Outputs (46)

Triptolide induces pro-apoptotic effects against medulloblastoma subtypes (2025)
Presentation / Conference Contribution

Introduction
Medulloblastoma is a common cause of cancer in children, accounting for 20-25% of all paediatric brain tumours worldwide (de Medeiros et al., 2019). Whilst current treatments are effective, they are associated with substantial off-targe... Read More about Triptolide induces pro-apoptotic effects against medulloblastoma subtypes.

Celastrol induces pro-apoptotic and anti-migratory effects against medulloblastoma subtypes (2025)
Presentation / Conference Contribution

Introduction
Medulloblastoma accounts for 20-25% of all paediatric brain tumours diagnosed worldwide (de Medeiros et al., 2019). Current treatment regimens are effective. However, most options lead to long-term off-target effects. Therefore, the con... Read More about Celastrol induces pro-apoptotic and anti-migratory effects against medulloblastoma subtypes.

Triptonide induces pro-apoptotic effectsagainst medulloblastoma subtypes (2025)
Presentation / Conference Contribution

Introduction
Medulloblastoma is a major cause of paediatric braintumours worldwide. Whilst effective, current treatmentsare often associated with lifelong off-target effectsresulting in lower quality of life and early mortality inpaediatric patients... Read More about Triptonide induces pro-apoptotic effectsagainst medulloblastoma subtypes.

Trogocytosis: revealing new insights into parasite–host interactions (2025)
Journal Article

Trogocytosis – a process whereby cells physically nibble and ingest membrane fragments and other components from neighboring cells – plays a critical role in host–parasite interactions by modulating parasite survival and host immune responses. This r... Read More about Trogocytosis: revealing new insights into parasite–host interactions.

Characterization of a trypanosome from large yellow croaker (Larimichthys crocea), cage-cultured in seawater, in China (2025)
Journal Article

A significant outbreak of trypanosomosis occurred in farmed large yellow croaker (Larimichthys crocea) in Southeast China resulting in daily mortality rates, over 70 days, of up to 1 % with cumulative losses nearing 60 %. Despite the severity of the... Read More about Characterization of a trypanosome from large yellow croaker (Larimichthys crocea), cage-cultured in seawater, in China.

COVID-19’s impact on physical activity and metabolic syndrome in firefighters: A randomized trial of pre- and post-recovery analysis (2025)
Journal Article

Objective: Despite the physical demands of their job, firefighters often experience declining health, a trend that has worsened with coronavirus infection. We investigated the correlation between physical activity (PA) and metabolic syndrome (MS) ris... Read More about COVID-19’s impact on physical activity and metabolic syndrome in firefighters: A randomized trial of pre- and post-recovery analysis.

Thirteen leading public health organisations call on Government to outlaw physical punishment (2025)
Newspaper / Magazine

Leading health organisations have joined together in calling for the removal of the "reasonable punishment" defence in England as part of the Children's Wellbeing and Schools Bill.

Chronotype Predicts Body Mass Index via Emotion Regulation Strategy Use and Emotional Eating (2025)
Journal Article

Introduction: Rates of obesity are increasing across all regions representing a critical public health concern. An evening chronotype has been associated with elevated body mass index and a less nutritious diet. However, the mechanisms underpinning t... Read More about Chronotype Predicts Body Mass Index via Emotion Regulation Strategy Use and Emotional Eating.

Body-weight functional exercise promotes greater and safer blood glucose reduction compared to aerobic and strength exercises in type 1 diabetics: a randomised crossover study. (2025)
Journal Article

Aerobic and strength exercises are commonly recommended for patients with type-1 diabetes (T1DM) but may not suit everyone. Body-weight functional exercise (BWFE) could offer an alternative for diabetes management. We aimed to compare blood glucose (... Read More about Body-weight functional exercise promotes greater and safer blood glucose reduction compared to aerobic and strength exercises in type 1 diabetics: a randomised crossover study..

