Skip to main content

Research Repository

Advanced Search

Outputs (42)

Detection and Identification of Microplastics in Freshwater Samples and their Toxicological Impact on Daphnia Pulex, A Model Organism for Freshwater (2024)
Thesis
Sana, A. (2024). Detection and Identification of Microplastics in Freshwater Samples and their Toxicological Impact on Daphnia Pulex, A Model Organism for Freshwater. (Thesis). University of Salford

Plastics have become an indispensable part of modern life due to their exceptional characteristics and versatility. Their use spans across various industries. At the beginning of plastic industry, the GPP was around 2 million tons, which reached a... Read More about Detection and Identification of Microplastics in Freshwater Samples and their Toxicological Impact on Daphnia Pulex, A Model Organism for Freshwater.

Enhanced Activity and Stability of an Acetyl Xylan Esterase in Hydrophilic Alcohols through Site-Directed Mutagenesis (2023)
Journal Article
Madubuike, H., & Ferry, N. (in press). Enhanced Activity and Stability of an Acetyl Xylan Esterase in Hydrophilic Alcohols through Site-Directed Mutagenesis. Molecules, 28(21), 7393. https://doi.org/10.3390/molecules28217393

Current demands for the development of suitable biocatalysts showing high process performance is stimulated by the need to replace current chemical synthesis with cleaner alternatives. A drawback to the use of biocatalysts for unique applications is... Read More about Enhanced Activity and Stability of an Acetyl Xylan Esterase in Hydrophilic Alcohols through Site-Directed Mutagenesis.

Characterisation and biochemical activity testing of CE1 and GH78 family enzymes; towards improved glycosyl hydrolases for the production of biofuel and biobased products (2022)
Thesis
Austin, S. Characterisation and biochemical activity testing of CE1 and GH78 family enzymes; towards improved glycosyl hydrolases for the production of biofuel and biobased products. (Thesis). University of Salford

Traditional chemical industries currently involved in the manufacturing and processing of high-value molecules used in the food, pharmaceutical and biofuel sector rely heavily on chemicals derived from fossil fuels such as crude oil. Fossil fuels rep... Read More about Characterisation and biochemical activity testing of CE1 and GH78 family enzymes; towards improved glycosyl hydrolases for the production of biofuel and biobased products.

Identification and characterisation of lignin degrading bacteria and enzymes from larval guts of the African Palm Weevil (Rhynchophorus phoenicis) (2022)
Thesis
larval guts of the African Palm Weevil (Rhynchophorus phoenicis). (Thesis). University of Salford

As developing economies continue to grow, the world’s demand for energy which currently stands at 84MB (million barrels oil) per day is projected to rise to 116 MB per day by the year 2030. The need to meet this continuous rise in demand for energy w... Read More about Identification and characterisation of lignin degrading bacteria and enzymes from larval guts of the African Palm Weevil (Rhynchophorus phoenicis).

Bioprospecting novel hemicellulases from the gut microbiota of the common black slug (Arion ater) (2022)
Thesis
Madubuike, H. Bioprospecting novel hemicellulases from the gut microbiota of the common black slug (Arion ater). (Thesis). University of Salford

The attendant effect of continuous fossil use on the environment and energy security has prompted the search for a suitable energy alternative devoid of negative characteristics. Lignocellulose-biomass (LCB) is a renewable source of carbon for the de... Read More about Bioprospecting novel hemicellulases from the gut microbiota of the common black slug (Arion ater).

Characterisation of a Novel Acetyl Xylan Esterase (BaAXE) screened from the Gut Microbiota of the Common Black Slug (Arion ater) (2022)
Journal Article
Madubuike, H., & Ferry, N. (2022). Characterisation of a Novel Acetyl Xylan Esterase (BaAXE) screened from the Gut Microbiota of the Common Black Slug (Arion ater). Molecules, 27(9), 2999. https://doi.org/10.3390/molecules27092999

Acetyl xylan esterases (AXEs) are enzymes capable of hydrolysing the acetyl bonds in acetylated xylan, allowing for enhanced activity of backbone-depolymerizing enzymes. Bioprospecting novel AXE is essential in designing enzyme cocktails with desired... Read More about Characterisation of a Novel Acetyl Xylan Esterase (BaAXE) screened from the Gut Microbiota of the Common Black Slug (Arion ater).

