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The United Kingdom Paediatric Critical Care Society Study Group: The 20-Year Journey Toward Pragmatic, Randomized Clinical Trials (2022)
Journal Article
Peters, M. J., Ramnarayan, P., Scholefield, B. R., Tume, L. N., & Tasker, R. C. (2022). The United Kingdom Paediatric Critical Care Society Study Group: The 20-Year Journey Toward Pragmatic, Randomized Clinical Trials. Pediatric Critical Care Medicine, 23(12), 1067-1075. https://doi.org/10.1097/pcc.0000000000003099

Over the past two decades, pediatric intensive care research networks have been formed across North America, Europe, Asia, and Australia/New Zealand. The U.K. Paediatric Critical Care Society Study Group (PCCS-SG) has over a 20-year tradition of fost... Read More about The United Kingdom Paediatric Critical Care Society Study Group: The 20-Year Journey Toward Pragmatic, Randomized Clinical Trials.

Ventilator weaning and extubation practices in critically ill children: an Australian and New Zealand survey of practice (2022)
Journal Article
Schults, J., Charles, K., Harnischfeger, J., Erikson, S., Burren, J., Waak, M., …Long, D. (2022). Ventilator weaning and extubation practices in critically ill children: an Australian and New Zealand survey of practice. Australian Critical Care, https://doi.org/10.1016/j.aucc.2022.06.004

We aimed to (i) describe current weaning and extubation practices in children (protocols to identify weaning candidates, spontaneous breathing trials, and other aspects of care such as sedation weaning) and (ii) understand responsibilities for ventil... Read More about Ventilator weaning and extubation practices in critically ill children: an Australian and New Zealand survey of practice.

Paediatric early warning systems: not a simple answer to a complex question. (2022)
Journal Article
Roland, D., Powell, C., Lloyd, A., Trubey, R., Tume, L., Sefton, G., …Allen, D. (2022). Paediatric early warning systems: not a simple answer to a complex question. Archives of Disease in Childhood, https://doi.org/10.1136/archdischild-2022-323951

Paediatric early warning systems (PEWS) to reduce in-hospital mortality have been a laudable endeavour. Evaluation of their impact has rarely examined the internal validity of the components of PEWS in achieving desired outcomes. We highlight the ass... Read More about Paediatric early warning systems: not a simple answer to a complex question..

Gastric point-of-care ultrasound in acutely and critically ill children (POCUS-ped): a scoping review (2022)
Journal Article
Valla, F., Tume, L., Jotterand Chaparro, C., Arnold, P., Alrayashi, W., Morice, C., …Bouvet, L. (2022). Gastric point-of-care ultrasound in acutely and critically ill children (POCUS-ped): a scoping review. Frontiers in Pediatrics, 10, 921863. https://doi.org/10.3389/fped.2022.921863

Point-of-care ultrasound (POCUS) use is increasing in pediatric clinical settings. However, gastric POCUS is rarely used, despite its potential value in optimizing the diagnosis and management in several clinical scenarios (i.e., assessing gastric em... Read More about Gastric point-of-care ultrasound in acutely and critically ill children (POCUS-ped): a scoping review.

Using the TIDieR checklist to describe the intervention of the Sedation and Weaning in Children (SANDWICH) trial (2022)
Journal Article
Tume, L., Blackwood, B., McAuley, D., Morris, K., Peters, M., Jordan, J., …McIlmurray, L. (2022). Using the TIDieR checklist to describe the intervention of the Sedation and Weaning in Children (SANDWICH) trial. Nursing in Critical Care, 1-8. https://doi.org/10.1111/nicc.12810

Aim: The aim of this paper is to describe our experience of the using the TIDieR checklist in reporting a recent trial of sedation and ventilation weaning in critically children (the SANDWICH trial) Methods: The Template for Intervention Descriptio... Read More about Using the TIDieR checklist to describe the intervention of the Sedation and Weaning in Children (SANDWICH) trial.

