Gold-ligand interaction studies of water-soluble aminoalcohol capped gold nanoparticles by NMR (2008)
Journal Article
Porta, F., Krpetic, Z., Prati, L., Gaiassi, A., & Scarì, G. (2008). Gold-ligand interaction studies of water-soluble aminoalcohol capped gold nanoparticles by NMR. Langmuir, 24(14), 7061-7064. https://doi.org/10.1021/la8008392

Novel reproducible preparations of gold nanoparticles capped by aminoalcohols have been set up by reduction of HAuCl4 with NaBH4 in aqueous solution. The characterization of Au@aminoalcohol nanoparticles performed by 1H NMR, ATR-FTIR, UV−vis spectros... Read More about Gold-ligand interaction studies of water-soluble aminoalcohol capped gold nanoparticles by NMR.

Effect of O6-methylguanine on the stability of G-quadruplex DNA (2008)
Journal Article
Mekmaysy, C., Petraccome, L., Garbett, N., Ragazzon, P., Gray, R., Trent, J., & Chaires, J. (2008). Effect of O6-methylguanine on the stability of G-quadruplex DNA. Abstracts of papers / American Chemical Society, 130(21), 6710-6711. https://doi.org/10.1021/ja801976h

The effects of substitution of O6-methylguanine on the structure and stability of a human telomere quadruplex was studied by circular dichroism, thermal denaturation, analytical ultracentrifugation, and molecular dynamics simulations. The results sho... Read More about Effect of O6-methylguanine on the stability of G-quadruplex DNA.

Real-time cellular uptake of serotonin using fluorescence lifetime imaging with two-photon excitation (2008)
Journal Article
Botchway, S., Parker, A., Bisby, R., & Crisostomo, A. (2008). Real-time cellular uptake of serotonin using fluorescence lifetime imaging with two-photon excitation. Microscopy Research and Technique, 71(4), 267-273. https://doi.org/10.1002/jemt.20548

The real-time uptake of serotonin, a neurotransmitter, by rat leukaemia mast cell line RBL-2H3 and 5-hydroxytryptophan by Chinese hamster V79 cells has been studied by fluorescence lifetime imaging microscopy (FLIM), monitoring ultraviolet (340 nm) f... Read More about Real-time cellular uptake of serotonin using fluorescence lifetime imaging with two-photon excitation.

Chemical composition and flavour development of cocoa products by thermal and enzymatic technologies (2008)
Thesis
Miralles-Garcia, J. Chemical composition and flavour development of cocoa products by thermal and enzymatic technologies. (Thesis). University of Salford

A novel technology to process traditional chocolate-making ingredients has been investigated with the main objective to promote the generation of key chocolate odorant volatiles as a part of the commercial interest of the industrial partner to create... Read More about Chemical composition and flavour development of cocoa products by thermal and enzymatic technologies.

Effect of antioxidant potential in the oxygen radical absorption capacity (ORAC) assay (2008)
Journal Article
Bisby, R., Brooke, R., & Navaratnam, S. (2008). Effect of antioxidant potential in the oxygen radical absorption capacity (ORAC) assay. Food Chemistry, 108(3), 1002-1007. https://doi.org/10.1016/j.foodchem.2007.12.012

The "Oxygen Radical Absorption Capacity” (ORAC) assay (Ou, B., Hampsch-Woodill, M., Prior, R.L. (2001). Development and validation of an improved oxygen radical absorbance capacity assay using fluorescein as the fluorescent probe. Journal of Agricultur... Read More about Effect of antioxidant potential in the oxygen radical absorption capacity (ORAC) assay.

Novel therapeutic strategies by regulatory T cells in allergy (2008)
Book Chapter
Elkord, E. (2008). Novel therapeutic strategies by regulatory T cells in allergy. In K. Blaser (Ed.), T Cell Regulation in Allergy, Asthma and Atopic Skin Diseases (150-157). Chemical Immunology and Allergy: Karger. https://doi.org/10.1159/000154999

Natural CD4+CD25+FoxP3+ regulatory T cells (Treg) actively suppress physiological and pathological responses, therefore playing a critical role in controlling peripheral tolerance to self antigens and maintaining immune homeostasis. In normal individ... Read More about Novel therapeutic strategies by regulatory T cells in allergy.

Clinical and immunologic results of a phase II trial of sequential imiquimod and photodynamic therapy for vulval intraepithelial neoplasia (2008)
Journal Article
Winters, U., Daayana, S., Lear, J., Tomlinson, A., Elkord, E., Stern, P., & Kitchener, H. (2008). Clinical and immunologic results of a phase II trial of sequential imiquimod and photodynamic therapy for vulval intraepithelial neoplasia. Clinical Cancer Research, 14(16), 5292-5299. https://doi.org/10.1158/1078-0432.CCR-07-4760

PURPOSE: High-risk human papillomavirus (HPV)-associated vulval intraepithelial neoplasia (VIN) is difficult to treat by excision or ablation because of high recurrence rates. Small studies of photodynamic therapy (PDT) and imiquimod treatments have... Read More about Clinical and immunologic results of a phase II trial of sequential imiquimod and photodynamic therapy for vulval intraepithelial neoplasia.