KidsCan Connect – Creating a social platform for children undergoing cancer treatment (2025)
Presentation / Conference Contribution

Exploring domestic garden identities: personal histories from older people in the Netherlands (2024)
Journal Article

Domestic gardens are spaces imbued with meaning, expression, and identity. This paper seeks to explore garden identities across their lifespan in the Netherlands by investigating older people’s personal histories through thematic analysis. Oral histo... Read More about Exploring domestic garden identities: personal histories from older people in the Netherlands.

Revealing the progression and pathologic features of intraperitoneal infection of Trichomonas vaginalis in mice via parasite α-actinin-based immunological detection (2024)
Journal Article

Background: Trichomoniasis caused by Trichomonas vaginalis is the most prevalent nonviral sexually transmitted disease in women and has frequently damaged public health. To better use the animal model and take a step forward fully elucidating this pa... Read More about Revealing the progression and pathologic features of intraperitoneal infection of Trichomonas vaginalis in mice via parasite α-actinin-based immunological detection.

Toxoplasma gondii (2024)
Other

Multiomics of parkinsonism cynomolgus monkeys highlights significance of metabolites in interaction between host and microbiota (2024)
Journal Article

The gut microbiota has been demonstrated to play a significant role in the pathogenesis of Parkinson’s disease (PD). However, conflicting findings regarding specific microbial species have been reported, possibly due to confounding factors within hum... Read More about Multiomics of parkinsonism cynomolgus monkeys highlights significance of metabolites in interaction between host and microbiota.

First outbreak of trypanosomiasis in farmed blood parrot cichlids (Vieja melanura♀ × Amphilophus citrinellus♂) from southern China (2024)
Journal Article

Outbreaks of fish trypanosomiasis are regularly reported in cultured groupers (Epinephelus spp.), largemouth bass (Micropterus salmoides), and many other species of Cyprinidae, but only rarely reported in ornamental fish. This study reports a trypano... Read More about First outbreak of trypanosomiasis in farmed blood parrot cichlids (Vieja melanura♀ × Amphilophus citrinellus♂) from southern China.

Apicomplexa micropore: history, function, and formation (2024)
Journal Article

The micropore, a mysterious structure found in apicomplexan species, was recently shown to be essential for nutrient acquisition in Plasmodium falciparum and Toxoplasma gondii. However, the differences between the micropores of these two parasites qu... Read More about Apicomplexa micropore: history, function, and formation.

The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival (2024)
Journal Article

The apicoplast is a four-membrane plastid found in the apicomplexans, which harbors biosynthesis and organelle housekeeping activities in the matrix. However, the mechanism driving the flux of metabolites, in and out, remains unknown. Here, we used T... Read More about The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival.

Prevalence of Eimeria Species, Detected by ITS1-PCR Immobilized on FTA Cards, in Future Laying Hens and Breeding Hens in Six Provinces in Northeastern Algeria (2024)
Journal Article

Purpose
Avian coccidiosis is an important and widely distributed disease that affects global agricultural economies through losses. In Algeria, there is limited epidemiological and ecological knowledge about this disease and this hinders implementat... Read More about Prevalence of Eimeria Species, Detected by ITS1-PCR Immobilized on FTA Cards, in Future Laying Hens and Breeding Hens in Six Provinces in Northeastern Algeria.

Functional screening reveals Toxoplasma prenylated proteins required for endocytic trafficking and rhoptry protein sorting (2023)
Journal Article

In the apicomplexans, endocytosed cargos (e.g., hemoglobin) are trafficked to a specialized organelle for digestion. This follows a unique endocytotic process at the micropore/cytostome in these parasites. However, the mechanism underlying endocytic... Read More about Functional screening reveals Toxoplasma prenylated proteins required for endocytic trafficking and rhoptry protein sorting.

Improving outcomes for children and young people with special educational needs (2023)
Book Chapter

An overview of a project aimed at improving outcomes for children with SEND needs and underpinning principles