School of Science, Engineering & Environment

Differences in iNOS and arginase expression and activity in the macrophages of rats are responsible for the resistance against T. gondii infection (2012)
Journal Article
Gruner, A., Li, Z., Zhao, Z., Zhu, X., Ren, Q., Nie, F., …Lun, Z. (2012). Differences in iNOS and arginase expression and activity in the macrophages of rats are responsible for the resistance against T. gondii infection. PLoS ONE, 7(4), e35834. https://doi.org/10.1371/journal.pone.0035834

Toxoplasma gondii infects humans and warm blooded animals causing devastating disease worldwide. It has long been a mystery as to why the peritoneal macrophages of rats are naturally resistant to T. gondii infection while those of mice are not. Her... Read More about Differences in iNOS and arginase expression and activity in the macrophages of rats are responsible for the resistance against T. gondii infection.

Toxoplasma gondii infection in pregnant women in China. (2011)
Journal Article
XJ, G., ZJ, Z., ZH, H., T, W., TB, Y., XG, C., …ZR, L. (2012). Toxoplasma gondii infection in pregnant women in China. Parasitology, 139(2), https://doi.org/10.1017/S0031182011001880

Toxoplasmosis, caused by the protozoan parasite Toxoplasma gondii, is one of the most common parasitic infections in humans. Primary infection in pregnant women can be transmitted to the fetus leading to miscarriage or congenital toxoplasmosis. Caref... Read More about Toxoplasma gondii infection in pregnant women in China..

Genotyping of Toxoplasma gondii isolates from cats in different geographic regions of China. (2011)
Journal Article
ZW, C., JM, G., XX, H., L, W., L, Y., F, H.-L., …ZR, L. (2011). Genotyping of Toxoplasma gondii isolates from cats in different geographic regions of China. Veterinary Parasitology, 183(1-2), 166-170. https://doi.org/10.1016/j.vetpar.2011.06.013

Fourteen isolates of Toxoplamsa gondii were isolated from cats from 4 different geographic provinces (Anhui, Hubei, Shanxi and Guangdong) in China and their genetic diversity with 8 nuclear loci SAG2, SAG3, BTUB, GRA6, L358, PK1, c22-8, c29-2, and an... Read More about Genotyping of Toxoplasma gondii isolates from cats in different geographic regions of China..

Prevalence and co-infection of Toxoplasma gondii and Neospora caninum in Apodemus sylvaticus in an area relatively free of cats (2011)
Journal Article
Thomasson, D., Wright, E., Hughes, J., Dodd, N., Cox, A., Boyce, K., …Hide, G. (2011). Prevalence and co-infection of Toxoplasma gondii and Neospora caninum in Apodemus sylvaticus in an area relatively free of cats. Parasitology, 138(09), 1117-1123. https://doi.org/10.1017/S0031182011000904

The protozoan parasite Toxoplasma gondii is prevalent worldwide and can infect a remarkably wide range of hosts despite felids being the only definitive host. As cats play a major role in transmission to secondary mammalian hosts, the interaction b... Read More about Prevalence and co-infection of Toxoplasma gondii and Neospora caninum in Apodemus sylvaticus in an area relatively free of cats.

The best practice for preparation of samples from FTA®cards for diagnosis of blood borne infections using African trypanosomes as a model system (2011)
Journal Article
Ahmed, H., MacLeod, E., Hide, G., Welburn, S., & Picozzi, K. (2011). The best practice for preparation of samples from FTA®cards for diagnosis of blood borne infections using African trypanosomes as a model system. Parasites and Vectors, 4, 68. https://doi.org/10.1186/1756-3305-4-68

Background: Diagnosis of blood borne infectious diseases relies primarily on the detection of the causative agent in the blood sample. Molecular techniques offer sensitive and specific tools for this although considerable difficulties exist when us... Read More about The best practice for preparation of samples from FTA®cards for diagnosis of blood borne infections using African trypanosomes as a model system.

Constraints to estimating the prevalence of trypanosome infections in East African zebu cattle (2010)
Journal Article
Cox, A., Tosas, O., Tilley, A., Picozzi, K., Coleman, P., Hide, G., & Welburn, S. (2010). Constraints to estimating the prevalence of trypanosome infections in East African zebu cattle. Parasites and Vectors, 3(1), 82

In East Africa, animal trypanosomiasis is caused by many tsetse transmitted protozoan parasites including Trypanosoma vivax, T. congolense and subspecies of T. brucei s.l. (T. b. brucei and zoonotic human infective T. b. rhodesiense) that may co-circ... Read More about Constraints to estimating the prevalence of trypanosome infections in East African zebu cattle.

Molecular epidemiology of African sleeping sickness (2009)
Journal Article
Hide, G., & Tait, A. (2009). Molecular epidemiology of African sleeping sickness. Parasitology, 136(12), 1491-500. https://doi.org/10.1017/S0031182009990333

Human sleeping sickness in Africa, caused by Trypanosoma brucei spp. raises a number of questions. Despite the widespread distribution of the tsetse vectors and animal trypanosomiasis, human disease is only found in discrete foci which periodically g... Read More about Molecular epidemiology of African sleeping sickness.

Evidence for high levels of vertical transmission in Toxoplasma gondii (2009)
Journal Article
Hide, G., Morley, E., Hughes, J., Gerwash, O., Elmahaishi, M., Elmahaishi, K., …Smith, J. (2009). Evidence for high levels of vertical transmission in Toxoplasma gondii. Parasitology, 136(14), 1877-85. https://doi.org/10.1017/S0031182009990941

Toxoplasma gondii is a highly ubiquitous and prevalent parasite. Despite the cat being the only definitive host, it is found in almost all geographical areas and warm blooded animals. Three routes of transmission are recognised: ingestion of oocysts... Read More about Evidence for high levels of vertical transmission in Toxoplasma gondii.

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