Fungal microbiomes are determined by host phylogeny and exhibit widespread associations with the bacterial microbiome (2021)
Journal Article
Harrison, X., McDevitt, A., Dunn, J., Grifftihs, S., Benvenuto, C., Birtles, R., …Antwis, R. (2021). Fungal microbiomes are determined by host phylogeny and exhibit widespread associations with the bacterial microbiome. Proceedings of the Royal Society B: Biological Sciences, 288(1957), 20210552. https://doi.org/10.1098/rspb.2021.0552

Interactions between hosts and their resident microbial communities are a fundamental component of fitness for both agents. Though recent research has highlighted the importance of interactions between animals and their bacterial communities, compara... Read More about Fungal microbiomes are determined by host phylogeny and exhibit widespread associations with the bacterial microbiome.

Characterization of sialic acid affinity of the binding domain of mistletoe lectin isoform one (2021)
Journal Article
Mohammed, S., & Ferry, N. (2021). Characterization of sialic acid affinity of the binding domain of mistletoe lectin isoform one. International Journal of Molecular Sciences, 22(15), e8284. https://doi.org/10.3390/ijms22158284

Sialic acid (Sia) is considered as one of the most important biomolecules of life since its derivatives and terminal orientations on cell membranes and macromolecules play a major role in many biological and pathological processes. To date, there is... Read More about Characterization of sialic acid affinity of the binding domain of mistletoe lectin isoform one.

Fungal microbiomes are determined by host phylogeny and exhibit widespread associations with the bacterial microbiome (2021)
Other
Harrison, X., McDevitt, A., Dunn, J., Griffiths, S., Benvenuto, C., Birtles, R., …Antwis, R. (2021). Fungal microbiomes are determined by host phylogeny and exhibit widespread associations with the bacterial microbiome

Interactions between hosts and their resident microbial communities are a fundamental component of fitness for both agents. Though recent research has highlighted the importance of interactions between animals and their bacterial communities, compara... Read More about Fungal microbiomes are determined by host phylogeny and exhibit widespread associations with the bacterial microbiome.

Circular and linear : a tale of aptamer selection for the activation of SIRT1 to induce death in cancer cells (2020)
Journal Article
Al-Sudani, B., Ragazzon-Smith, A., Aziz, A., Alansari, R., Ferry, N., Krstic- Demonacos, M., & Ragazzon, P. (2020). Circular and linear : a tale of aptamer selection for the activation of SIRT1 to induce death in cancer cells. RSC Advances, 10(73), 45008-45018. https://doi.org/10.1039/D0RA07857C

It is a challenge to select the right target to treat conditions without affecting non-diseased cells. Cancer belongs to the top 10 causes of death in the world and it remains difficult to treat. Amongst cancer emerging targets, silent information re... Read More about Circular and linear : a tale of aptamer selection for the activation of SIRT1 to induce death in cancer cells.

Metagenomic analysis of the gut microbiome of the common black slug Arion ater in search of novel lignocellulose degrading enzymes (2017)
Journal Article
Joynson, R., Pritchard, L., Ekenakema, O., & Ferry, N. (2017). Metagenomic analysis of the gut microbiome of the common black slug Arion ater in search of novel lignocellulose degrading enzymes. Frontiers in Microbiology, 8, 2181. https://doi.org/10.3389/fmicb.2017.02181

Some eukaryotes are able to gain access to well-protected carbon sources in plant biomass by exploiting microorganisms in the environment or harbored in their digestive system. One is the land pulmonate Arion ater, which takes advantage of a gut micr... Read More about Metagenomic analysis of the gut microbiome of the common black slug Arion ater in search of novel lignocellulose degrading enzymes.

Proteomic analysis shows that stress response proteins are significantly up-regulated in resistant diploid wheat (Triticum monococcum) in response to attack by the grain aphid (Sitobion avenae) (2015)
Journal Article
Guan, W., Ferry, N., Edwards, M., Bell, H., Othman, H., Gatehouse, J., & Gatehouse, A. (2015). Proteomic analysis shows that stress response proteins are significantly up-regulated in resistant diploid wheat (Triticum monococcum) in response to attack by the grain aphid (Sitobion avenae). Molecular Breeding, 35(2), https://doi.org/10.1007/s11032-015-0220-x

The grain aphid Sitobion avenae (F.) is a major pest of wheat, acting as a virus vector as well as causing direct plant damage. Commonly grown wheat varieties in the UK have only limited resistance to this pest. The present study was carried out to i... Read More about Proteomic analysis shows that stress response proteins are significantly up-regulated in resistant diploid wheat (Triticum monococcum) in response to attack by the grain aphid (Sitobion avenae).

