All Outputs (107)

Naturally occurring Toll-like receptor 11 (TLR11) and Toll-like receptor 12 (TLR12) polymorphisms are not associated with Toxoplasma gondii infection in wild wood mice (2014)
Journal Article
Morger, J., Bajnok, J., Boyce, K., Craig, P., Rogan, M., Lun, Z., …Tschirren, B. (2014). Naturally occurring Toll-like receptor 11 (TLR11) and Toll-like receptor 12 (TLR12) polymorphisms are not associated with Toxoplasma gondii infection in wild wood mice. Infection, Genetics and Evolution, 26, 180-184. https://doi.org/10.1016/j.meegid.2014.05.032

Toxoplasma gondii is a highly successful parasite with a worldwide prevalence. Small rodents are the main intermediate hosts, and there is growing evidence that T. gondii modifies their behaviour. Chronically infected rodents show impaired learning... Read More about Naturally occurring Toll-like receptor 11 (TLR11) and Toll-like receptor 12 (TLR12) polymorphisms are not associated with Toxoplasma gondii infection in wild wood mice.

Naturally occurring Toll-like receptor 11 (TLR11) and Toll-like receptor 12 (TLR12) polymorphisms are not associated with Toxoplasma gondii infection in wild wood mice (2014)
Journal Article
Morger, J., Bajnok, J., Boyce, K., Craig, P., Rogan, M., Lun, Z., …Tschirren, B. (2014). Naturally occurring Toll-like receptor 11 (TLR11) and Toll-like receptor 12 (TLR12) polymorphisms are not associated with Toxoplasma gondii infection in wild wood mice. Infection, Genetics and Evolution, 26, 180-184

Toxoplasma gondii is a highly successful parasite with a worldwide prevalence. Small rodents are the main intermediate hosts, and there is growing evidence that T. gondii modifies their behaviour. Chronically infected rodents show impaired learning c... Read More about Naturally occurring Toll-like receptor 11 (TLR11) and Toll-like receptor 12 (TLR12) polymorphisms are not associated with Toxoplasma gondii infection in wild wood mice.

Toxoplasma gondii: Prevalence in species and genotypes of British bats (Pipistrellus pipistrellus and P. pygmaeus) (2014)
Journal Article
Dodd, N. S., Lord, J. S., Jehle, R., Parker, S., Parker, F., Brooks, D. R., & Hide, G. (2014). Toxoplasma gondii: Prevalence in species and genotypes of British bats (Pipistrellus pipistrellus and P. pygmaeus). Experimental Parasitology, 139, 6-11. https://doi.org/10.1016/j.exppara.2014.02.007

Few studies have investigated Toxoplasma gondii infections in bat populations and none have reported its presence in protected British bat species. Using a collection of dead/euthanased bats collected from Lancashire, UK, two species of bats (Pipis... Read More about Toxoplasma gondii: Prevalence in species and genotypes of British bats (Pipistrellus pipistrellus and P. pygmaeus).

Toxoplasma gondii : prevalence in species and genotypes of British bats (Pipistrellus pipistrellus and P. pygmaeus) (2014)
Journal Article
Dodd, N., Lord, J., Jehle, R., Parker, S., Parker, F., Brooks, D., & Hide, G. (2014). Toxoplasma gondii : prevalence in species and genotypes of British bats (Pipistrellus pipistrellus and P. pygmaeus). Experimental Parasitology, 139, 6-11. https://doi.org/10.1016/j.exppara.2014.02.007

Few studies have investigated Toxoplasma gondii infections in bat populations and none have reported its presence in protected British bat species. Using a collection of dead/euthanased bats collected from Lancashire, UK, two species of bats (Pipis... Read More about Toxoplasma gondii : prevalence in species and genotypes of British bats (Pipistrellus pipistrellus and P. pygmaeus).

