All Outputs (47)

Pulmonary elimination rate of inhaled 99m Tc-sestamibi radioaerosol is delayed in healthy cigarette smokers (2008)
Journal Article
Ruparelia, P., Cheow, H., Evans, J., Banney, L., Shankar, S., Szczepura, K., …Peters, A. (2008). Pulmonary elimination rate of inhaled 99m Tc-sestamibi radioaerosol is delayed in healthy cigarette smokers. British Journal of Clinical Pharmacology, 65(4), 611-614. https://doi.org/10.1111/j.1365-2125.2008.03099.x

Aim - To explore inhaled technetium-99m-labelled hexakis-methoxy-isobutyl isonitrile (99mTc-sestamibi) for quantifying pulmonary P-glycoprotein(P-gp) expression. Methods - The elimination rate from the lungs of 99mTc-sestamibi was recorded scintigra... Read More about Pulmonary elimination rate of inhaled 99m Tc-sestamibi radioaerosol is delayed in healthy cigarette smokers.

Healthy passive cigarette smokers have increased pulmonary alveolar permeability (2007)
Journal Article
Beadsmoore, C., Cheow, H., Szczepura, K., Ruparelia, P., & Michael Peters, A. (2007). Healthy passive cigarette smokers have increased pulmonary alveolar permeability. Nuclear Medicine Communications, 28(2), 75-77. https://doi.org/10.1097/MNM.0b013e328013eb1e

Question Does passive smoking have a measurable effect on lung function in otherwise healthy subjects? There is current interest concerning passive smoking but no objective evidence showing that it has any impact on lung function. Methods The... Read More about Healthy passive cigarette smokers have increased pulmonary alveolar permeability.

P16 Healthy passive cigarette smokers have increased pulmonary alveolar permeability (2006)
Journal Article
Beadsmoore, C., Cheow, H., Szczepura, K., Ruparelia, P., & Peters, A. (2006). P16 Healthy passive cigarette smokers have increased pulmonary alveolar permeability. Nuclear Medicine Communications, 27(12), 1027-1028. https://doi.org/10.1097/00006231-200612000-00067

Background and aim To determine whether passive smoking has a measurable effect on lung function in otherwise healthy subjects? There is current interest concerning passive smoking but no objective evidence showing that it has any impact on lung func... Read More about P16 Healthy passive cigarette smokers have increased pulmonary alveolar permeability.

Granulocyte trafficking in chronic obstructive pulmonary disease (2006)
Journal Article
Ruparelia, P., Szczepura, K., Bilton, D., Peters, A., & Chilvers, E. (2006). Granulocyte trafficking in chronic obstructive pulmonary disease. Thorax, 61(Sup. 2), ii108-ii109

Introduction: Chronic obstructive pulmonary disease (COPD) is an inflammatory condition of the airways characterised by intense neutrophilia. We have used sub-imaging doses of 111 indium (111In) labelled granulocytes and high sensitivity whole body c... Read More about Granulocyte trafficking in chronic obstructive pulmonary disease.

A16 Using whole-body counting to determine neutrophil trafficking and loss in COPD (2006)
Journal Article
Szczepura, K., Ruparelia, P., Bilton, D., Chilvers, E., & Peters, A. (2006). A16 Using whole-body counting to determine neutrophil trafficking and loss in COPD. Nuclear Medicine Communications, 27(3), 285. https://doi.org/10.1097/00006231-200603000-00027

COPD is an inflammatory condition of the airways characterized by airway neutrophilia. Using a whole-body-counter (WBC) we have assessed neutrophil trafficking and loss in COPD using small activities of 111In-labelled neutrophils. Patients were scann... Read More about A16 Using whole-body counting to determine neutrophil trafficking and loss in COPD.

Quantification of disease activity in patients undergoing leucocyte scintigraphy for suspected inflammatory bowel disease (2004)
Journal Article
Cheow, H., Voutnis, D., Evans, J., Szczepura, K., Swift, E., Bird, N., …Peters, A. (2005). Quantification of disease activity in patients undergoing leucocyte scintigraphy for suspected inflammatory bowel disease. European Journal of Nuclear Medicine and Molecular Imaging, 32(3), 329-337. https://doi.org/10.1007/s00259-004-1617-7

Purpose Whole-body gamma camera counting is an alternative to faecal 111In collection for quantifying disease activity in inflammatory bowel disease (IBD) but requires administration of imaging activities of 111In. The aim of this study was to explo... Read More about Quantification of disease activity in patients undergoing leucocyte scintigraphy for suspected inflammatory bowel disease.

P25. Tolerance and diagnostic accuracy of myocardial scintigraphy with adenosine infusion, 6 min (standard) versus 3 min (abbreviated) protocol (2003)
Journal Article
Gopinath, G., Buscombe, J., Naojee, S., Szczepura, K., & Hilson, A. (2003). P25. Tolerance and diagnostic accuracy of myocardial scintigraphy with adenosine infusion, 6 min (standard) versus 3 min (abbreviated) protocol. Nuclear Medicine Communications, 24(4), 476. https://doi.org/10.1097/00006231-200304000-00114

Myocardial perfusion scintigraphy with adenosine is an effective and safe method for diagnosing coronary artery disease (CAD). Various reports suggest that a 3 min stress regime is as efficacious as a 6 min regime. The aim of the study was to study t... Read More about P25. Tolerance and diagnostic accuracy of myocardial scintigraphy with adenosine infusion, 6 min (standard) versus 3 min (abbreviated) protocol.