Characterization of cellulolytic activity in the gut of the terrestrial land slug Arion ater : Biochemical identification of targets for intensive study (2014)
Journal Article
Joynson, R., Swamy, A., Bou, P., Chapuis, A., & Ferry, N. (2014). Characterization of cellulolytic activity in the gut of the terrestrial land slug Arion ater : Biochemical identification of targets for intensive study. Comparative Biochemistry and Physiology - Part B: Biochemistry and Molecular Biology, 177, 29-35. https://doi.org/10.1016/j.cbpb.2014.08.003

The level of cellulolytic activity in different areas of the gut of the terrestrial slug Arion ater was assayed at different temperatures and pH values. To do this, crude gut proteins were isolated and assayed using modified dinitrosalicylic acid red... Read More about Characterization of cellulolytic activity in the gut of the terrestrial land slug Arion ater : Biochemical identification of targets for intensive study.

Characterization of four midgut aminopeptidase N isozymes from Ostrinia furnacalis strains with different susceptibilities to Bacillus thuringiensis (2013)
Journal Article
Xu, L., Wang, Z., Zhang, J., Ferry, N., Edwards, M., Gatehouse, A., & He, K. (2014). Characterization of four midgut aminopeptidase N isozymes from Ostrinia furnacalis strains with different susceptibilities to Bacillus thuringiensis. Journal of Invertebrate Pathology, 115, 95-98. https://doi.org/10.1016/j.jip.2013.11.001

The full-length cDNA of four Ofapn aminopeptidases were cloned and sequenced from susceptible and resistant Ostrinia furnacalis strains. Four sequences were identified as APN because they shared the common structural features with APN from Lepidopter... Read More about Characterization of four midgut aminopeptidase N isozymes from Ostrinia furnacalis strains with different susceptibilities to Bacillus thuringiensis.

A proteomic approach to study the mechanism of tolerance to Bt toxins in Ostrinia furnacalis larvae selected for resistance to Cry1Ab (2013)
Journal Article
Xu, L., Ferry, N., Wang, Z., Zhang, J., Edwards, M. G., Gatehouse, A. M., & He, K. A proteomic approach to study the mechanism of tolerance to Bt toxins in Ostrinia furnacalis larvae selected for resistance to Cry1Ab. Transgenic Research, 22, 1155–1166. https://doi.org/10.1007/s11248-013-9718-3

A Cry1Ab-resistant population of Asian corn borer (ACB-AbR) exhibiting approximately 100 times greater resistance to activated Cry1Ab than a susceptible population (Ostrinia furnacalis; ACB-BtS), was previously shown to exhibit high levels of cross-r... Read More about A proteomic approach to study the mechanism of tolerance to Bt toxins in Ostrinia furnacalis larvae selected for resistance to Cry1Ab.

Successes and failures in plant-insect interactions: Is it possible to stay one step ahead of the insects? (2012)
Book Chapter
Gatehouse, A., & Ferry, N. (2012). Successes and failures in plant-insect interactions: Is it possible to stay one step ahead of the insects?. . Springer. https://doi.org/10.1007/978-94-007-3873-7_4

Home Arthropod-Plant Interactions Chapter Successes and Failures in Plant-Insect Interactions: Is it Possible to Stay One Step Ahead of the Insects? Angharad Gatehouse & Natalie Ferry Chapter First Online: 01 January 2012 1567 Accesses Par... Read More about Successes and failures in plant-insect interactions: Is it possible to stay one step ahead of the insects?.

Molecular interactions between wheat and the insect herbivore sitobion avenae (cereal aphid); analysis of changes to the wheat proteome (2011)
Journal Article
Ferry, N., Stavroulakis, S., Guan, W., Davison, G., Bell, H., Weaver, R., …Gatehouse, A. (2011). Molecular interactions between wheat and the insect herbivore sitobion avenae (cereal aphid); analysis of changes to the wheat proteome. Proteomics, 11(10), 1985-2002. https://doi.org/10.1002/pmic.200900801

Aphids are major insect pests of cereal crops, acting as virus vectors as well as causing direct damage. The responses of wheat to infestation by cereal aphid (Sitobion avenae) were investigated in a proteomic analysis. Approximately, 500 protein spo... Read More about Molecular interactions between wheat and the insect herbivore sitobion avenae (cereal aphid); analysis of changes to the wheat proteome.

