Prof Joseph Jackson J.A.Jackson@salford.ac.uk
Professor
Immunodynamics and infectious disease risk in the natural environment
People Involved
Early‐life immune expression profiles predict later‐life health and fitness in a wild rodent (2023)
Journal Article
Wanelik, K. M., Begon, M., Bradley, J. E., Friberg, I. M., Taylor, C. H., Jackson, J. A., & Paterson, S. (2023). Early‐life immune expression profiles predict later‐life health and fitness in a wild rodent. Molecular Ecology, 32(13), 3471-3482. https://doi.org/10.1111/mec.16950Individuals differ in the nature of the immune responses they produce, affecting dis-ease susceptibility and ultimately health and fitness. These differences have been hypothesized to have an origin in events experienced early in... Read More about Early‐life immune expression profiles predict later‐life health and fitness in a wild rodent.
Discrete patterns of microbiome variability across timescales in a wild rodent population (2023)
Journal Article
Mammalian gastrointestinal microbiomes are highly variable, both within individuals and across populations, with
changes linked to time and ageing being widely reported. Discerning patterns of change in wild mammal popula-
tions can therefore prove... Read More about Discrete patterns of microbiome variability across timescales in a wild rodent population.
Physiological, but not fitness, effects of two interacting haemoparasitic infections in a wild rodent (2018)
Journal Article
In contrast to the conditions in most laboratory studies, wild animals are routinely challenged by multiple infections at once, and these infections can interact in complex ways. This means that the impact of a parasite on its host’s physiology and f... Read More about Physiological, but not fitness, effects of two interacting haemoparasitic infections in a wild rodent.
A candidate tolerance gene identified in a natural population of field voles (Microtus agrestis) (2017)
Journal Article
The animal immune response has hitherto been viewed primarily in the context of resistance only. However, individuals, can also employ a tolerance strategy to maintain good health in the face of on-going infection. To shed light on the genetic and ph... Read More about A candidate tolerance gene identified in a natural population of field voles (Microtus agrestis).
An endemic hantavirus in field voles in northern England (2017)
Journal Article
Thomason, A., Begon, M., Bradley, J., Paterson, S., & Jackson, J. (2017). An endemic hantavirus in field voles in northern England. Emerging Infectious Diseases, 23(6), https://doi.org/10.3201/eid2306.161607We report a PCR survey of hantavirus infection in the extensive field vole (Microtus agrestis) populations occurring in the Kielder Forest, northern England. A Tatenale virus-like lineage was frequently detected (~ 15% prevalence) in liver tissue. Su... Read More about An endemic hantavirus in field voles in northern England.
Immunology in wild nonmodel rodents : an ecological context for studies of health and disease (2015)
Journal Article
Jackson, J. (2015). Immunology in wild nonmodel rodents : an ecological context for studies of health and disease. Parasite Immunology, 37(5), 220-232. https://doi.org/10.1111/pim.12180Transcriptomic methods are set to revolutionize the study of
the immune system in naturally occurring nonmodel organisms.
With this in mind, the present article focuses on ways in which the use of ‘nonmodel’ rodents (not the familiar laboratory spe... Read More about Immunology in wild nonmodel rodents : an ecological context for studies of health and disease.