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A free-response evaluation determining value in the computed tomography attenuation correction image for revealing pulmonary incidental findings : a phantom study (2014)
Journal Article
Thompson, J., Hogg, P., Manning, D., Szczepura, K., & Chakraborty, D. (2014). A free-response evaluation determining value in the computed tomography attenuation correction image for revealing pulmonary incidental findings : a phantom study. Academic radiology, 21(4), 538-545. https://doi.org/10.1016/j.acra.2014.01.003

RATIONALE AND OBJECTIVES: The purpose of this study was to compare lesion-detection performance when interpreting computed tomography (CT) images that are acquired for attenuation correction when performing single photon emission computed tomography/... Read More about A free-response evaluation determining value in the computed tomography attenuation correction image for revealing pulmonary incidental findings : a phantom study.

Fact or fiction : an analysis of the 10 kVp ‘rule’ in computed radiography (2013)
Journal Article
radiography. Radiography, 19(3), 223-227. https://doi.org/10.1016/j.radi.2013.05.003

Purpose: To determine whether increasing the tube voltage by 10 kVp whilst reducing the tube current by 50% (10 kVp ‘rule’) produces similar perceptual image quality. Method: 391 matched pairs of anthropomorphic chest phantom X-ray images were pro... Read More about Fact or fiction : an analysis of the 10 kVp ‘rule’ in computed radiography.

Tissue bulge during stereotactic core biopsy (2013)
Journal Article
Hackney, L., Williams, S., Hogg, P., & Szczepura, K. (2013). Tissue bulge during stereotactic core biopsy. Radiography, 19(4), 366-368. https://doi.org/10.1016/j.radi.2013.06.007

In full field digital mammography (FFDM) the whole breast is subjected to compression with a perspex compression paddle in order to reduce breast thickness and improve image quality. Once a mammographic abnormality has been detected using FFDM and a... Read More about Tissue bulge during stereotactic core biopsy.

Practitioner compression force variation in mammography : a 6 year study (2013)
Journal Article
Mercer, C., Hogg, P., Szczepura, K., & Denton, E. (2013). Practitioner compression force variation in mammography : a 6 year study. Radiography, 19(3), 200-206. https://doi.org/10.1016/j.radi.2013.06.001

The application of breast compression in mammography may be more heavily influenced by the practitioner rather than the client. This could affect image quality and will affect client experience. This study builds on previous research to establish i... Read More about Practitioner compression force variation in mammography : a 6 year study.

A method to measure paddle and detector pressures and footprints in mammography (2013)
Journal Article
Hogg, P., Szczepura, K., Darlington, A., & Maxwell, A. (2013). A method to measure paddle and detector pressures and footprints in mammography. Medical Physics, 40(4), 041907. https://doi.org/10.1118/1.4792720

Purpose: Compression is necessary in mammography to improve image quality and reduce radiation burden. Maximizing the amount of breast in contact with the image receptor (IR) is important. To achieve this, for the craniocaudal projection, there is n... Read More about A method to measure paddle and detector pressures and footprints in mammography.

Optimising the number of thermoluminescent dosimeters required for the measurement of effective dose for computed tomography attenuation correction data in SPECT/CT myocardial perfusion imaging (2013)
Journal Article
Tootell, A., Szczepura, K., & Hogg, P. (2013). Optimising the number of thermoluminescent dosimeters required for the measurement of effective dose for computed tomography attenuation correction data in SPECT/CT myocardial perfusion imaging. Radiography, 19(1), 42-47. https://doi.org/10.1016/j.radi.2012.11.001

Background The use of thermoluminescent dosimeters (TLDs) is regarded as time consuming and laborious. As part of our dosimetry research it was necessary to optimise the use of our resources, both physical and time. Experimental work was carried... Read More about Optimising the number of thermoluminescent dosimeters required for the measurement of effective dose for computed tomography attenuation correction data in SPECT/CT myocardial perfusion imaging.

Pressure and breast thickness in mammography : an exploratory calibration study (2013)
Journal Article
Hogg, P., Taylor, M., Szczepura, K., Mercer, C., & Denton, E. (2013). Pressure and breast thickness in mammography : an exploratory calibration study. British Journal of Radiology, 86(1021), 1-7. https://doi.org/10.1259/bjr.20120222

Objective To perform a calibration study to provide data to help improve consistency in the pressure that is applied during mammography. Methods Automatic readouts of breast thickness accuracy vary between mammography machines; therefore, one m... Read More about Pressure and breast thickness in mammography : an exploratory calibration study.