Toxoplasma gondii infection in the peritoneal macrophages of rats treated with glucocorticoids (2013)
Journal Article
Wang, T., Gao, J., Yi, S., Geng, G., Gao, X., Shen, J., …Lun, Z. (2014). Toxoplasma gondii infection in the peritoneal macrophages of rats treated with glucocorticoids. Parasitology Research, 113(1), 351-358. https://doi.org/10.1007/s00436-013-3661-3

It is well known that toxoplasmosis can be life threatening to immunocompromised individuals such as AIDS and organ transplantation patients. Glucocorticoids (GCs) are widely used in the clinic for the treatment of autoimmune diseases and organ t... Read More about Toxoplasma gondii infection in the peritoneal macrophages of rats treated with glucocorticoids.

Development and evaluation of loop-mediated isothermal amplification (LAMP) for rapid detection of Clonorchis sinensis from its first intermediate hosts, freshwater snails. (2013)
Journal Article
Y, C., T, W., DH, L., YZ, W., ZD, W., TB, Y., …ZR, L. (2013). Development and evaluation of loop-mediated isothermal amplification (LAMP) for rapid detection of Clonorchis sinensis from its first intermediate hosts, freshwater snails. Parasitology, 140(11), https://doi.org/10.1017/S0031182013000498

Clonorchiasis, caused by Clonorchis sinensis, is a key foodborne zoonosis, which is mainly found in China, Korea and Vietnam. Detection of this parasite from the second intermediate host, the freshwater fish is the common method for epidemiological s... Read More about Development and evaluation of loop-mediated isothermal amplification (LAMP) for rapid detection of Clonorchis sinensis from its first intermediate hosts, freshwater snails..

Lower expression of inducible nitric oxide synthase and higher expression of arginase in rat alveolar macrophages are linked to their susceptibility to Toxoplasma gondii infection. (2013)
Journal Article
ZJ, Z., J, Z., J, W., Z, L., T, W., SQ, Y., …ZR, L. (2013). Lower expression of inducible nitric oxide synthase and higher expression of arginase in rat alveolar macrophages are linked to their susceptibility to Toxoplasma gondii infection. PLoS ONE, https://doi.org/10.1371/journal.pone.0063650

Rats are naturally resistant to Toxoplasma gondii infection, particularly the RH strain, while mice are not. Previous studies have demonstrated that inducible nitric oxide synthase (iNOS) and arginase-1 of rodent peritoneal macrophages are linked to... Read More about Lower expression of inducible nitric oxide synthase and higher expression of arginase in rat alveolar macrophages are linked to their susceptibility to Toxoplasma gondii infection..

A molecular and ecological analysis of the trematode plagiorchis elegans in the wood mouse apodemus sylvaticus from a periaquatic ecosystem in the UK (2013)
Journal Article
Boyce, K., Hide, G., Craig, P., Reynolds, C., Hussain, M., Bodell, A., …Rogan, M. (2013). A molecular and ecological analysis of the trematode plagiorchis elegans in the wood mouse apodemus sylvaticus from a periaquatic ecosystem in the UK. Journal of Helminthology, 88(03), 310-320. https://doi.org/10.1017/S0022149X13000199

The prevalence of the digenean Plagiorchis sp. was investigated in a natural wood mouse population (Apodemus sylvaticus) in a periaquatic environment. Classical identification was complemented with the use of molecular differentiation to determine... Read More about A molecular and ecological analysis of the trematode plagiorchis elegans in the wood mouse apodemus sylvaticus from a periaquatic ecosystem in the UK.

