Mechanistic studies on aziridinylbenzoquinones and CCNU [l-(2-chloroethyl)- 3-cyclohexyl-l-nitrosourea] in cultured tumour cells
(2007)
Thesis
Ben Raba, F. Mechanistic studies on aziridinylbenzoquinones and CCNU [l-(2-chloroethyl)- 3-cyclohexyl-l-nitrosourea] in cultured tumour cells. (Thesis). University of Salford
This work is concerned with the action of two different anticancer drugs which can
alkylate DNA in tumour cells.
The first alkylating agent studied was CCNU [(l-(2-chloroethyl)-3-cyclohexyl-lnitrosourea,
Lomustine]. This is a well established clin...
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