Insect-resistant biotech crops and their impacts on beneficial arthropods (2011)
Journal Article
Gatehouse, A., Ferry, N., Edwards, M., & Bell, H. (2011). Insect-resistant biotech crops and their impacts on beneficial arthropods. Philosophical Transactions B: Biological Sciences, 366(1569), 1438-52. https://doi.org/10.1098/rstb.2010.0330

With a projected population of 10 billion by 2050, an immediate priority for agriculture is to achieve increased crop yields in a sustainable and cost-effective way. The concept of using a transgenic approach was realized in the mid-1990s with the co... Read More about Insect-resistant biotech crops and their impacts on beneficial arthropods.

Cross-resistance of Cry1Ab-selected Asian corn borer to other Cry toxins (2010)
Journal Article
Xu, L., Wang, Z., Zhang, J., Ferry, N., & Gatehouse, A. (2010). Cross-resistance of Cry1Ab-selected Asian corn borer to other Cry toxins. Journal of Applied Entomology, 134(5), 429-438. https://doi.org/10.1111/j.1439-0418.2010.01517.x

The Asian corn borer, Ostrinia furnacalis (Guene´e) (Lepidoptera: Crambidae), is the most important insect pest of maize in China. Despite the proven track record of biotech Bacillus thuringiensis (Bt) maize to provide an effective means to control l... Read More about Cross-resistance of Cry1Ab-selected Asian corn borer to other Cry toxins.

Characterisation of adult green lacewing (Chrysoperla carnea) digestive physiology: impact of a cysteine protease inhibitor and a synthetic pyrethroid (2010)
Journal Article
Mulligan, E., Ferry, N., Jouanin, L., Romeis, J., & Gatehouse, A. (2010). Characterisation of adult green lacewing (Chrysoperla carnea) digestive physiology: impact of a cysteine protease inhibitor and a synthetic pyrethroid. Pest Management Science, 66(3), 325-36. https://doi.org/10.1002/ps.1879

This study demonstrates the potential for pest management to impact on predators, but importantly it highlights the ability of the predator to detoxify/respond to treatments with different modes of action. In this case, exposure to an insecticide car... Read More about Characterisation of adult green lacewing (Chrysoperla carnea) digestive physiology: impact of a cysteine protease inhibitor and a synthetic pyrethroid.

Impact of transgenic oilseed rape expressing oryzacystatin-1 (OC-1) and of insecticidal proteins on longevity and digestive enzymes of the solitary bee Osmia bicornis. (2009)
Journal Article
Konrad, R., Connor, M., Ferry, N., Gatehouse, A., & Babendreier, D. (2009). Impact of transgenic oilseed rape expressing oryzacystatin-1 (OC-1) and of insecticidal proteins on longevity and digestive enzymes of the solitary bee Osmia bicornis. Journal of Insect Physiology, 55(4), 305-13. https://doi.org/10.1016/j.jinsphys.2008.12.007

The risk that insect-resistant transgenic plants may pose for solitary bees was assessed by determining longevity of adult Osmia bicornis (O. rufa) chronically exposed to transgenic oilseed rape expressing oryzacystatin-1 (OC-1) or to the purified in... Read More about Impact of transgenic oilseed rape expressing oryzacystatin-1 (OC-1) and of insecticidal proteins on longevity and digestive enzymes of the solitary bee Osmia bicornis..

Appropriate analytical methods are necessary to assess nontarget effects of insecticidal proteins in GM crops through meta-analysis (response to Andow et al. 2009) (2009)
Journal Article
Shelton, A., Naranjo, S., Romeis, J., Hellmich, R., Wolt, J., Federici, B., …Bell, H. (2009). Appropriate analytical methods are necessary to assess nontarget effects of insecticidal proteins in GM crops through meta-analysis (response to Andow et al. 2009). Environmental Entomology, 38(6), 1533-1536

As we described in our rebuttal in Transgenic Research (Shelton et al. 2009), we think that the meta-analysis approach used by Lo¨ vei et al. (2009) suffers from important methodological limitations relative to risk assessment that led them to re... Read More about Appropriate analytical methods are necessary to assess nontarget effects of insecticidal proteins in GM crops through meta-analysis (response to Andow et al. 2009).

