All Outputs (54)

Investigating the use of t-lymphocyte and cytokine biomarkers to predict clinical outcomes of major trauma patients (2024)
Thesis
Edirisinghe, N. Investigating the use of t-lymphocyte and cytokine biomarkers to predict clinical outcomes of major trauma patients. (Thesis). University of Salford

Trauma remains a leading cause of morbidity and mortality globally with a significant burden across the globe irrespective of socio-economic levels. In the UK, major trauma (MT) as a result of motor vehicle accidents is the leading cause of death in... Read More about Investigating the use of t-lymphocyte and cytokine biomarkers to predict clinical outcomes of major trauma patients.

The Role Of Interleukin-1β In Coronary Artery Disease (2024)
Thesis
Pearson, L. The Role Of Interleukin-1β In Coronary Artery Disease. (Thesis). University of Salford

Coronary artery disease (CAD) is a leading cause of mortality worldwide, with an estimated 17.8 million CAD-associated deaths each year. A prominent pathogenic factor in CAD is inflammation, which is associated with elevated levels of the cytokine in... Read More about The Role Of Interleukin-1β In Coronary Artery Disease.

12 Years On Assessment Of The Release Rehabilitation Program Of Yucatan Black Howler Monkeys Alouatta Pigra In The Northeastern Biological Corridor Of Belize Pdf (2024)
Thesis

Long-term monitoring of animals that have undergone wildlife rehabilitation is crucial to assess their long-term survival and adaptation after release. This study evaluates a primate rehabilitation centre in Belize, with a focus on the 78 Yucatán bla... Read More about 12 Years On Assessment Of The Release Rehabilitation Program Of Yucatan Black Howler Monkeys Alouatta Pigra In The Northeastern Biological Corridor Of Belize Pdf.

In vitro and in vivo evaluation of the effect of Aspergillus fumigatus on epithelial cells. (2024)
Thesis

Aspergillus fumigatus is a saprophytic fungus and one of the most prevalent airborne pathogens. Asthma is severe and associated with increased mortality in those patients that have fungal sensitisation. Mechanisms of airway wall remodelling and the p... Read More about In vitro and in vivo evaluation of the effect of Aspergillus fumigatus on epithelial cells..

Towards Energy Recovery from Waste in Developing Countries An Analysis of the Challenges, Barriers and Prospects of Waste Management in Abuja, Nigeria (2024)
Thesis

Waste management is a pressing global concern with far-reaching environmental,
social, and economic implications. Proper waste management is crucial for
sustainable development and achieving a cleaner environment. Studies have
projected that the a... Read More about Towards Energy Recovery from Waste in Developing Countries An Analysis of the Challenges, Barriers and Prospects of Waste Management in Abuja, Nigeria.

The Role of Tumour Necrosis Factor-α in Coronary Artery Disease (2024)
Thesis

Coronary artery disease (CAD) is a chronic inflammatory condition associated with high rates
of mortality worldwide. Pro-inflammatory cytokines such as tumour necrosis factor (TNFα)
play a key role in CAD pathogenesis, though the degree to which TN... Read More about The Role of Tumour Necrosis Factor-α in Coronary Artery Disease.

Simple models for complicated epidemics: Epidemiologically-based surveillance for early detection of invading plant diseases (2024)
Thesis

Plant disease epidemiology is the study of plant pests and their related diseases in populations of plants over time and space. In plant disease epidemiology, mathematical and computer simulation modelling is often deployed to provide insight into th... Read More about Simple models for complicated epidemics: Epidemiologically-based surveillance for early detection of invading plant diseases.

Vertical Greening and its Implementation in the Semi-Arid Region of Northern Nigeria  (2024)
Thesis

Climate change continues to be a global concern, necessitating sustainable environmental approaches to mitigate its impact. The United Nations’ Sustainable Development Goals (SDGs) aim to address these challenges by 2030, by reducing greenhouse gas e... Read More about Vertical Greening and its Implementation in the Semi-Arid Region of Northern Nigeria .

The Impact of Land Use and Land Cover Change on Flooding along Epie Creek, Nigeria: A Multi-Stakeholder Approach. (2024)
Thesis

Flooding is becoming more severe due to changes in land use and the effects of climate change, posing a serious environmental threat to tropical developing countries like Nigeria. Nigeria's unique characteristics, including rapid population growth, u... Read More about The Impact of Land Use and Land Cover Change on Flooding along Epie Creek, Nigeria: A Multi-Stakeholder Approach..

