All Outputs (418)

Bistable Helmholtz dark spatial optical solitons in materials with self-defocusing saturable nonlinearity (2017)
Journal Article
Christian, J., & Lundie, M. (2017). Bistable Helmholtz dark spatial optical solitons in materials with self-defocusing saturable nonlinearity. Journal of Nonlinear Optical Physics and Materials, 26(02), https://doi.org/10.1142/S0218863517500242

We present, to the best of our knowledge, the first exact dark spatial solitons of a nonlinear Helmholtz equation with a self-defocusing saturable refractive-index model. These solutions capture oblique (arbitrary-angle) propagation in both the forwa... Read More about Bistable Helmholtz dark spatial optical solitons in materials with self-defocusing saturable nonlinearity.

Finite element computation of transient dissipative double diffusive magneto-convective nanofluid flow from a rotating vertical porous surface in porous media (2017)
Journal Article
Beg, O., Thumma, T., & Sheri, S. (2017). Finite element computation of transient dissipative double diffusive magneto-convective nanofluid flow from a rotating vertical porous surface in porous media. Proceedings of the Institution of Mechanical Engineers, Part N: Journal of Nanomaterials, Nanoengineering and Nanosystems, 231(2), 89-108. https://doi.org/10.1177/2397791417712856

This paper aimed to investigate the transient dissipative MHD double diffusive free convective boundary layer flow of electrically-conducting nanofluids from a stationary or moving vertical porous surface in a rotating high permeability porous medium... Read More about Finite element computation of transient dissipative double diffusive magneto-convective nanofluid flow from a rotating vertical porous surface in porous media.

Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques (2017)
Journal Article
Denbigh, J., Perez-Guaita, D., Vernooij, R., Tobin, M., Bambery, K., Xu, Y., …Wood, B. (2017). Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques. Scientific reports, 7(1), 2649. https://doi.org/10.1038/s41598-017-02069-5

Acute myeloid leukaemia (AML) is a life threatening cancer for which there is an urgent clinical need for novel therapeutic approaches. A redeployed drug combination of bezafibrate and medroxyprogesterone acetate (BaP) has shown anti-leukaemic activi... Read More about Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques.

A Mathematical Model of a Conceptual Design Approach of High Altitude Solar Powered Unmanned Aerial Vehicles (2017)
Journal Article
Alsahlani, A., & Rahulan, T. (2017). A Mathematical Model of a Conceptual Design Approach of High Altitude Solar Powered Unmanned Aerial Vehicles. https://doi.org/10.15866/irease.v10i4.11774

In this paper, an analytical approach has been developed to design a high altitude solar-powered aircraft, for a given mission at a conceptual design stage. The mass and power of each aircraft component are estimated as a constant fraction of either... Read More about A Mathematical Model of a Conceptual Design Approach of High Altitude Solar Powered Unmanned Aerial Vehicles.

The influence of culture, beliefs and experience on the sustainable end-of-life management of buildings in Nigeria (2017)
Journal Article
Abdullahi, A., & Lee, A. (2017). The influence of culture, beliefs and experience on the sustainable end-of-life management of buildings in Nigeria. Journal of construction project management and innovation, 7(1), 1793-1806

While it is usually believed that economic incentives are behind waste management practices in developing countries, this article discusses culture, belief and experience as the other major influences in the management practices of building demolitio... Read More about The influence of culture, beliefs and experience on the sustainable end-of-life management of buildings in Nigeria.

Hodgkin lymphoma : a complex metabolic ecosystem with glycolytic reprogramming of the tumor microenvironment (2017)
Journal Article
Mikkilineni, L., Whitaker-Menezes, D., Domingo-Vidal, M., Sprandio, J., Avena, P., Cotzia, P., …Martinez-Outschoorn, U. (2017). Hodgkin lymphoma : a complex metabolic ecosystem with glycolytic reprogramming of the tumor microenvironment. Seminars in Oncology, 44(3), 218-225. https://doi.org/10.1053/j.seminoncol.2017.10.003

Background Twenty percent of patients with classical Hodgkin Lymphoma (cHL) have aggressive disease defined as relapsed or refractory disease to initial therapy. At present we cannot identify these patients pre-treatment. The microenvironment is v... Read More about Hodgkin lymphoma : a complex metabolic ecosystem with glycolytic reprogramming of the tumor microenvironment.

Quantifying and filtering knowledge generated by literature based discovery (2017)
Journal Article
Preiss, J., & Stevenson, M. (2017). Quantifying and filtering knowledge generated by literature based discovery. BMC Bioinformatics, 18(Sup. 7), 249. https://doi.org/10.1186/s12859-017-1641-9

Background Literature based discovery (LBD) automatically infers missed connections between concepts in literature. It is often assumed that LBD generates more information than can be reasonably examined. Methods We present a detailed analysis o... Read More about Quantifying and filtering knowledge generated by literature based discovery.