Agriculture, innovation and environment (2009)
Book Chapter
Ferry, N., & Gatehouse, A. (2009). Agriculture, innovation and environment. In N. Ferry, & A. Gatehouse (Eds.), Environmental Impact of Genetically Modified Crops. CABI

Approximately 10.3 million farmers in 22 countries grew biotech (genetically modified) crops in 2006. Yet this technology remains one of the most controversial agricultural issues of current times. Many consumer and environmental lobby groups believe... Read More about Agriculture, innovation and environment.

Characterisation of midgut digestive proteases from the maize stem borer Busseola fusca (2008)
Journal Article
George, D., Ferry, N., Back, E., & Gatehouse, A. (2008). Characterisation of midgut digestive proteases from the maize stem borer Busseola fusca. Pest Management Science, 64(11), 1151-1158. https://doi.org/10.1002/ps.1610

BACKGROUND: Insect damage is a major constraint on maize production. Control of Busseola fusca (Fuller) in sub-Saharan Africa is relatively ineffective; the major larval digestive enzymes were characterised with a view to developing future control... Read More about Characterisation of midgut digestive proteases from the maize stem borer Busseola fusca.

Prey mediated effects of Bt maize on fitness and digestive physiology of the red spider mite predator Stethorus punctillum Weise (Coleoptera: Coccinellidae). (2008)
Journal Article
Alvarez-Alfageme, F., Ferry, N., Castañera, P., Ortego, F., & Gatehouse, A. (2008). Prey mediated effects of Bt maize on fitness and digestive physiology of the red spider mite predator Stethorus punctillum Weise (Coleoptera: Coccinellidae). Transgenic Research, 17(5), 943-54. https://doi.org/10.1007/s11248-008-9177-4

The present study investigated prey-mediated effects of two maize varieties expressing a truncated Cry1Ab, Compa CB (event Bt176) and DKC7565 (event MON810), on the biology of the ladybird Stethorus punctillum. Although immuno-assays demonstrated the... Read More about Prey mediated effects of Bt maize on fitness and digestive physiology of the red spider mite predator Stethorus punctillum Weise (Coleoptera: Coccinellidae)..

Potential effects of oilseed rape expressing oryzacystatin-1 (OC-1) and of purified insecticidal proteins on larvae of the solitary bee Osmia bicornis (2008)
Journal Article
Konrad, R., Ferry, N., Gatehouse, A., & Babendreier, D. (2008). Potential effects of oilseed rape expressing oryzacystatin-1 (OC-1) and of purified insecticidal proteins on larvae of the solitary bee Osmia bicornis. PLoS ONE, 3(7), e2664. https://doi.org/10.1371/journal.pone.0002664

Despite their importance as pollinators in crops and wild plants, solitary bees have not previously been included in non-target testing of insect-resistant transgenic crop plants. Larvae of many solitary bees feed almost exclusively on pollen and thu... Read More about Potential effects of oilseed rape expressing oryzacystatin-1 (OC-1) and of purified insecticidal proteins on larvae of the solitary bee Osmia bicornis.

Bitrophic and tritrophic effects of Bt Cry3A transgenic potato on beneficial, non-target, beetles. (2007)
Journal Article
Ferry, N., Mulligan, E., Majerus, M., & Gatehouse, A. (2007). Bitrophic and tritrophic effects of Bt Cry3A transgenic potato on beneficial, non-target, beetles. Transgenic Research, 16(6), 795-812. https://doi.org/10.1007/s11248-007-9088-9

Insect-resistant transgenic plants have been suggested to have unpredictable effects on the biodiversity of the agro-ecosystem, including potential effects on insect natural enemies, beneficial in control of crop pests. Whilst carnivorous as adults,... Read More about Bitrophic and tritrophic effects of Bt Cry3A transgenic potato on beneficial, non-target, beetles..

Prey-mediated effects of transgenic canola on a beneficial, non-target, carabid beetle. (2006)
Journal Article
Ferry, N., Mulligan, E., Stewart, C., Tabashnik, B., Port, G., & Gatehouse, A. (2006). Prey-mediated effects of transgenic canola on a beneficial, non-target, carabid beetle. Transgenic Research, 15(4), 501-14. https://doi.org/10.1007/s11248-006-0021-4

Transgenic plants producing insecticidal proteins from Bacillus thuringiensis (Bt) can control some major insect pests and reduce reliance on sprayed insecticides. However, large scale adoption of this technology has raised concerns about potential n... Read More about Prey-mediated effects of transgenic canola on a beneficial, non-target, carabid beetle..