Human parasitology - book review (2013)
Journal Article
Hide, G. (2013). Human parasitology - book review. British Journal of Biomedical Science, 70(4), 184-184

Identification of a new species of digenean Notocotylus malhamensis n. sp. (Digenea: Notocotylidae) from the bank vole (Myodes glareolus) and the field vole (Microtus agrestis) (2012)
Journal Article
vole (Myodes glareolus) and the field vole (Microtus agrestis). Parasitology, 139(12), 1630-1639. https://doi.org/10.1017/S0031182012000911

Notocotylus malhamensis n. sp. is described from the caecum of the bank vole (Myodes glareolus) and the field vole (Microtus agrestis) from Malham Tarn Nature Reserve in North Yorkshire, UK. In total, 581 specimens were collected from rodents trapp... Read More about Identification of a new species of digenean Notocotylus malhamensis n. sp. (Digenea: Notocotylidae) from the bank vole (Myodes glareolus) and the field vole (Microtus agrestis).

Detection of Trypanosoma lewisi from wild rats in Southern China and its genetic diversity based on the ITS1 and ITS2 sequences (2012)
Journal Article
Tang, H., Lan, Y., Wen, Y., Zhang, X., Desquesnes, M., Yang, T., …Lun, Z. (2012). Detection of Trypanosoma lewisi from wild rats in Southern China and its genetic diversity based on the ITS1 and ITS2 sequences. Infection, Genetics and Evolution, 12(5), 1046-1051. https://doi.org/10.1016/j.meegid.2012.02.018

Trypanosoma lewisi has widely been considered as a non-pathogenic rat trypanosome. However, more and more cases of humans infected with T. lewisi have been reported around the world, indicating that it can infect humans in some undetermined circums... Read More about Detection of Trypanosoma lewisi from wild rats in Southern China and its genetic diversity based on the ITS1 and ITS2 sequences.

Differences in iNOS and arginase expression and activity in the macrophages of rats are responsible for the resistance against T. gondii infection (2012)
Journal Article
Gruner, A., Li, Z., Zhao, Z., Zhu, X., Ren, Q., Nie, F., …Lun, Z. (2012). Differences in iNOS and arginase expression and activity in the macrophages of rats are responsible for the resistance against T. gondii infection. PLoS ONE, 7(4), e35834. https://doi.org/10.1371/journal.pone.0035834

Toxoplasma gondii infects humans and warm blooded animals causing devastating disease worldwide. It has long been a mystery as to why the peritoneal macrophages of rats are naturally resistant to T. gondii infection while those of mice are not. Her... Read More about Differences in iNOS and arginase expression and activity in the macrophages of rats are responsible for the resistance against T. gondii infection.

Toxoplasma gondii infection in pregnant women in China. (2011)
Journal Article
XJ, G., ZJ, Z., ZH, H., T, W., TB, Y., XG, C., …ZR, L. (2012). Toxoplasma gondii infection in pregnant women in China. Parasitology, 139(2), https://doi.org/10.1017/S0031182011001880

Toxoplasmosis, caused by the protozoan parasite Toxoplasma gondii, is one of the most common parasitic infections in humans. Primary infection in pregnant women can be transmitted to the fetus leading to miscarriage or congenital toxoplasmosis. Caref... Read More about Toxoplasma gondii infection in pregnant women in China..

Genotyping of Toxoplasma gondii isolates from cats in different geographic regions of China. (2011)
Journal Article
ZW, C., JM, G., XX, H., L, W., L, Y., F, H., …ZR, L. (2011). Genotyping of Toxoplasma gondii isolates from cats in different geographic regions of China. Veterinary Parasitology, 183(1-2), 166-170. https://doi.org/10.1016/j.vetpar.2011.06.013

Fourteen isolates of Toxoplamsa gondii were isolated from cats from 4 different geographic provinces (Anhui, Hubei, Shanxi and Guangdong) in China and their genetic diversity with 8 nuclear loci SAG2, SAG3, BTUB, GRA6, L358, PK1, c22-8, c29-2, and an... Read More about Genotyping of Toxoplasma gondii isolates from cats in different geographic regions of China..