Development of Cybersecurity Framework for FinTech: Bahrain as a Case Study (2024)
Thesis

For decades, the Kingdom of Bahrain has embraced the changes brought by technology through
its commitment to further increase dynamism, creativity, and innovation. With the support of
its business-empowering regulations, Bahrain strives to establ... Read More about Development of Cybersecurity Framework for FinTech: Bahrain as a Case Study.

The invasion of the greater white toothed shrew, to Ireland, and its effects on the parasitic prevalence in the native pygmy shrew  (2024)
Thesis

The invasive greater white-toothed shrew (Crocidura russula) was first recorded in Ireland in
2007, where its range has since expanded at an alarming rate and caused the displacement
of the native pygmy shrew (Sorex minutus). As well as displacing... Read More about The invasion of the greater white toothed shrew, to Ireland, and its effects on the parasitic prevalence in the native pygmy shrew .

Environmental Justice and Private Urban Gardens: A Critical Analysis of Practices in Salford, Greater Manchester (2024)
Thesis

While it is well accepted that the quality of a greenspace determines its ability to provide health and
wellbeing benefits, research and policy overlook the spaces which residents have their most direct
and frequent contact with nature – urban hous... Read More about Environmental Justice and Private Urban Gardens: A Critical Analysis of Practices in Salford, Greater Manchester.

Investigation of P53 and TTC5 function in lung cancer (2024)
Thesis

Lung cancer represents 11.6% of the total cases with patients destined for a poor outcome due to late-stage detection, therefore it is important to find new approaches to detect and treat this disease. Current evidence suggests a role of p53 gene and... Read More about Investigation of P53 and TTC5 function in lung cancer.

Developing a framework and understanding the key influencing factors for the implementation of the Internet of Things (IoT) in the UK Construction Sector. (2024)
Thesis

The construction industry can be identified as one of the least digitized industries in the world,
drastically underperforming less in terms of profitability, productivity, reliability, efficiency, and
safety in comparison to the global economy tha... Read More about Developing a framework and understanding the key influencing factors for the implementation of the Internet of Things (IoT) in the UK Construction Sector..

Development of a novel and versatile synthesis for a potentially therapeutic di-aryl-alkylamine and related analogues (2024)
Thesis

Fendiline is an obsolete ion channel inhibitor originally prescribed as an anti-hypertensive medicine. However, recent repurposing has shown promising efficacy towards a range of serious ailments, most notably carcinomas including pancreatic and colo... Read More about Development of a novel and versatile synthesis for a potentially therapeutic di-aryl-alkylamine and related analogues.

Investigation Into The Potential Antimicrobial Properties Of Metal MADDR (2024)
Thesis

An exploration of the measured and modelled thermal characteristics of structural thermal breaks in UK buildings (2024)
Thesis

This research explores the measured and modelled thermal characteristics of structural thermal breaks (STBs) in UK buildings. Thermal bridging (TB) in building envelopes can significantly affect the fabric heat loss of a building, leading to higher e... Read More about An exploration of the measured and modelled thermal characteristics of structural thermal breaks in UK buildings.

Modelling Community Disaster Resilience: A Participatory Approach (2024)
Thesis

Due to the increasingly complex nature of climate change impacts, decision-makers such as local government practitioners and community members need more inclusive tools to assess their communities' resilience to environmental risks and natural hazard... Read More about Modelling Community Disaster Resilience: A Participatory Approach.

Targeting Transcriptional CDKs in Medulloblastoma (2024)
Thesis

Medulloblastoma (MB) is the most common malignant tumour of the brain in children. Current treatments include surgery, radiotherapy and chemotherapy. Although the five-year survival rate is over 70%, the treatment is exceptionally aggressive, leaving... Read More about Targeting Transcriptional CDKs in Medulloblastoma.

Optimizing Pandemic Control Strategies: A Deep Reinforcement Learning Approach in Public Health Management (2024)
Thesis

COVID-19, also known as the SARS-CoV-2 coronavirus, has paralysed the world and
forced people to change their lifestyles. Since COVID-19 deaths are increasing daily, the
disease has become a global public health issue. Different countries used diff... Read More about Optimizing Pandemic Control Strategies: A Deep Reinforcement Learning Approach in Public Health Management.