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The omega-3 fatty acid, eicosapentaenoic acid (EPA), prevents the damaging effects of tumour necrosis factor (TNF)-alpha during murine skeletal muscle cell differentiation (2008)
Journal Article
Magee, P., Pearson, S., & Allen, J. (2008). The omega-3 fatty acid, eicosapentaenoic acid (EPA), prevents the damaging effects of tumour necrosis factor (TNF)-alpha during murine skeletal muscle cell differentiation. Lipids in Health and Disease, 7(1), 24. https://doi.org/10.1186/1476-511X-7-24

Background: Eicosapentaenoic acid (EPA) is a -3 polyunsaturated fatty acid with antiinflammatory
and anti-cachetic properties that may have potential benefits with regards to skeletal muscle atrophy conditions where inflammation is present. It is al... Read More about The omega-3 fatty acid, eicosapentaenoic acid (EPA), prevents the damaging effects of tumour necrosis factor (TNF)-alpha during murine skeletal muscle cell differentiation.

Gender-specific in vivo measurement of the structural and mechanical properties of the human patellar tendon (2007)
Journal Article
Onambele, G., Burgess, K., & Pearson, S. (2007). Gender-specific in vivo measurement of the structural and mechanical properties of the human patellar tendon. Journal of Orthopaedic Research, 25(12), 1635-1642. https://doi.org/10.1002/jor.20404

Human patellar tendon stress (σ), strain (ε), stiffness (K), and tensile or Young's modulus (E), are determined in vivo through voluntary isometric contractions monitored with B-mode ultrasonography. The limitations in previous studies are: (1) they... Read More about Gender-specific in vivo measurement of the structural and mechanical properties of the human patellar tendon.

Plyometric vs. isometric training influences on tendon properties and muscle output (2007)
Journal Article
Burgess, K., Connick, M., Graham-Smith, P., & Pearson, S. (2007). Plyometric vs. isometric training influences on tendon properties and muscle output. Journal of Strength and Conditioning Research, 21(3), 986-989

The purpose of this study was to concurrently determine the effect that plyometric and isometric training has on tendon stiffness (K) and muscle output characteristics to compare any subsequent changes. Thirteen men trained the lower limbs either ply... Read More about Plyometric vs. isometric training influences on tendon properties and muscle output.

Creep and the in vivo assessment of human patellar tendon mechanical properties (2007)
Journal Article
Pearson, S., Burgess, K., & Onambele, G. (2007). Creep and the in vivo assessment of human patellar tendon mechanical properties. Clinical Biomechanics, 22(6), 712-717. https://doi.org/10.1016/j.clinbiomech.2007.02.006

Background: Owing to the viscoelastic nature of tendons it may be that the total excursion and hence strain experienced by the tendon under load may be affected by the duration of contraction. Here we examine the effect of contraction duration on the... Read More about Creep and the in vivo assessment of human patellar tendon mechanical properties.

Time-of-day effect on patella tendon stiffness alters vastus lateralis fascicle length but not the quadriceps force-angle relationship (2007)
Journal Article
Onambele-Pearson, G., & Pearson, S. (2007). Time-of-day effect on patella tendon stiffness alters vastus lateralis fascicle length but not the quadriceps force-angle relationship. Journal of Biomechanics, 40(5), 1031-1037. https://doi.org/10.1016/j.jbiomech.2006.04.001

Aim:
To examine the time-of-day (TOD) effect on torque–force/angle, fibre length (FL), tendon stiffness (K), stress, and strain using the quadriceps muscle–tendon complex as a model.

Methods:
Twelve healthy young men (aged 27±2.0 years) were stu... Read More about Time-of-day effect on patella tendon stiffness alters vastus lateralis fascicle length but not the quadriceps force-angle relationship.

Power output and muscle myosin heavy chain composition in young and elderly men (2006)
Journal Article
Pearson, S., Cobbold, M., Orrell, R., & Harridge, S. (2006). Power output and muscle myosin heavy chain composition in young and elderly men. Medicine and Science in Sports and Exercise, 38(9), 1601-1607. https://doi.org/10.1249/01.mss.0000227638.75983.9d

Purpose: Aging is associated with a decline in muscle volume, power output, and the velocity at which peak power (Vopt) occurs. The current study aimed to examine the relationship between lower-limb power output characteristics, muscle myosin heavy c... Read More about Power output and muscle myosin heavy chain composition in young and elderly men.