Incidence of refeeding syndrome in critically ill children with nutritional support. (2022)
Journal Article
Blanc, S., Vasileva, T., Tume, L., Baudin, F., Chessel Ford, C., Chaparro Jotterand, C., & Valla, F. (2022). Incidence of refeeding syndrome in critically ill children with nutritional support. Frontiers in Pediatrics, 10, 932290. https://doi.org/10.3389/fped.2022.932290

Early enteral nutrition is recommended for critically ill children, potentially exposing those who are undernourished to the risk of refeeding syndrome. However, data on its incidence is lacking, and the heterogeneity of diagnostic criteria and frequ... Read More about Incidence of refeeding syndrome in critically ill children with nutritional support..

Point of care gastric ultrasound confirms the inaccuracy of gastric residual volume measurement by aspiration in critically ill children: GastriPed study (2022)
Journal Article
Valla, F., Cercueil, E., Morice, C., Tume, L., & Bouvet, L. (2022). Point of care gastric ultrasound confirms the inaccuracy of gastric residual volume measurement by aspiration in critically ill children: GastriPed study. Frontiers in Pediatrics, https://doi.org/10.3389/fped.2022.903944

Introduction: No consensus exists on how to define enteral nutrition tolerance in critically ill children, and the relevance of gastric residual volume (GRV) is currently debated. The use of point-of-care ultrasound (POCUS) is increasing among pedi... Read More about Point of care gastric ultrasound confirms the inaccuracy of gastric residual volume measurement by aspiration in critically ill children: GastriPed study.

The physical effects of wearing personal protective equipment: a scoping review (2022)
Journal Article
scoping review. https://doi.org/10.3396/ijic.v18.22415

Background: The COVID-19 pandemic has required healthcare workers to wear personal protective equipment (PPE), and although there is increasing awareness of the physical effects of wearing PPE, the literature has yet to be synthesised around this top... Read More about The physical effects of wearing personal protective equipment: a scoping review.

Is bolus or continuous enteral feeding better in critically ill children: an evidence-based review (2022)
Journal Article
Littler, H., & Tume, L. (2022). Is bolus or continuous enteral feeding better in critically ill children: an evidence-based review. Nursing in Critical Care, 28(1), 36-39. https://doi.org/10.1111/nicc.12788

Inadequate nutrition can lead to increased morbidity and mortality for mechanically ventilated children in the paediatric intensive care unit (PICU). Enteral feeding can either be delivered by gravity bolus (intermittent) feeding or continuously via... Read More about Is bolus or continuous enteral feeding better in critically ill children: an evidence-based review.

Planned peri-extubation fasting in critically ill children: an international survey of practice (2022)
Journal Article
Nabialek, T., Tume, L., Cercueil, E., Morice, C., Bouvet, L., Baudin, F., & Valla, F. (2022). Planned peri-extubation fasting in critically ill children: an international survey of practice. Frontiers in Pediatrics, https://doi.org/10.3389/fped.2022.905058

Introduction: Cumulative energy/protein deficit is associated with impaired outcomes in pediatric intensive care Units (PICU). Enteral nutrition is the preferred mode, but its delivery may be compromised by periods of feeding interruptions around pro... Read More about Planned peri-extubation fasting in critically ill children: an international survey of practice.

Use of selective gut decontamination in critically ill children : protocol for the Paediatric Intensive Care and Infection Control (PICnIC) pilot study (2022)
Journal Article
Brown, A., Ferrando-Vivas, P., Popa, M., Milla de la Fuente, G., Tume, J., Cuthbertson, B., …Pathan, N. (2022). Use of selective gut decontamination in critically ill children : protocol for the Paediatric Intensive Care and Infection Control (PICnIC) pilot study. BMJ Open, 12(3), e061838. https://doi.org/10.1136/bmjopen-2022-061838

Introduction: Healthcare-associated infections (HCAI) are a major cause of morbidity and mortality in critically ill children. In critically ill adults, there are data that suggest the use of Selective Decontamination of the Digestive tract (SDD), a... Read More about Use of selective gut decontamination in critically ill children : protocol for the Paediatric Intensive Care and Infection Control (PICnIC) pilot study.

