All Outputs (2)

The integrative multi-omics approach identifies the novel competing endogenous RNA (ceRNA) network in colorectal cancer (2023)
Journal Article

Circular RNAs (circRNA) are known to function as competing endogenous RNA (ceRNA) in various cancers by regulating microRNAs (miRNA). However, in colorectal cancer (CRC), the precise pathological role of circ000240/miRNA/mRNA remains indeterminate. T... Read More about The integrative multi-omics approach identifies the novel competing endogenous RNA (ceRNA) network in colorectal cancer.

Structure-based small inhibitors search combined with molecular dynamics driven energies for human programmed cell death-1 (PD-1) protein (2023)
Journal Article
Waqas, M., Halim, S. A., Alsalman, A., Khan, A., Elkord, E., & Al-Harrasi, A. (2023). Structure-based small inhibitors search combined with molecular dynamics driven energies for human programmed cell death-1 (PD-1) protein. Journal of Biomolecular Structure and Dynamics, 41(24), 14771-14785. https://doi.org/10.1080/07391102.2023.2188958

Human immune system is specialized in distinguishing normal cells from foreign particles mainly through proteins expressed on immune cells called ‘checkpoints’. Immune checkpoints work as a switch to activate and deactivate immune responses. T cells... Read More about Structure-based small inhibitors search combined with molecular dynamics driven energies for human programmed cell death-1 (PD-1) protein.