Dr Mark McAuley's Outputs (4)

Computationally Modeling Lipid Metabolism and Aging: A Mini-review (2015)
Journal Article

One of the greatest challenges in biology is to improve the understanding of the mechanisms which underpin aging and how these affect health. The need to better understand aging is amplified by demographic changes, which have caused a gradual increas... Read More about Computationally Modeling Lipid Metabolism and Aging: A Mini-review.

Cardiovascular disease and healthy ageing (2015)
Journal Article

Cardiovascular diseases are main cause of morbidity and mortality in the Western World. Cardiovascular disease increases in its prevalence with age and the burden of this condition is set to increase with an Ageing global population. There are many f... Read More about Cardiovascular disease and healthy ageing.

Mathematical Modelling of Metabolic Regulation in Aging (2015)
Journal Article

The underlying cellular mechanisms that characterize aging are complex and multifaceted. However, it is emerging that aging could be regulated by two distinct metabolic hubs. These hubs are the pathway defined by the mammalian target of rapamycin (mT... Read More about Mathematical Modelling of Metabolic Regulation in Aging.

Systems Biology and Synthetic Biology: A New Epoch for Toxicology Research (2015)
Journal Article

Systems biology and synthetic biology are emerging disciplines which are becoming increasingly utilised in several areas of bioscience. Toxicology is beginning to benefit from systems biology and we suggest in the future that is will also benefit fro... Read More about Systems Biology and Synthetic Biology: A New Epoch for Toxicology Research.