Immunotherapy for gastrointestinal cancer: current status and strategies for improving efficacy (2008)
Journal Article
Elkord, E., Hawkins, R., & Stern, P. (2008). Immunotherapy for gastrointestinal cancer: current status and strategies for improving efficacy. Expert Opinion on Biological Therapy, 8(4), 385-395. https://doi.org/10.1517/14712598.8.4.385

BACKGROUND: Despite improvement in conventional strategies for treating gastrointestinal (GI) carcinoma, large numbers of patients still suffer from incurable or progressive disease. OBJECTIVE: Here we consider the prospects for circumventing limi... Read More about Immunotherapy for gastrointestinal cancer: current status and strategies for improving efficacy.

CD4+ T-cell recognition of human 5T4 oncofoetal antigen: implications for initial depletion of CD25+ T cells (2008)
Journal Article
Elkord, E., Burt, D., Drijfhout, J., Hawkins, R., & Stern, P. (2008). CD4+ T-cell recognition of human 5T4 oncofoetal antigen: implications for initial depletion of CD25+ T cells. Cancer Immunology, Immunotherapy, 57(6), 833-847. https://doi.org/10.1007/s00262-007-0419-8

BACKGROUND: The human 5T4 (h5T4) oncofoetal antigen is expressed by a wide variety of human carcinomas including colorectal, ovarian, gastric and renal, but rarely on normal tissues. Its restricted expression on tumour tissues as well as its associat... Read More about CD4+ T-cell recognition of human 5T4 oncofoetal antigen: implications for initial depletion of CD25+ T cells.

Adoptive transfer of T(reg) depleted autologous T cells in advanced renal cell carcinoma (2008)
Journal Article
Thistlethwaite, F., Elkord, E., Griffiths, R., Burt, D., Shablak, A., Campbell, J., …Hawkins, R. (2008). Adoptive transfer of T(reg) depleted autologous T cells in advanced renal cell carcinoma. Cancer Immunology, Immunotherapy, 57(5), 623-634. https://doi.org/10.1007/s00262-007-0400-6

PURPOSE: CD4(+)CD25(+) regulatory T (T(reg)) cells are present in increased numbers in patients with advanced cancer and CD25(+) T cell depletion potentiates tumour immunity in animal models. The aim of this study was to assess the feasibility and sa... Read More about Adoptive transfer of T(reg) depleted autologous T cells in advanced renal cell carcinoma.

The porin and the permeating antibiotic: A selective diffusion barrier in gram-negative bacteria (2008)
Journal Article
Pages, J., James, C., & Winterhalter, M. (2008). The porin and the permeating antibiotic: A selective diffusion barrier in gram-negative bacteria. Nature Reviews Microbiology, 6, 893-903. https://doi.org/10.1038/nrmicro1994

Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm. The outer membran... Read More about The porin and the permeating antibiotic: A selective diffusion barrier in gram-negative bacteria.

Membrane permeability and regulation of drug "influx and efflux" in enterobacterial pathogens. (2008)
Journal Article
Davin-Regli, A., Bolla, J., James, C., Lavigne, J., Chevalier, J., Garnotel, E., …Pagès, J. (2008). Membrane permeability and regulation of drug "influx and efflux" in enterobacterial pathogens. Current Drug Targets, 9(9), 750-759. https://doi.org/10.2174/138945008785747824

In Enterobacteriaceae, membrane permeability is a key in the level of susceptibility to antibiotics. Modification of the bacterial envelope by decreasing the porin production or increasing the expression of efflux pump systems has been reported. Thes... Read More about Membrane permeability and regulation of drug "influx and efflux" in enterobacterial pathogens..

Interactions between adsorbed layers of αS1-Casein with covalently bound side chains : a self-consistent field study (2008)
Journal Article
Akinshina, A., Ettelaie, R., Dickinson, E., & Smyth, G. (2008). Interactions between adsorbed layers of αS1-Casein with covalently bound side chains : a self-consistent field study. Biomacromolecules, 9(11), 3188-3200. https://doi.org/10.1021/bm800771t

The effect on the adsorbed layer properties of the modification of αS1-casein by covalent bonding with an uncharged polysaccharide side chain has been investigated using lattice-based self-consistent field (SCF) theory. Interactions between two hydro... Read More about Interactions between adsorbed layers of αS1-Casein with covalently bound side chains : a self-consistent field study.

Mixed protein–polysaccharide interfacial layers : a self consistent field calculation study (2008)
Journal Article
Ettelaie, R., Akinshina, A., & Dickinson, E. (2008). Mixed protein–polysaccharide interfacial layers : a self consistent field calculation study. Faraday Discussions, 139, 161. https://doi.org/10.1039/B717199D

Mixed interfacial films of protein and polysaccharide have been investigated using self consistent field (SCF) calculations. The colloidal interactions mediated by such composite layers between two approaching surfaces have been considered. Two types... Read More about Mixed protein–polysaccharide interfacial layers : a self consistent field calculation study.