Research Priorities for Pediatric Intensive Care Nutrition Within the United Kingdom: A National Institute of Health Research James Lind Alliance Priority Setting Partnership (2022)
Journal Article
O'Connor, G., Marino, L. V., Tume, L. N., Stewart, A., Gates, S., Lanigan, J., …Kinsella, S. (2022). Research Priorities for Pediatric Intensive Care Nutrition Within the United Kingdom: A National Institute of Health Research James Lind Alliance Priority Setting Partnership. Critical Care Explorations, 4(3), e0649. https://doi.org/10.1097/cce.0000000000000649

OBJECTIVES: To determine research priorities in PICU nutrition, which represent the shared priorities of patients, parents, carers, and PICU healthcare professionals within the United Kingdom. DESIGN: A national multiphase priority setting methodolog... Read More about Research Priorities for Pediatric Intensive Care Nutrition Within the United Kingdom: A National Institute of Health Research James Lind Alliance Priority Setting Partnership.

Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation : the SANDWICH cluster stepped-wedge RCT (2022)
Journal Article
Blackwood, B., Morris, K., Jordan, J., McIlmurray, L., Agus, A., Boyle, R., …McAuley, D. (2022). Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation : the SANDWICH cluster stepped-wedge RCT. Health Technology Assessment, 26(18), 1-114. https://doi.org/10.3310/tcfx3817

Background Daily assessment of patient readiness for liberation from invasive mechanical ventilation can reduce the duration of ventilation. However, there is uncertainty about the effectiveness of this in a paediatric population. Objectives To deter... Read More about Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation : the SANDWICH cluster stepped-wedge RCT.

Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation: the SANDWICH cluster stepped-wedge RCT (2022)
Journal Article
SANDWICH cluster stepped-wedge RCT. Health Technology Assessment, 26(18), https://doi.org/10.3310/TCFX3817

Background: Daily assessment of patient readiness for liberation from invasive mechanical ventilation can reduce the duration of ventilation. However, there is uncertainty about the effectiveness of this in a paediatric population. Objectives:... Read More about Co-ordinated multidisciplinary intervention to reduce time to successful extubation for children on mechanical ventilation: the SANDWICH cluster stepped-wedge RCT.

Spotlight on cardiac intensive care nursing (Editorial) (2022)
Journal Article
Tume, L., & Trapani, J. (2022). Spotlight on cardiac intensive care nursing (Editorial). Nursing in Critical Care, 27(2), 139-140. https://doi.org/10.1111/nicc.12762

Welcome to our second issue for 2022. The aims and scope of Nursing in Critical specify that it caters for “the diverse specialities of critical care nursing including surgery, medicine, cardiac, renal, neurosciences, haematology, accident and emerge... Read More about Spotlight on cardiac intensive care nursing (Editorial).

Mindfulness-based interventions to reduce stress and burnout in nurses : an integrative review (2022)
Journal Article
Armstong, J., & Tume, L. (2022). Mindfulness-based interventions to reduce stress and burnout in nurses : an integrative review. British Journal of Mental Health Nursing, 11(1), 1-11. https://doi.org/10.12968/bjmh.2020.0036

Background With work-related stress and current COVID-19 pandemic, nurses are at heightened risk of stress and burnout. Mindfulness-based interventions (MBI) have been seen to decrease stress and burnout, yet research into the effectiveness for nurs... Read More about Mindfulness-based interventions to reduce stress and burnout in nurses : an integrative review.

Development, implementation and evaluation of an evidence-based paediatric early warning system improvement programme : the PUMA mixed methods study (2022)
Journal Article
Allen, D., Lloyd, A., Edwards, D., Hood, K., Huang, C., Hughes, J., …Roland, D. (2022). Development, implementation and evaluation of an evidence-based paediatric early warning system improvement programme : the PUMA mixed methods study. BMC Health Services Research, 22(1), 9. https://doi.org/10.1186/s12913-021-07314-2

Background: Paediatric mortality rates in the United Kingdom are amongst the highest in Europe. Clinically missed deterioration is a contributory factor. Evidence to support any single intervention to address this problem is limited, but a cumula... Read More about Development, implementation and evaluation of an evidence-based paediatric early warning system improvement programme : the PUMA mixed methods study.