Analysis of CT acquisition parameters suitable for use in SPECT/CT : a free-response receiver operating characteristic study (2012)
Journal Article
Thompson, J., Hogg, P., Szczepura, K., & Manning, D. (2012). Analysis of CT acquisition parameters suitable for use in SPECT/CT : a free-response receiver operating characteristic study. Radiography, 18(4), 238-243. https://doi.org/10.1016/j.radi.2012.05.004

Purpose This dose optimisation free-response receiver operating characteristic (FROC) study compares the diagnostic performance of 8 CT acquisition parameter settings suitable for use with diagnostic quality SPECT/CT systems. Observers were requi... Read More about Analysis of CT acquisition parameters suitable for use in SPECT/CT : a free-response receiver operating characteristic study.

ROCView : prototype software for data collection in jackknife alternative free-response receiver operating characteristic analysis (2012)
Journal Article
Thompson, J., Hogg, P., Thompson, S., Manning, D., & Szczepura, K. (2012). ROCView : prototype software for data collection in jackknife alternative free-response receiver operating characteristic analysis. British Journal of Radiology, 85, 1320-1326. https://doi.org/10.1259/bjr/99497945

ROCView has been developed as an image display and response capture (IDRC) solution to image display and consistent recording of reader responses in relation to the free-response receiver operating characteristic paradigm. A web-based solution to IDR... Read More about ROCView : prototype software for data collection in jackknife alternative free-response receiver operating characteristic analysis.

The readout thickness versus the measured thickness for a range of screen film mammography (SFM) and full-field digital mammography (FFDM) units (2011)
Journal Article
Hauge, I., Hogg, P., Szczepura, K., Connolly, P., McGill, G., & Mercer, C. (2011). The readout thickness versus the measured thickness for a range of screen film mammography (SFM) and full-field digital mammography (FFDM) units. Medical Physics, 39(1), 263-271. https://doi.org/10.1118/1.3663579

PURPOSE: To establish a simple method to determine breast readout accuracy on mammography units. METHODS: A thickness measuring device (TMD) was used in conjunction with a breast phantom. This phantom had compression characteristics similar to human... Read More about The readout thickness versus the measured thickness for a range of screen film mammography (SFM) and full-field digital mammography (FFDM) units.

Prototype software for the clinical evaluation of In-111 SPECT-CT dotatate images conducted prior to and immediately after Y-90 dotatate radionuclide therapy (2011)
Journal Article
Hogg, P., Swire, V., Orlinksi, M., Blindell, P., Vinjamuri, S., & Szczepura, K. (2011). Prototype software for the clinical evaluation of In-111 SPECT-CT dotatate images conducted prior to and immediately after Y-90 dotatate radionuclide therapy. European Journal of Nuclear Medicine and Molecular Imaging, 38(Sup. 2), S447. https://doi.org/10.1007/s00259-011-1913-y

Aim and Background Neuroendocrine tumours (NETs) are heterogenous and frequently express cell membrane specific peptide receptors such as somatostatin receptors (SSTRs). Radiolabelled receptor binding of somatostatin analogues can guide radioact... Read More about Prototype software for the clinical evaluation of In-111 SPECT-CT dotatate images conducted prior to and immediately after Y-90 dotatate radionuclide therapy.

Analysis of plain X-ray and low resolution CT gonad dose arising from supplementary imaging after bone scanning (2011)
Journal Article
Kelly, J., Szczepura, K., Hogg, P., & Tootell, A. (2011). Analysis of plain X-ray and low resolution CT gonad dose arising from supplementary imaging after bone scanning. European Journal of Nuclear Medicine and Molecular Imaging, 38(Sup. 2), S445. https://doi.org/10.1007/s00259-011-1913-y

Introduction:Bone scintigraphy has long been the first stop for patients undergoing investigation of bone metastases. The procedure is recognised as being highly sensitive to the disease however this corresponds to a low specificity. As a result s... Read More about Analysis of plain X-ray and low resolution CT gonad dose arising from supplementary imaging after bone scanning.

