Studies on the effect of asparaginase in paediatric leukaemia
(2010)
Thesis
Coe, N. Studies on the effect of asparaginase in paediatric leukaemia. (Thesis). Salford : University of Salford
Asparaginase, an important agent in the treatment of acute lymphoblastic leukaemia, is thought to cause cell death by depriving lymphoblasts of asparagine. However, because asparaginase also hydrolyses glutamine, a critical fuel for normal lymphoc... Read More about Studies on the effect of asparaginase in paediatric leukaemia.