obesity-related perivascular adipose tissue damage is reversed by sustained weight loss in the rat. Arteriosclerosis, Thrombosis, and Vascular Biology, 36(7), 1377-1385. https://doi.org/10.1161/ATVBAHA.116.307210

Objective – Perivascular adipose tissue (PVAT) exerts an anticontractile effect in response to various vasoconstrictor agonists and this is lost in obesity. A recent study reported that bariatric surgery reverses the damaging effects of obesity on PV... Read More about Obesity-related perivascular adipose tissue damage is reversed by sustained weight loss in the rat.

Mechanisms of adiponectin-associated perivascular function in vascular disease (2014)
Journal Article
Withers, S., Bussey, C., Saxton, S., Melrose, H., Watkins, A., & Heagerty, A. (2014). Mechanisms of adiponectin-associated perivascular function in vascular disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 34(8), 1637-42. https://doi.org/10.1161/ATVBAHA.114.303031

The concept that fat cells could influence the circulation and indeed cardiac function has been in existence for ≥20 years and has gained a wide interest and no less excitement as evidence has accrued to suggest that such effects may be profound enou... Read More about Mechanisms of adiponectin-associated perivascular function in vascular disease.