Improving productivity of road surfacing operations using value stream mapping and discrete event simulation (2017)
Journal Article
Qasim, R., Aziz, Z., & Wajdi, S. (2017). Improving productivity of road surfacing operations using value stream mapping and discrete event simulation. Construction innovation (London. Online), 17(3), 294-323. https://doi.org/10.1108/CI-11-2016-0058

The Highways Infrastructure is one of the most valuable asset owned by the public sector. Efficient operations of Highways have the success of national and local economies as well as the quality of life of the general public, dependent on it. Ensurin... Read More about Improving productivity of road surfacing operations using value stream mapping and discrete event simulation.

An Amazonian rainforest and its fragments as a laboratory of global change (2017)
Journal Article
Laurance, W., Camargo, J., Fearnside, P., Lovejoy, T., Williamson, B., Mesquita, R., …Laurance, S. (2017). An Amazonian rainforest and its fragments as a laboratory of global change. Biological Reviews, 93(1), 223-247. https://doi.org/10.1111/brv.12343

We synthesize findings from one of the world’s largest and longest-running experimental investigations, the Biological Dynamics of Forest Fragments Project (BDFFP). Spanning an area of ~1,000 km2 in central Amazonia, the BDFFP was initially designed... Read More about An Amazonian rainforest and its fragments as a laboratory of global change.

Influence of size and shape on the anatomical distribution of endotoxin-free gold nanoparticles (2017)
Journal Article
Talamini, L., Violato, M. B., Cai, Q., Monopoli, M., Kantner, K., Krpetic, Z., …Bigini, P. (2017). Influence of size and shape on the anatomical distribution of endotoxin-free gold nanoparticles. ACS nano, 11(6), 5519-5529. https://doi.org/10.1021/acsnano.7b00497

The transport and the delivery of drugs through nanocarriers is a great challenge of pharmacology. Since the production of liposomes to reduce the toxicity of doxorubicin in patients, a plethora of nanomaterials have been produced and characterized.... Read More about Influence of size and shape on the anatomical distribution of endotoxin-free gold nanoparticles.

The thermal performance of window coverings in a whole house test facility with single-glazed sash windows (2017)
Journal Article
Fitton, R., Swan, W., Hughes, T., & Benjaber, M. (2017). The thermal performance of window coverings in a whole house test facility with single-glazed sash windows. Energy Efficiency, 10(6), 1419-1431. https://doi.org/10.1007/s12053-017-9529-0

The residential sector is responsible for 29% of the total energy consumption of the UK, with 62% of this energy being used for space heating. Heat loss through the fabric of building elements is a crucial factor in the energy efficiency of homes, an... Read More about The thermal performance of window coverings in a whole house test facility with single-glazed sash windows.

Dual functionality anti-reflection and biocidal coatings (2017)
Journal Article
Yates, H., Sheel, P., Hodgkinson, J., Warwick, M., Elfakhri, S., & Foster, H. (2017). Dual functionality anti-reflection and biocidal coatings. Surface and Coatings Technology, 324, 201-207. https://doi.org/10.1016/j.surfcoat.2017.05.077

A thin film combination of anti-reflection (AR) and biocidal properties would be of particular interest to reduce the transfer of infection and improve readability of public high use touch screens. In this paper we describe the development of a dual... Read More about Dual functionality anti-reflection and biocidal coatings.

A-to-I editing in human miRNAs is enriched in seed sequence, influenced by sequence contexts and significantly hypoedited in glioblastoma multiforme (2017)
Journal Article
Paul, D., Sinha, A., Ray, A., Lal, M., Nayak, S., Sharma, A., …Mukhopadhyay, A. (2017). A-to-I editing in human miRNAs is enriched in seed sequence, influenced by sequence contexts and significantly hypoedited in glioblastoma multiforme. Scientific reports, 7(2466), https://doi.org/10.1038/s41598-017-02397-6

Editing in microRNAs, particularly in seed can significantly alter the choice of their target genes. We show that out of 13 different human tissues, different regions of brain showed higher adenosine to inosine (A-to-I) editing in mature miRNAs. Thes... Read More about A-to-I editing in human miRNAs is enriched in seed sequence, influenced by sequence contexts and significantly hypoedited in glioblastoma multiforme.

The effect of pavement characteristics on pedestrians' thermal comfort in Toronto (2017)
Journal Article
Taleghani, M., & Berardi, U. (2017). The effect of pavement characteristics on pedestrians' thermal comfort in Toronto. Urban Climate, 24, 449-459. https://doi.org/10.1016/j.uclim.2017.05.007

Urban heat island (UHI) has proved to have an important effect in urban microclimate of large cities. In particular, the materials used for the pavements of urban spaces and sidewalks affect pedestrians' comfort significantly. Dark materials store so... Read More about The effect of pavement characteristics on pedestrians' thermal comfort in Toronto.