Transgenic plants for insect pest control: a forward looking scientific perspective (2006)
Journal Article
Ferry, N., Edwards, M., Gatehouse, J., Capell, T., Christou, P., & Gatehouse, A. (2006). Transgenic plants for insect pest control: a forward looking scientific perspective. Transgenic Research, 15(1), 13-9. https://doi.org/10.1007/s11248-005-4803-x

One of the first successes of plant biotechnology has been the creation and commercialisation of transgenic crops exhibiting resistance to major insect pests. First generation products encompassed plants with single insecticidal Bt genes with resista... Read More about Transgenic plants for insect pest control: a forward looking scientific perspective.

Comparing the impact of conventional pesticide and use of a transgenic pest-resistant crop on the beneficial carabid beetle Pterostichus melanarius (2006)
Journal Article
Mulligan, E., Ferry, N., Jouanin, L., Walters, K., Port, G., & Gatehouse, A. (2006). Comparing the impact of conventional pesticide and use of a transgenic pest-resistant crop on the beneficial carabid beetle Pterostichus melanarius. Pest Management Science, 62(10), 999-1012. https://doi.org/10.1002/ps.1276

The potential impact of a chemical pesticide control method has been compared with that of transgenic plants expressing a protease inhibitor conferring insect resistance by utilising a tritrophic system comprising the crop plant Brassica napus (L.) (... Read More about Comparing the impact of conventional pesticide and use of a transgenic pest-resistant crop on the beneficial carabid beetle Pterostichus melanarius.

Direct effects of snowdrop lectin (GNA) on larvae of three aphid predators and fate of GNA after ingestion (2006)
Journal Article
Hogervorst, P., Ferry, N., Gatehouse, A., Wäckers, F., & Romeis, J. (2006). Direct effects of snowdrop lectin (GNA) on larvae of three aphid predators and fate of GNA after ingestion. Journal of Insect Physiology, 52(6), 614-24. https://doi.org/10.1016/j.jinsphys.2006.02.011

Plants genetically modified to express Galanthus nivalis agglutinin (GNA) have been found to confer partial resistance to homopteran pests. Laboratory experiments were conducted to investigate direct effects of GNA on larvae of three species of aphid... Read More about Direct effects of snowdrop lectin (GNA) on larvae of three aphid predators and fate of GNA after ingestion.

How family 26 glycoside hydrolases orchestrate catalysis on different polysaccharides: Structure and activity of a Clostridium thermocellum lichenase, CtLic26A (2005)
Journal Article
Taylor, E. J., Goyal, A., Guerreiro, C. I., Prates, J. A., Money, V. A., Ferry, N., …Davies, G. J. (2005). How family 26 glycoside hydrolases orchestrate catalysis on different polysaccharides: Structure and activity of a Clostridium thermocellum lichenase, CtLic26A. Journal of biological chemistry, 280(38), https://doi.org/10.1074/jbc.M506580200

One of the most intriguing features of the 90 glycoside hydrolase families (GHs) is the range of specificities displayed by different members of the same family, whereas the catalytic apparatus and mechanism are often invariant. Family GH26 predomina... Read More about How family 26 glycoside hydrolases orchestrate catalysis on different polysaccharides: Structure and activity of a Clostridium thermocellum lichenase, CtLic26A.

Impact of oilseed rape expressing the insecticidal serine protease inhibitor, mustard trypsin inhibitor-2 on the beneficial predator Pterostichus madidus (2004)
Journal Article
Ferry, N., Jouanin, L., Ceci, L., Mulligan, E., Emami, K., Gatehouse, J., & Gatehouse, A. (2005). Impact of oilseed rape expressing the insecticidal serine protease inhibitor, mustard trypsin inhibitor-2 on the beneficial predator Pterostichus madidus. Molecular Ecology, 14(1), 337-349. https://doi.org/10.1111/j.1365-294X.2004.02381.x

Insect-resistant transgenic plants have been suggested to have deleterious effects on beneficial predators feeding on crop pests, through transmission of the transgene product by the pest to the predator. To test this hypothesis, effects of oilseed r... Read More about Impact of oilseed rape expressing the insecticidal serine protease inhibitor, mustard trypsin inhibitor-2 on the beneficial predator Pterostichus madidus.