Influence of time of day on tendon compliance and estimations of voluntary activation levels (2006)
Journal Article
Pearson, S., & Onambele, G. (2006). Influence of time of day on tendon compliance and estimations of voluntary activation levels. Muscle and Nerve, 33(6), 792-800. https://doi.org/10.1002/mus.20529

We investigated the importance of tendon stiffness on estimations of central activation capacity (CAC). Patella tendon-force elongation relationship, quadriceps torque, and response to 50-micros, 100-HZ electrical twitch doublets were studied at appr... Read More about Influence of time of day on tendon compliance and estimations of voluntary activation levels.

Acute changes in knee-extensors torque, fiber pennation, and tendon characteristics. (2005)
Journal Article
Pearson, S., & Onambele, G. (2005). Acute changes in knee-extensors torque, fiber pennation, and tendon characteristics. Chronobiology International, 22(6), 1013-1027. https://doi.org/10.1080/07420520500397900

The aim of the current study was to examine the relationships between quadriceps torque, vastus lateralis pennation angle (theta), and patella tendon stiffness (K) at 07:45 and 17:45 h. Using short-duration static contractions, simultaneous recording... Read More about Acute changes in knee-extensors torque, fiber pennation, and tendon characteristics..

Power output of the lower limb during variable inertial loading : A comparison between methods using single and repeated contractions (2004)
Journal Article
Pearson, S., Cobbold, M., & Harridge, S. (2004). Power output of the lower limb during variable inertial loading : A comparison between methods using single and repeated contractions. European Journal of Applied Physiology, 92(1-2), 176-181. https://doi.org/10.1007/s00421-004-1046-0

The power-inertial load relationship of the lower limb muscles was studied during a single leg thrust using the Modified Nottingham Power Rig (mNPR) and during cycling exercise in nine young male subjects. The relationship between peak power and iner... Read More about Power output of the lower limb during variable inertial loading : A comparison between methods using single and repeated contractions.

Muscle function in elite master weightlifters (2002)
Journal Article
Pearson, S., Young, A., Macaluso, A., Devito, G., Nimmo, M., Cobbold, M., & Harridge, S. (2002). Muscle function in elite master weightlifters. Medicine and Science in Sports and Exercise, 34(7), 1199-1206. https://doi.org/10.1097/00005768-200207000-00023

Purpose: To determine whether explosive power and isometric strength of the lower-limb muscles in elite master Olympic weightlifters declines at a similar rate to nontrained healthy controls with increasing age. Methods: 54 elite level masters weight... Read More about Muscle function in elite master weightlifters.

A variable inertial system for measuring the contractile properties of human muscle (2001)
Journal Article
Pearson, S., Harridge, S., Grieve, D., Donald, W., Young, A., & Woledge, R. (2001). A variable inertial system for measuring the contractile properties of human muscle. Medicine and Science in Sports and Exercise, 33(12), 2072-2076. https://doi.org/10.1097/00005768-200112000-00015

Purpose: A flywheel system of variable inertia is described for inferring the mechanical properties of human muscle during a single explosive movement.

Methods: The system consists of a lightweight aluminum disk mounted on a shaft onto which a dri... Read More about A variable inertial system for measuring the contractile properties of human muscle.

Automated speckle tracking in ultrasound images of tendon movements
Thesis
Mohamed, A. (in press). Automated speckle tracking in ultrasound images of tendon movements. (Thesis). University of Salford

The central aim of this thesis was to develop new tracking software employing various image tracking algorithms for tracking the speckled movement of the tendon image captured using dynamic B-mode ultrasound imaging. The algorithms were selected base... Read More about Automated speckle tracking in ultrasound images of tendon movements.

Lower limb stiffness: Considerations for female athletes
Journal Article
McMahon, J., Comfort, P., & Pearson, S. Lower limb stiffness: Considerations for female athletes. Strength and Conditioning Journal, 34(5), 70-73. https://doi.org/10.1519/SSC.0b013e318268131f

Women demonstrate lower limb stiffness recruitment strategies, which may predispose them to greater sustainment of lower limb injuries, particularly to the anterior cruciate ligament. To positively alter such strategies in women, lower limb muscle st... Read More about Lower limb stiffness: Considerations for female athletes.