The role of mathematical modeling in understanding aging
(2017)
Book Chapter
Dr Mark McAuley's Outputs (3)
LDL-C levels in older people: Cholesterol homeostasis and the free radical theory of ageing converge (2017)
Journal Article
The cardiovascular disease (CVD) risk factor, low density lipoprotein cholesterol (LDL-C) increases with age, up until the midpoint of life in males and females. However, LDL-C can decrease with age in older men and women. Intriguingly, a recent syst... Read More about LDL-C levels in older people: Cholesterol homeostasis and the free radical theory of ageing converge.
Modelling the molecular mechanisms of aging (2017)
Journal Article
Mc Auley, M., Guimera, A., Hodgson, D., Mcdonald, N., Mooney, K., Morgan, A., & Proctor, C. (2017). Modelling the molecular mechanisms of aging. Bioscience Reports, 37(1), https://doi.org/10.1042/BSR20160177The aging process is driven at the cellular level by random molecular damage that slowly accumulates with age. Although cells possess mechanisms to repair or remove damage, they are not 100% efficient and their efficiency declines with age. There are... Read More about Modelling the molecular mechanisms of aging.