The inhibition of FGF receptor 1 activity mediates sorafenib-induced antiproliferative effects in human mesothelioma tumor-initiating cells (2017)
Journal Article
Pattarozzi, A., Carra, E., Favoni, R., Würth, R., Marubbi, D., Filiberti, R., …Daga, A. (2017). The inhibition of FGF receptor 1 activity mediates sorafenib-induced antiproliferative effects in human mesothelioma tumor-initiating cells. Stem Cell Research and Therapy, 8(119), https://doi.org/10.1186/s13287-017-0573-7

Tumor-initiating cells (TICs), the subset of cells within tumors endowed with stem-like features, being highly resistant to conventional cytotoxic drugs, are the major cause of tumor relapse. The identification of molecules able to target TICs remain... Read More about The inhibition of FGF receptor 1 activity mediates sorafenib-induced antiproliferative effects in human mesothelioma tumor-initiating cells.

Current and prospective pharmacotherapies for the treatment of pleural mesothelioma (2017)
Journal Article
Bakker, E., Guazzelli, A., Krstic-Demonacos, M., Lisanti, M., Sotgia, F., & Mutti, L. (2017). Current and prospective pharmacotherapies for the treatment of pleural mesothelioma. Expert Opinion on Orphan Drugs, 5(6), 455-465. https://doi.org/10.1080/21678707.2017.1325358

Introduction: Mesothelioma is a rare asbestos-linked cancer with an expected incidence peak between 2015–2030. Therapies remain ineffective, thus developing and testing novel treatments is important for both oncologists and researchers. Areas co... Read More about Current and prospective pharmacotherapies for the treatment of pleural mesothelioma.

Comparison of experimental ponds for the treatment of dye wastewater under controlled and semi-natural conditions (2017)
Journal Article
Yaseen, D., & Scholz, M. (2017). Comparison of experimental ponds for the treatment of dye wastewater under controlled and semi-natural conditions. Environmental Science and Pollution Research, 24(19), 16031-16040. https://doi.org/10.1007/s11356-017-9245-5

This study compares the performance of simulated shallow ponds vegetated with Lemna minor L. under controlled and semi-natural conditions for the treatment of simulated wastewater containing textile dyes. The objectives were to assess the water quali... Read More about Comparison of experimental ponds for the treatment of dye wastewater under controlled and semi-natural conditions.

Electrothermal transport in biological systems : an analytical approach for electrokinetically-modulated peristaltic flow (2017)
Journal Article
Tripathi, D., Sharma, A., Beg, O., & Tiwari, A. (2017). Electrothermal transport in biological systems : an analytical approach for electrokinetically-modulated peristaltic flow. Journal of Thermal Science and Engineering Applications, 9(4), https://doi.org/10.1115/1.4036803

A mathematical model is developed to investigate the combined viscous electro-osmotic flow and heat transfer in a finite length micro-channel with peristaltic wavy walls. The influence of Joule heating is included. The unsteady two-dimensional conser... Read More about Electrothermal transport in biological systems : an analytical approach for electrokinetically-modulated peristaltic flow.

CFD investigation of indoor hygrothermal performance in academic research storage room : measurement and validation (2017)
Journal Article
Oladokun, M., Ali, M., Bahrin Osman, S., Samsuddin, N., Hamzah, H., & Salleh, M. (2017). CFD investigation of indoor hygrothermal performance in academic research storage room : measurement and validation. Journal of engineering and applied sciences (Asian Research Publishing Network), 12(10), 3130-3136

Poor hygrothermal performance exacerbates deterioration risk from mould growth, corrosion and damage to archival materials. Improved microcomputers’ computational power has significantly advanced computational fluid dynamics (CFD) models and resear... Read More about CFD investigation of indoor hygrothermal performance in academic research storage room : measurement and validation.

Mesothelin promoter variants are associated with increased soluble mesothelin-related peptide levels in asbestos-exposed individuals (2017)
Journal Article
De Santi, C., Pucci, P., Bonotti, A., Melaiu, O., Cipollini, M., Silvestri, R., …Landi, S. (2017). Mesothelin promoter variants are associated with increased soluble mesothelin-related peptide levels in asbestos-exposed individuals. Occupational and Environmental Medicine, 74(6), 457-464. https://doi.org/10.1136/oemed-2016-104024

BACKGROUND: Soluble mesothelin-related peptide (SMRP) is a promising diagnostic biomarker for malignant pleural mesothelioma (MPM), but various confounders hinder its usefulness in surveillance programmes. We previously showed that a single nucleoti... Read More about Mesothelin promoter variants are associated with increased soluble mesothelin-related peptide levels in asbestos-exposed individuals.