Plant-insect interactions: Molecular approaches to insect resistance (2004)
Journal Article
Ferry, N., Edwards, M. G., Gatehouse, J. A., & MR Gatehouse, A. (2004). Plant-insect interactions: Molecular approaches to insect resistance. Current Opinion in Biotechnology, 15(2), 155-161. https://doi.org/10.1016/j.copbio.2004.01.008

Recent advances in our understanding of induced responses in plants and their regulation, brought about by a revolution in molecular biology, have re-focused attention on the potential exploitation of endogenous resistance mechanisms for crop protect... Read More about Plant-insect interactions: Molecular approaches to insect resistance.

Impact of oilseed rape expressing the insecticidal cysteine protease inhibitor oryzacystatin on the beneficial predator Harmonia axyridis (multicoloured Asian ladybeetle) (2003)
Journal Article
Ferry, N., Raemaekers, R., Majerus, M., Jouanin, L., Port, G., Gatehouse, J., & Gatehouse, A. (2003). Impact of oilseed rape expressing the insecticidal cysteine protease inhibitor oryzacystatin on the beneficial predator Harmonia axyridis (multicoloured Asian ladybeetle). Molecular Ecology, 12(2), 493-504. https://doi.org/10.1046/j.1365-294X.2003.01736.x

Insect-resistant transgenic plants have been suggested to have deleterious effects on beneficial predators through transmission of the transgene product by the pest to the predator. To test this hypothesis, effects of oilseed rape expressing the cyst... Read More about Impact of oilseed rape expressing the insecticidal cysteine protease inhibitor oryzacystatin on the beneficial predator Harmonia axyridis (multicoloured Asian ladybeetle).

The case of the monarch butterfly: A verdict is returned (2002)
Journal Article
Gatehouse, A., Ferry, N., & Raemaekers, R. (2002). The case of the monarch butterfly: A verdict is returned. Trends in Genetics, 18(5), 249-251. https://doi.org/10.1016/S0168-9525%2802%2902664-1

A publication reporting the harmful effects on the monarch butterfly of maize genetically modified to express insecticidal δ-endotoxins from the soil bacterium Bacillus thuringiensis (Bt) caused much public interest. A series of ecologically based st... Read More about The case of the monarch butterfly: A verdict is returned.

Biochemical characteristics and antimicrobial potential of seed and nut oils against Staphylococcus aureus
Thesis
Yangomodou, O. (in press). Biochemical characteristics and antimicrobial potential of seed and nut oils against Staphylococcus aureus. (Thesis). University of Salford

The antibacterial activities of oils and extracts from walnut, cashew and pumpkin were investigated on methicillin resistant and susceptible strain MRSA 252 and S. aureus ATCC 6538 using the disc agar diffusion technique. Results revealed that the te... Read More about Biochemical characteristics and antimicrobial potential of seed and nut oils against Staphylococcus aureus.

Expression and characterization of recombinant human NEIL3 from Escherichia coli
Thesis
Albelazi, M. (in press). Expression and characterization of recombinant human NEIL3 from Escherichia coli. (Thesis). University of Salford

The DNA glycosylase NEIL3 is one of a family of proteins that release oxidized bases from DNA, thereby initiating base excision repair. NEIL3 gene expression is normally tightly regulated and expressed only in certain rapidly dividing cells, however,... Read More about Expression and characterization of recombinant human NEIL3 from Escherichia coli.

Novel fusion proteins based on recombinant lectins for delivery of a cytotoxic peptide specifically to cancer cells
Thesis
Mohammed, S. Novel fusion proteins based on recombinant lectins for delivery of a cytotoxic peptide specifically to cancer cells. (Thesis). University of Salford

One of the most common post-translational modifications is covalent attachment of carbohydrates to proteins. At the cell surface, molecular recognition events involved in cancer metastasis are mediated by sugar moieties of glycoproteins. Evidence fro... Read More about Novel fusion proteins based on recombinant lectins for delivery of a cytotoxic peptide specifically to cancer cells.

Analysis of the gut microbiome of the common black slug Arion ater : in search of novel lignocellulose degrading enzymes
Thesis
Joynson, R. (in press). Analysis of the gut microbiome of the common black slug Arion ater : in search of novel lignocellulose degrading enzymes. (Thesis). University of Salford

Some eukaryotes are able to gain access to otherwise well-protected carbon sources in plant biomass by exploiting microorganisms in the environment, or harboured in their digestive system. One such organism is the European black slug, Arion ater, whi... Read More about Analysis of the gut microbiome of the common black slug Arion ater : in search of novel lignocellulose degrading enzymes.