An investigation in congenital transmission of Toxoplasma gondii as a potential mode of transmission in mice and humans (2011)
Thesis
Thomasson, D. An investigation in congenital transmission of Toxoplasma gondii as a potential mode of transmission in mice and humans. (Thesis). Salford : University of Salford

Toxoplasma gondii is a pathogenic Apicomplexan parasite with a worldwide distribution in almost all warm blooded animals. The parasite is transmitted to hosts in three ways; via oocysts that are passed from the definitive host the cat; by the... Read More about An investigation in congenital transmission of Toxoplasma gondii as a potential mode of transmission in mice and humans.

Prevalence and co-infection of Toxoplasma gondii and Neospora caninum in Apodemus sylvaticus in an area relatively free of cats (2011)
Journal Article
Thomasson, D., Wright, E., Hughes, J., Dodd, N., Cox, A., Boyce, K., …Hide, G. (2011). Prevalence and co-infection of Toxoplasma gondii and Neospora caninum in Apodemus sylvaticus in an area relatively free of cats. Parasitology, 138(09), 1117-1123. https://doi.org/10.1017/S0031182011000904

The protozoan parasite Toxoplasma gondii is prevalent worldwide and can infect a remarkably wide range of hosts despite felids being the only definitive host. As cats play a major role in transmission to secondary mammalian hosts, the interaction b... Read More about Prevalence and co-infection of Toxoplasma gondii and Neospora caninum in Apodemus sylvaticus in an area relatively free of cats.

The best practice for preparation of samples from FTA®cards for diagnosis of blood borne infections using African trypanosomes as a model system (2011)
Journal Article
Ahmed, H., MacLeod, E., Hide, G., Welburn, S., & Picozzi, K. (2011). The best practice for preparation of samples from FTA®cards for diagnosis of blood borne infections using African trypanosomes as a model system. Parasites and Vectors, 4, 68. https://doi.org/10.1186/1756-3305-4-68

Background: Diagnosis of blood borne infectious diseases relies primarily on the detection of the causative agent in the blood sample. Molecular techniques offer sensitive and specific tools for this although considerable difficulties exist when us... Read More about The best practice for preparation of samples from FTA®cards for diagnosis of blood borne infections using African trypanosomes as a model system.

Constraints to estimating the prevalence of trypanosome infections in East African zebu cattle (2010)
Journal Article
Cox, A., Tosas, O., Tilley, A., Picozzi, K., Coleman, P., Hide, G., & Welburn, S. (2010). Constraints to estimating the prevalence of trypanosome infections in East African zebu cattle. Parasites and Vectors, 3(1), 82

In East Africa, animal trypanosomiasis is caused by many tsetse transmitted protozoan parasites including Trypanosoma vivax, T. congolense and subspecies of T. brucei s.l. (T. b. brucei and zoonotic human infective T. b. rhodesiense) that may co-circ... Read More about Constraints to estimating the prevalence of trypanosome infections in East African zebu cattle.

Molecular epidemiology of African sleeping sickness (2009)
Journal Article
Hide, G., & Tait, A. (2009). Molecular epidemiology of African sleeping sickness. Parasitology, 136(12), 1491-500. https://doi.org/10.1017/S0031182009990333

Human sleeping sickness in Africa, caused by Trypanosoma brucei spp. raises a number of questions. Despite the widespread distribution of the tsetse vectors and animal trypanosomiasis, human disease is only found in discrete foci which periodically g... Read More about Molecular epidemiology of African sleeping sickness.

Investigations by PCR analysis of neospora caninum prevalence and co-infection with toxoplasma gondii in naturally infected populations (2009)
Thesis
Hughes, J. Investigations by PCR analysis of neospora caninum prevalence and co-infection with toxoplasma gondii in naturally infected populations. (Thesis). Salford : University of Salford

Neospora caninum and Toxoplasma gondii are closely related intracellular protozoan parasites associated with abortion in mammals. TV! caninum was identified in 1984, described as a new species in 1988 and often previously misidentified as T. gondii... Read More about Investigations by PCR analysis of neospora caninum prevalence and co-infection with toxoplasma gondii in naturally infected populations.