Measurement of 4-hydroxy-2,2,6,6-tetramethyl-piperidine-N-oxyl by high performance liquid chromatography-electrospray ionisation mass spectrometry (2002)
Journal Article
Podmore, I. (2002). Measurement of 4-hydroxy-2,2,6,6-tetramethyl-piperidine-N-oxyl by high performance liquid chromatography-electrospray ionisation mass spectrometry. Journal of Chemical Research, 574-575. https://doi.org/10.3184/030823402103170835

Reverse phase high performance liquid chromatography coupled to electrospray ionisation mass spectrometry and tandem mass spectrometry has allowed quantitative measurement of a stable nitroxide, 4-hydroxy-2,2,6,6-tetramethyl-piperidine-N-oxyl (4-hydr... Read More about Measurement of 4-hydroxy-2,2,6,6-tetramethyl-piperidine-N-oxyl by high performance liquid chromatography-electrospray ionisation mass spectrometry.

Molecular imaging and biological evaluation of HuMV833 anti-VEGF antibody: implications for trial design of antiangiogenic antibodies (2002)
Journal Article
Jayson, G., Zweit, J., Jackson, A., Mulatero, C., Julyan, P., Ranson, M., …Zwierzina, H. (2002). Molecular imaging and biological evaluation of HuMV833 anti-VEGF antibody: implications for trial design of antiangiogenic antibodies. https://doi.org/10.1093/jnci/94.19.1484

Background: Vascular endothelial growth factor (VEGF) is a potent angiogenic cytokine, and various inhibitory agents, including specific antibodies, have been developed to block VEGF-stimulated angiogenesis. We developed HuMV833, a humanized vers... Read More about Molecular imaging and biological evaluation of HuMV833 anti-VEGF antibody: implications for trial design of antiangiogenic antibodies.

Rapid dot-ELISA for the detection of specific antigens in the cyst fluid from human cases of cystic echinococcosis. (2002)
Journal Article
Wang, Y., Bradshaw, H., Rogan, M., & Craig, P. (2002). Rapid dot-ELISA for the detection of specific antigens in the cyst fluid from human cases of cystic echinococcosis. Annals of Tropical Medicine and Parasitology, 96(7), 691-694. https://doi.org/10.1179/000349802125001717

A rapid dot-ELISA was developed for the detection of specific antigens in samples of cyst fluid from human cases of Echinococcus granulosus infection, permitting the confirmation of cystic echinococcosis (CE). Peroxidase-conjugated antibodies against... Read More about Rapid dot-ELISA for the detection of specific antigens in the cyst fluid from human cases of cystic echinococcosis..

Direct modulation of the effective sensitivity of a CCD detector: a new approach to time-resolved fluorescence imaging (2002)
Journal Article
Mitchell, A., Wall, J., Murray, J., & Morgan, C. (2002). Direct modulation of the effective sensitivity of a CCD detector: a new approach to time-resolved fluorescence imaging. Journal of Microscopy, 206(3), 225-232. https://doi.org/10.1046/j.1365-2818.2002.01029.x

In this paper a novel approach to frequency-domain fluorescence lifetime imaging (FLIM) is described. In a CCD camera a single pixel is defined by a charge pattern on a group of electrodes. By modulation of the pattern of voltages defining the pixel... Read More about Direct modulation of the effective sensitivity of a CCD detector: a new approach to time-resolved fluorescence imaging.

Measurement of nanosecond time-resolved fluorescence with a directly gated interline CCD camera (2002)
Journal Article
Mitchell, A., Wall, J., Murray, J., & Morgan, C. (2002). Measurement of nanosecond time-resolved fluorescence with a directly gated interline CCD camera. Journal of Microscopy, 206(3), 233-238. https://doi.org/10.1046/j.1365-2818.2002.01030.x

CCD cameras coupled optically to gated image intensifiers have been used for fast time-resolved measurements for some years. Image intensifiers have disadvantages, however, and for some applications it would be better if the image sensor could be gat... Read More about Measurement of nanosecond time-resolved fluorescence with a directly gated interline CCD camera.

Repair of dihydrouracil supported by base excision repair in mNTH1 knock-out cell extracts (2002)
Journal Article
Elder, R., & Dianov, G. (2002). Repair of dihydrouracil supported by base excision repair in mNTH1 knock-out cell extracts. Journal of Biological Chemistry, 277(52), 50487-90. https://doi.org/10.1074/jbc.M208153200

In mammalian cells, thymine glycols and other oxidized pyrimidines such as 5,6-dihydrouracil are removed from DNA by the NTH1 protein, a bifunctional DNA-N-glycosylase. However, mNTH1 knock-out mice in common with other DNA glycosylase-deficient mice... Read More about Repair of dihydrouracil supported by base excision repair in mNTH1 knock-out cell extracts.

Monte Carlo simulations of polyion−macroion complexes. 1. Equal absolute polyion and macroion charges (2002)
Journal Article
Akinshina, A., & Linse, P. (2002). Monte Carlo simulations of polyion−macroion complexes. 1. Equal absolute polyion and macroion charges. Macromolecules, 35(13), 5183-5193. https://doi.org/10.1021/ma012052u

Intermolecular structures of complexes formed between a charged polymer and a spherical and oppositely charged macroion have been studied by employing the primitive model solved by Monte Carlo simulations. The strong-complex case involving a polyio... Read More about Monte Carlo simulations of polyion−macroion complexes. 1. Equal absolute polyion and macroion charges.