Outputs (15087)

Long non-coding RNAs and their potential impact on diagnosis, prognosis, and therapy in prostate cancer: Racial, ethnic, and geographical considerations (2021)
Journal Article
Morgan, R., Abraham da Silveira, W., Christopher Kelly, R., Overton, I., Allott, E. H., & Hardiman, G. (2021). Long non-coding RNAs and their potential impact on diagnosis, prognosis, and therapy in prostate cancer: Racial, ethnic, and geographical considerations. Expert Review of Molecular Diagnostics, 21(12), 1257-1271. https://doi.org/10.1080/14737159.2021.1996227

Introduction: Advances in high-throughput sequencing have greatly advanced our understanding of long non-coding RNAs (lncRNAs) in a relatively short period of time. This has expanded our knowledge of cancer, particularly how lncRNAs drive many import... Read More about Long non-coding RNAs and their potential impact on diagnosis, prognosis, and therapy in prostate cancer: Racial, ethnic, and geographical considerations.

Wild Meat Is Still on the Menu: Progress in Wild Meat Research, Policy, and Practice from 2002 to 2020 (2021)
Journal Article

Several hundred species are hunted for wild meat in the tropics, supporting the diets, customs, and livelihoods of millions of people. However, unsustainable hunting is one of the most urgent threats to wildlife and ecosystems worldwide and has serio... Read More about Wild Meat Is Still on the Menu: Progress in Wild Meat Research, Policy, and Practice from 2002 to 2020.

Temperature and exudativory as drivers of the marmoset (Callithrix spp.) daily activity period (2021)
Journal Article

Primates are affected by fluctuations in ambient temperatures, mostly through thermoregulatory costs and changes in the availability of food. In the present study, we investigate whether the ambient temperature and proxies of food availability affect... Read More about Temperature and exudativory as drivers of the marmoset (Callithrix spp.) daily activity period.

A hierarchical Bayesian-based model for hazard analysis of climate effect on failures of railway turnout components (2021)
Journal Article

There has been a considerable increase in derailment investigations, in particular at railway turnouts (RTs), as the majority of derailments lead to lengthy disruptions to the appropriate rail operation and catastrophic consequences, being potentiall... Read More about A hierarchical Bayesian-based model for hazard analysis of climate effect on failures of railway turnout components.

High ATP production fuels cancer drug resistance and metastasis : implications for mitochondrial ATP depletion therapy (2021)
Journal Article
Fiorillo, M., Ozsvari, B., Sotgia, F., & Lisanti, M. (2021). High ATP production fuels cancer drug resistance and metastasis : implications for mitochondrial ATP depletion therapy. Frontiers in Oncology, 11, 740720. https://doi.org/10.3389/fonc.2021.740720

Recently, we presented evidence that high mitochondrial ATP production is a new therapeutic target for cancer treatment. Using ATP as a biomarker, we isolated the “metabolically fittest” cancer cells from the total cell population. Importantly, ATP-h... Read More about High ATP production fuels cancer drug resistance and metastasis : implications for mitochondrial ATP depletion therapy.

High resistance to Toxoplasma gondii infection in inducible nitric oxide synthase (iNOS) knockout rats (2021)
Journal Article

Nitric oxide (NO) is an important immune molecule which acts against extra- and intracellular pathogens in most hosts. However, after knockout of inducible nitric oxide synthase (iNOS-/-) in Sprague Dawley (SD) rats, these iNOS-/- rats were found to... Read More about High resistance to Toxoplasma gondii infection in inducible nitric oxide synthase (iNOS) knockout rats.

DNA methylation in genes associated with the evolution of ageing and disease: A critical review (2021)
Journal Article

Ageing is characterised by a physical decline in biological functioning which results in a progressive risk of mortality with time. As a biological phenomenon, it is underpinned by the dysregulation of a myriad of complex processes. Recently, however... Read More about DNA methylation in genes associated with the evolution of ageing and disease: A critical review.

Diurnal oscillations in gut bacterial load and composition eclipse seasonal and lifetime dynamics in wild meerkats (2021)
Journal Article
Risely, A., Wilhelm, K., Clutton-Brock, T., Manser, M. B., & Sommer, S. (2021). Diurnal oscillations in gut bacterial load and composition eclipse seasonal and lifetime dynamics in wild meerkats. Nature Communications, 12, https://doi.org/10.1038/s41467-021-26298-5

Circadian rhythms in gut microbiota composition are crucial for metabolic function, yet the extent to which they govern microbial dynamics compared to seasonal and lifetime processes remains unknown. Here, we investigate gut bacterial dynamics in wil... Read More about Diurnal oscillations in gut bacterial load and composition eclipse seasonal and lifetime dynamics in wild meerkats.

Investigation of de-novo copy number variants in patients with Autism Spectrum Disorder in Vietnam (2021)
Thesis
Bui, H. Investigation of de-novo copy number variants in patients with Autism Spectrum Disorder in Vietnam. (Thesis). University of Salford

Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a prevalence of approximately 1% children worldwide. ASD is characterized by deficits in social communication and interaction and the presence of restricted interests and repetitive... Read More about Investigation of de-novo copy number variants in patients with Autism Spectrum Disorder in Vietnam.

Role of sulphates and chloride ions in improved oil recovery in a hybrid smart-low salinity flooding technique (2021)
Thesis

The growing demand for energy to cater for the growing world population has forced the exploitation and utilisation of existing hydrocarbon resources. Oil and gas are deemed the most conventional and common sources of energy, formed as a result of d... Read More about Role of sulphates and chloride ions in improved oil recovery in a hybrid smart-low salinity flooding technique.