All Outputs (3)

Expression status of candidate genes in mesothelioma tissues and cell lines (2014)
Journal Article
Melaiu, O., Melissari, E., Mutti, L., Bracci, E., De Santi, C., Iofrida, C., …Landi, S. (2015). Expression status of candidate genes in mesothelioma tissues and cell lines. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 771, 6-12. https://doi.org/10.1016/j.mrfmmm.2014.11.002

In order to broaden knowledge on the pathogenesis of malignant pleural mesothelioma (MPM), we reviewed studies on the MPM-transcriptome and identified 119 deregulated genes. However, there was poor consistency among the studies. Thus, the expression... Read More about Expression status of candidate genes in mesothelioma tissues and cell lines.

A common polymorphism within MSLN Affects miR-611 binding site and soluble mesothelin levels in healthy people (2014)
Journal Article
Garritano, S., De Santi, C., Silvestri, R., Melaiu, O., Cipollini, M., Barone, E., …Landi, S. (2014). A common polymorphism within MSLN Affects miR-611 binding site and soluble mesothelin levels in healthy people. Journal of Thoracic Oncology, 9(11), 1662-1668. https://doi.org/10.1097/JTO.0000000000000322

INTRODUCTION: Soluble mesothelin related peptide (SMRP) was proposed as a promising diagnostic marker for malignant pleural mesothelioma (MPM). In a previous study, we found that rs1057147 within the 3' untranslated region of MSLN gene was associat... Read More about A common polymorphism within MSLN Affects miR-611 binding site and soluble mesothelin levels in healthy people.

MSLN gene silencing has an anti-malignant effect on cell lines overexpressing mesothelin deriving from malignant pleural mesothelioma (2014)
Journal Article
Ho, M., Melaiu, O., Stebbing, J., Lombardo, Y., Bracci, E., Uehara, N., …Landi, S. (2014). MSLN gene silencing has an anti-malignant effect on cell lines overexpressing mesothelin deriving from malignant pleural mesothelioma. PLoS ONE, 9(1), e85935. https://doi.org/10.1371/journal.pone.0085935

Genes involved in the carcinogenetic mechanisms underlying malignant pleural mesothelioma (MPM) are still poorly characterized. So far, mesothelin (MSLN) has aroused the most interest. It encodes for a membrane glycoprotein, frequently over-expressed... Read More about MSLN gene silencing has an anti-malignant effect on cell lines overexpressing mesothelin deriving from malignant pleural mesothelioma.