Outputs (38)

Towards a classification strategy for complex nanostructures (2017)
Journal Article

The range of possible nanostructures is so large and continuously growing, that collating and unifying the knowledge connected to them, including their biological activity, is a major challenge. Here we discuss a conception that is based on connectio... Read More about Towards a classification strategy for complex nanostructures.

Detecting the shape of anisotropic gold nanoparticles in dispersion with single particle extinction and scattering (2017)
Journal Article

The shape and size of nanoparticles are important parameters affecting the biodistribution, bioactivity, and toxicity. The
high-throughput characterisation of nanoparticle shape in the dispersion is a fundamental prerequisite for realistic in vitro... Read More about Detecting the shape of anisotropic gold nanoparticles in dispersion with single particle extinction and scattering.

Detecting the shape of anisotropic gold nanoparticles in dispersion with single particle extinction and scattering (2017)
Journal Article

The shape and size of nanoparticles are important parameters affecting the biodistribution, bioactivity, and toxicity. The
high-throughput characterisation of nanoparticle shape in the dispersion is a fundamental prerequisite for realistic in vitro... Read More about Detecting the shape of anisotropic gold nanoparticles in dispersion with single particle extinction and scattering.

Mapping protein binding sites on the biomolecular corona of nanoparticles (2015)
Journal Article

Nanoparticles in a biological milieu are known to form a sufficiently long-lived and well-organized ‘corona’ of biomolecules to confer a biological identity to the particle. Because this nanoparticle–biomolecule complex interacts with cells and biolo... Read More about Mapping protein binding sites on the biomolecular corona of nanoparticles.

Revealing DNA interactions with exogenous agents by surface-enhanced raman scattering (2014)
Journal Article
Masetti, M., Xie, H., Krpetic, Z., Recanatini, M., Alvarez-Puebla, R., & Guerrini, L. (2015). Revealing DNA interactions with exogenous agents by surface-enhanced raman scattering. Abstracts of papers / American Chemical Society, 137(1), 469-476. https://doi.org/10.1021/ja511398w

The standard protocols for DNA analysis largely involve polymerase chain reaction (PCR). However, DNA structures bound to chemical agents cannot be PCR-amplified, and therefore any sequence changes induced by external agents may be neglected. Thus, t... Read More about Revealing DNA interactions with exogenous agents by surface-enhanced raman scattering.

Direct surface-enhanced raman scattering analysis of DNA duplexes (2014)
Journal Article
Guerrini, L., Krpetic, Z., Van Lierop, D., Alvarez-Puebla, R., & Graham, D. (2014). Direct surface-enhanced raman scattering analysis of DNA duplexes. Angewandte Chemie International Edition, 54(4), 1144-1148. https://doi.org/10.1002/anie.201408558

The exploration of the genetic information carried by DNA has become a major scientific challenge. Routine DNA analysis, such as PCR, still suffers from important intrinsic limitations. Surface-enhanced Raman spectroscopy (SERS) has emerged as an out... Read More about Direct surface-enhanced raman scattering analysis of DNA duplexes.

Interactions of gold nanoparticles with a phospholipid monolayer membrane on mercury (2014)
Journal Article
Gordillo, G., Krpetic, Z., & Brust, M. (2014). Interactions of gold nanoparticles with a phospholipid monolayer membrane on mercury. ACS nano, 8(6), 6074-6080. https://doi.org/10.1021/nn501395e

It is demonstrated that a compact monolayer of 1,2-dioleoyl-sn-glycero-3-phosphocholine adsorbed to a hanging mercury drop electrode can serve as a simple electrochemical model system to study biomembrane penetration by gold nanoparticles. The hydrog... Read More about Interactions of gold nanoparticles with a phospholipid monolayer membrane on mercury.

Nanomaterials : impact on cells and cell organelles (2014)
Book Chapter
Krpetic, Z., Anguissola, S., Garry, D., Kelly, P., & Dawson, K. (2014). Nanomaterials : impact on cells and cell organelles. In Nanomaterial : impacts on cell biology and medicine (135-156). Springer Netherlands. https://doi.org/10.1007/978-94-017-8739-0_8

Colloidal nanoparticles designed for the interactions with cells are very small, nanoscale objects usually consisting of inorganic cores and organic shells that are dispersed in a buffer or biological medium. By tuning the material properties of the... Read More about Nanomaterials : impact on cells and cell organelles.

Preparation and characterization of au nanoparticles capped with mercaptocarboranyl clusters (2013)
Journal Article
M. Cioran, A., Teixidor, F., Krpetic, Ž., Brust, M., & Viñas, C. (2014). Preparation and characterization of au nanoparticles capped with mercaptocarboranyl clusters. Dalton Transactions, 43(13), 5054-5061. https://doi.org/10.1039/C3DT52872C

The preparation of 3–4 nm and 10 nm gold nanoparticles capped with neutral carborane-based mercaptocarboranes, via two different preparative routes, is reported. The resulting boron-enriched nanomaterials exhibit complete dispersibility in water, ope... Read More about Preparation and characterization of au nanoparticles capped with mercaptocarboranyl clusters.

Conjugation of PEG and gold nanoparticles to increase the accessibility and valency of tethered RNA splicing enhancers (2013)
Journal Article
Perrett, A., Dickinson, R., Krpetic, Z., Brust, M., Lewis, H., Eperon, I., & Burley, G. (2013). Conjugation of PEG and gold nanoparticles to increase the accessibility and valency of tethered RNA splicing enhancers. Chemical Science, 4(1), 257-265. https://doi.org/10.1039/C2SC20937C

Since alternative splicing patterns are exhibited by most mammalian genes, the functional properties of a gene may be changed for therapeutic purposes by nudging splicing from one pattern to another. Splicing to a refractory exon can be enhanced usin... Read More about Conjugation of PEG and gold nanoparticles to increase the accessibility and valency of tethered RNA splicing enhancers.