Quantification of neutrophil migration into the lungs of patients with chronic obstructive pulmonary disease (2011)
Journal Article
Ruparelia, P., Szczepura, K., Summers, C., Solanki, C., Balan, K., Newbold, P., …Chilvers, E. (2011). Quantification of neutrophil migration into the lungs of patients with chronic obstructive pulmonary disease. European Journal of Nuclear Medicine and Molecular Imaging, 38(5), 911-919. https://doi.org/10.1007/s00259-010-1715-7

Objective: to quantify neutrophil migration into the lungs of patients with chronic pulmonary obstructive disease (COPD). Methods: neutrophil loss via airways was assessed by dedicated whole-body counting 45 min, 24 h and 2, 4, 7 and 10 days after... Read More about Quantification of neutrophil migration into the lungs of patients with chronic obstructive pulmonary disease.

Measuring whole-body neutrophil redistribution using a dedicated whole-body counter and ultra-low doses of 111 Indium (2011)
Journal Article
Szczepura, K., Ruparelia, P., Solanki, C., Balan, K., Newbold, P., Summers, C., …Peters, A. (2011). Measuring whole-body neutrophil redistribution using a dedicated whole-body counter and ultra-low doses of 111 Indium. European Journal of Clinical Investigation, 41(1), 77-83. https://doi.org/10.1111/j.1365-2362.2010.02382.x

Background - There is increasing interest in the ‘homing’ of neutrophils to bone marrow. The aim of this study was to measure the whole-body redistribution of 111In using a whole-body counter following the administration of ultra-small activities of... Read More about Measuring whole-body neutrophil redistribution using a dedicated whole-body counter and ultra-low doses of 111 Indium.

Determination of optimal CT exposure factors for lung lesions using an anthropomorphic chest phantom for SPECT-CT (2010)
Journal Article
Thompson, J., Szczepura, K., Tootell, A., Sil, J., Manning, D., & Hogg, P. (2010). Determination of optimal CT exposure factors for lung lesions using an anthropomorphic chest phantom for SPECT-CT. European Journal of Nuclear Medicine and Molecular Imaging, 37(Sup. 2), S494. https://doi.org/10.1007/s00259-010-1560-8

PURPOSE: SPECT‐CT is a valuable modality for diagnosis and staging of primary and secondary malignant disease and also diagnosing benign conditions. CT incurs a significant radiation burden; consequently CT acquisition parameters require optimisati... Read More about Determination of optimal CT exposure factors for lung lesions using an anthropomorphic chest phantom for SPECT-CT.

Does P-glycoprotein have a role in the lung clearances of inhaled 99m Tc-sestamibi and 99m Tc-tetrofosmin? (2009)
Journal Article
Cheow, H., Ruparelia, P., Shankar, S., Szczepura, K., Ballinger, J., Hartman, N., …Peters, A. (2009). Does P-glycoprotein have a role in the lung clearances of inhaled 99m Tc-sestamibi and 99m Tc-tetrofosmin?. Nuclear Medicine Communications, 30(8), 617-621. https://doi.org/10.1097/MNM.0b013e32832b9a2d

Objective - The clearance rate of inhaled 99mTc-sestamibi from the lungs of healthy nonsmoking individuals is much slower than would be expected from its physical properties. The clearance rate is even slower in healthy cigarette smokers. As 99mTc-s... Read More about Does P-glycoprotein have a role in the lung clearances of inhaled 99m Tc-sestamibi and 99m Tc-tetrofosmin?.

Does P-glycoprotein have a role in the lung clearances of inhaled 99mTc-sestamibi and 99mTc-tetrofosmin? (2009)
Journal Article
Cheow, H., Ruparelia, P., Shankar, S., Szczepura, K., Ballinger, J., Hartman, N., …Michael Peters, A. (2009). Does P-glycoprotein have a role in the lung clearances of inhaled 99mTc-sestamibi and 99mTc-tetrofosmin?. Nuclear Medicine Communications, 30(8), 617-621. https://doi.org/10.1097/mnm.0b013e32832b9a2d

Objective The clearance rate of inhaled 99mTc-sestamibi from the lungs of healthy nonsmoking individuals is much slower than would be expected from its physical properties. The clearance rate is even slower in healthy cigarette smokers. As 99mTc-se... Read More about Does P-glycoprotein have a role in the lung clearances of inhaled 99mTc-sestamibi and 99mTc-tetrofosmin?.