Preparation and characterization of au nanoparticles capped with mercaptocarboranyl clusters

M. Cioran, A; Teixidor, F; Krpetic, Ž; Brust, M; Viñas, C

Abstract

The preparation of 3–4 nm and 10 nm gold nanoparticles capped with neutral carborane-based mercaptocarboranes, via two different preparative routes, is reported. The resulting boron-enriched nanomaterials exhibit complete dispersibility in water, opening the way for the use of these monolayer protected clusters (MPCs) in medical applications, such as boron neutron capture therapy (BNCT). These newly prepared MPCs have been characterized by FTIR, 1H and 11B NMR spectroscopy, UV-visible, centrifugal particle sizing (CPS), and, in some cases, inductively coupled plasma atomic emission spectrometry (ICP-AES). Water dispersibility exhibited by these MPCs allowed the study of the cellular uptake by HeLa cells.

Citation

M. Cioran, A., Teixidor, F., Krpetic, Ž., Brust, M., & Viñas, C. (2014). Preparation and characterization of au nanoparticles capped with mercaptocarboranyl clusters. Dalton Transactions, 43(13), 5054-5061. https://doi.org/10.1039/C3DT52872C

• Journal Article Type: Article
• Acceptance Date: Nov 15, 2013
• Online Publication Date: Nov 15, 2013
• Publication Date: Nov 15, 2014
• Deposit Date: Oct 6, 2016
• Journal: Dalton Trans.
• Print ISSN: 1477-9226
• Publisher: Royal Society of Chemistry
• Volume: 43
• Issue: 13
• Pages: 5054-5061
• DOI: https://doi.org/10.1039/C3DT52872C
• Publisher URL: http://dx.doi.org/10.1039/C3DT52872C
• Related Public URLs: http://pubs.rsc.org/en/content/articlelanding/2013/dt/c3dt52872c/unauth#!divAbstract
• Additional Information: Funders : Generalitat de Catalunya;Ministero de Ciancia e Innovacion;MEC;European Community Seventh Framework Programme; Projects : BisNano;CONACYT; Grant Number: 2009/SGR/00279; Grant Number: CTQ2010-16237; Grant Number: AP2007-01723; Grant Number: NMP-2010-EU-MEXICO-263878; Grant Number: NMP-2010-EU-MEXICO-125141