Outputs (14827)

PWE-199 Metabolomic profiling in acute pancreatitis; in search of new biomarkers (2015)
Journal Article
Ross, N., Correa, E., Rattray, N., Hildebrand, D., Trivedi, D., Goodacre, R., & Watson, A. (2015). PWE-199 Metabolomic profiling in acute pancreatitis; in search of new biomarkers. Gut, 64(Suppl), A299.2-A300. https://doi.org/10.1136/gutjnl-2015-309861.646

Introduction Severe acute pancreatitis (AP) carries a 30–50% mortality.1Current scoring systems fall short in predictive accuracy, sensitivity, specificity and availability.2Metabolomics aims to decipher molecular signatures that will distinguish dis... Read More about PWE-199 Metabolomic profiling in acute pancreatitis; in search of new biomarkers.

PWE-200 Metabolomic profiling in pancreatic cancer; in search of new biomarkers (2015)
Journal Article

Introduction Pancreatic cancer is a devastating disease with a poor outcome. Current biomarkers fall short in accessibility, sensitivity, specificity and their ability to distinguish malignant from benign conditions. Metabolomics aims to decipher mol... Read More about PWE-200 Metabolomic profiling in pancreatic cancer; in search of new biomarkers.

PTU-093 Metabolomic profiling in inflammatory bowel disease (2015)
Journal Article

Introduction Inflammatory bowel disease is classified into 2 main types; Crohn’s disease (CD) and ulcerative colitis (UC). Differentiation can prove clinically challenging. Metabolomic profiling is an emerging science that is utilised for biomarker d... Read More about PTU-093 Metabolomic profiling in inflammatory bowel disease.

Multi-Turing instabilities & spontaneous patterns in discrete nonlinear systems : simplicity and complexity, cavities and counterpropagation (2015)
Presentation / Conference
Bostock, C., Christian, J., Leite, A., McDonald, G., & Huang, J. (2015, June). Multi-Turing instabilities & spontaneous patterns in discrete nonlinear systems : simplicity and complexity, cavities and counterpropagation. Presented at 12th International Conference on the Mathematical and Numerical Aspects of Wave Propagation, Karlsruhe, Germany

Alan Turing's profound insight into morphogenesis, published in 1952, has provided the cornerstone for understanding the origin of pattern and form in Nature. When the uniform states of a nonlinear reaction-diffusion system are sufficiently stressed,... Read More about Multi-Turing instabilities & spontaneous patterns in discrete nonlinear systems : simplicity and complexity, cavities and counterpropagation.

Diffraction of optical Weierstrass waves by simple apertures : circular symmetry and fractal dimension (2015)
Presentation / Conference
Christian, J., Woodroofe, E., & McDonald, G. (2015, June). Diffraction of optical Weierstrass waves by simple apertures : circular symmetry and fractal dimension. Presented at Conference on Lasers and Electro-optics Europe - European Quantum Electronics Conference 2015, Munich, Germany

Novel therapies for cancer treatment : designing high affinity and selectivity ligands against SIRT1 (2015)
Presentation / Conference
Al-Sudani, B., Krstic- Demonacos, M., & Ragazzon, P. (2015, June). Novel therapies for cancer treatment : designing high affinity and selectivity ligands against SIRT1. Poster presented at EuroMedLab Paris 2015, Paris, France

The word ‘sirtuin’ (SIR) stands for Silent Information Regulator. SIRT1 is the most studied mammalian sirtuin and predominantly localises to the nucleus. Many sirtuins targets are involved in cancer and in many types of cancers, SIRT1 is found to be... Read More about Novel therapies for cancer treatment : designing high affinity and selectivity ligands against SIRT1.

Evaluating the predictions of objective intelligibility metrics for modified and synthetic speech (2015)
Journal Article
Tang, Y., Cooke, M., & Valentini-Botinhao, C. (2015). Evaluating the predictions of objective intelligibility metrics for modified and synthetic speech. Computer Speech and Language, 35, 73-92. https://doi.org/10.1016/j.csl.2015.06.002

Several modification algorithms that alter natural or synthetic speech with the goal of improving intelligibility in noise have been proposed recently. A key requirement of many modification techniques is the ability to predict intelligibility, both... Read More about Evaluating the predictions of objective intelligibility metrics for modified and synthetic speech.

ABCG2 is a potential marker of tumor-initiating cells in breast cancer (2015)
Journal Article

The existence of tumor-initiating cells (TICs) within solid tumors has been hypothesized to explain tumor heterogeneity and resistance to cancer therapy. In breast cancer, the expression of CD44 and CD24 and the activity of aldehyde dehydrogenase 1 (... Read More about ABCG2 is a potential marker of tumor-initiating cells in breast cancer.

Experimental Validation of an Optimized Wing Geometry Using Small Wind Tunnel Testing (2015)
Presentation / Conference Contribution

Fiber guiding at the Dirac frequency beyond photonic bandgaps (2015)
Journal Article

Light trapping within waveguides is a key practice of modern optics, both scientifically and technologically. Photonic crystal fibers traditionally rely on total internal reflection (index-guiding fibers) or a photonic bandgap (photonic-bandgap fiber... Read More about Fiber guiding at the Dirac frequency beyond photonic bandgaps.